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Post by prosper on Feb 16, 2019 8:59:38 GMT -5
VDEX is one avenue, but I have had a thought for a while. There are thousands of Urgent Care type locations in the US. They all have doctors. Why could we not target them. An already diagnosed diabetic would have statistics and records of their current diagnosis and treatments. All the Urgent Care type locations would need is an inexpensive Spirometer that I believe Mannkind has made available at very reasonable prices.
Comments appreciated.
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Post by markado on Feb 16, 2019 8:59:47 GMT -5
There's a pay to play element to just about every business. Seems like it might be worth $500k to be listed as a partner, in the company if multi billion dollar inulin companies.
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Post by MnkdWASmyRtrmntPlan on Feb 16, 2019 11:44:44 GMT -5
Is that what you’re expecting Kendall is working on when you say “he is working on SOC?....is it just to get the trials going? I thought he would be able to get changes sooner. Before Dr. Kendall came to MNKD he reviewed 60+ studies which had already been done but mostly not published. Al Mann wanted answers to every question but never saw MNKD as a sales and marketing company and always expected to have every BP wanting to partner when they saw his studies.
Al was wrong. BP saw afrezza as an industry killer. If you start treating the early T2s with afrezza they don't progress and some in three to six months might see enough beta cell regeneration they don't even need to be on meds.
For the T1s all that is left is the basal market but not much need for the complicated pumps and AP devices. A simple patch pump will do. The basal market without the progressing T2s is not a very large market. Step 4 of the SOC is never reached nor Steps 1 through 3, just give them the afrezza from day one, including the prediabetics.
With out peer reviewed official studies which are presented on the big stage at ADA2019 the community is not going to listen. In addition you have all the politicing behind the scenes before and after the big show. That is what Dr. Kendall is working on. Its a terrible, political process not driven by fact but rather opinionated manipulated studies. Just take the SGLT2 study which was put together to say they have no impact on amputations. Two months later we have another study presented in the EU saying there is no doubt guys are loosing their balls thanks to SGLT2 in addition to toes and feet.
When Dr. Kendall joined he said this was the easiest job he has ever had. Some of us smiled knowing this was going to be a long slog and he will get there but it just is not going to be easy. The ADA and the Endos are mostly about the money not the PWDs, sad but true.
I loved your post, Sayhey. Such wise and interesting perspective; so insightful; even poetic. It's kinda like what we all have known all along, but were unable to articulate, along with important stuff that we didn't know, but do now. Additional parts of the Mannkind story. And, why we are all so committed to hold. We all know ... Mannkind's day will come; diabetics day will come; our day will come. When you think about it, you have to believe it is true that Al expected all the other BPs to come knocking at his door. That would only be expected. It is bold to call Al wrong, but there are so many perspectives and forces in that huge arena that he operated in. It's impossible to predict the future with all those unknowns. The capitalistic forces are so powerful ... industry killer? Squash it! I'm very interested in your comment about T2's beta cell regeneration with Afrezza. I believe that is true, but conceptually, I need some help. I am thinking that the edges are blurred between Types 1, 2 and 3 (auto-immune, insulin resistant and alzheimer's). It's not black and white categories like most talk about it. It seems that for a Type 2 to regenerate beta cells is referring to type 1-1/2 (type one and a half). That is, insulin-resistance with an auto-immune component. I have been thinking that all three types are intertwined to various degrees in people, and that the distinctions between the 3 types are blurred. Not black and white at all, but just different perspectives or manifestations of an endocrine system gone astray. I know, this all sounds like a bunch of sh!t, and I really don't know what I am talking about, and I admit that I certainly don't, but I am just throwing my thoughts and questions out there. So, I am wondering if there is not really a distinction between types 1 and 2, like the type 1-1/2 that seems to be gaining acceptance, or do the different types just sometimes exist in some people simultaneously? IOW, when people are both Type 1 and Type 2 simultaneously. Or, perhaps, when people get insulin resistant, it just helps them to have more insulin to be able to perform the glucose delivery task because of all their defective insulin receptors. And, then that has the additional benefit of allowing the pancreas to rest and maybe even build new beta cells. Which gets to another thought. Does Afrezza allow the pancreas to "build" new beta cells for type 2, and "regenerate" beta cells for type 1? Or, are the terms building new and regenerating old not really distinct or important? Ah, to me, the endocrine system is just such a marvel. So complex. So beautiful. God-like. But, still, fallible. Which is understandable considering all the crap we subject it to ... crappy, processed, synthetic, plastic, so-called food and all the toxins. Ok, my questions and thoughts have meandered off an exit ramp and into a rant, so I will stop. But, I hope this generates some discussion. Maybe this is off the discussion of Banting, but then, maybe not. Really interesting about the SGLT2 studies. I am not familiar with that, but I totally believe it. Wow. Deception is such a big part of MNKD's battle. Like the fake-news in our current politics. Perhaps the word Dr. Kendall meant to say instead of "easy" is "fun". Or, maybe "rewarding". |
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Post by MnkdWASmyRtrmntPlan on Feb 16, 2019 11:49:07 GMT -5
VDEX is one avenue, but I have had a thought for a while. There are thousands of Urgent Care type locations in the US. They all have doctors. Why could we not target them. An already diagnosed diabetic would have statistics and records of their current diagnosis and treatments. All the Urgent Care type locations would need is an inexpensive Spirometer that I believe Mannkind has made available at very reasonable prices. Comments appreciated. OK, I'll bite. Who would be targeted? The urgent care facility? It is the doctors that prescribe. Besides, with Afrezza, patients need patience.  They need to be assisted with using Afrezza. They need help over time while they are learning to use it. They need compassion and caring. They need Vdex. Urgent cares are not really the place for that. Is there an angle/perspective I am not thinking of? |
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Post by mytakeonit on Feb 16, 2019 13:16:37 GMT -5
Maybe we can hawk it on a busy NYC street outside of a fancy restaurant. When the rich people with CGM's come out ... Aloha! Try this 4 unit inhaler and watch your CGM for the next hour and a half. I promise you that you'll be back soon! $2 please . (That Aloha will always get their attention)
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Post by boca1girl on Feb 16, 2019 15:27:11 GMT -5
Maybe we can hawk it on a busy NYC street outside of a fancy restaurant. When the rich people with CGM's come out ... Aloha! Try this 4 unit inhaler and watch your CGM for the next hour and a half. I promise you that you'll be back soon! $2 please . (That Aloha will always get their attention) Would be a good idea if it were OTC vs prescription. |
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Dartman
Newbie
Posts: 21 
Sentiment: Way Too Long
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Post by Dartman on Feb 19, 2019 14:14:21 GMT -5
A slush fund is normally ... only enough to buy slush. I thought it was called a shave ice fund in the islands... |
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Post by mytakeonit on Feb 19, 2019 15:32:16 GMT -5
We changed it to snow cone ... because the tourist insisted on calling it that. So, change the name and charge them $1 extra. I still think they should have stayed with shave ice.
Oh I forgot, some tourist also tried to correct us and said ... "It's shaved ice ... shaved" Okay fine ... charge them another $1 ... I mean, it is our product after all.
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Post by peppy on Mar 10, 2019 14:57:18 GMT -5
This is distressing. the inmates are running the asylum.  |
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Post by barnstormer on Mar 10, 2019 15:21:15 GMT -5
This is distressing. the inmates are running the asylum. Well MNKD isn't a sponsor or strategic partner because Mike says the attendees aren't MNKDs target market. So why did hire and tout Kendall, former Cheif Med Officer for ADA? Mike doesn't even think attending is worth the price of admission. Apparently the companies on this list think ADA is worth attending. So yes they are mostly global companies and will be able to shake hands with those foreign prescribers. Begs the question, how did they become global insulin suppliers? What about the BIOMM and Cipla region attendees? Does anyone at ADA still remember Kendall? We aren't at AMGEN anymore. |
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Post by mango on Mar 11, 2019 22:34:07 GMT -5
This is distressing. the inmates are running the asylum. Well MNKD isn't a sponsor or strategic partner because Mike says the attendees aren't MNKDs target market. So why did hire and tout Kendall, former Cheif Med Officer for ADA? Mike doesn't even think attending is worth the price of admission. Apparently the companies on this list think ADA is worth attending. So yes they are mostly global companies and will be able to shake hands with those foreign prescribers. Begs the question, how did they become global insulin suppliers? What about the BIOMM and Cipla region attendees? Does anyone at ADA still remember Kendall? We aren't at AMGEN anymore. It appears that Mike wants nothing to do with this criminal organization. MannKind is the epitome of a Good Pharmaceutical Company. But, the day MannKind joins the circle of Bantiing Elites with this corrupt organization is the day I sell all my shares and put MannKind on my radar. I want nothing to do with Evil, and currently, ADA is Evil (...along with most, (maybe all), of its supporters...). I believe the ethical foundation laid by Al Mann will help the World. Saving the world requires Three P's: Passion, Patience, and Persistence. Not Two: Pay to Play. (no disrespect, jus my thoughts) |
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Post by boca1girl on Mar 12, 2019 7:17:38 GMT -5
Maybe it’s a new twist on “if you can’t beat um, join um”.
If we don’t want to join them, then we will need to beat them at their own game.
Dr. K, Beijing a former insider, could be the ADA’s worst enemy.
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They need to be assisted with using Afrezza. They need help over time while they are learning to use it. They need compassion and caring. They need Vdex. Urgent cares are not really the place for that. Is there an angle/perspective I am not thinking of?
