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Post by mnholdem on Oct 23, 2014 12:00:02 GMT -5
Did you know that MannKind's Technosphere-Inhaled GLP-1 has completed Phase I testing in Europe? Find this and other trial results at the following link to the EMA site. I haven't had time to read through them all, but perhaps there are some nuggets to be found?
www.clinicaltrialsregister.eu/ctr-search/search?query=insulin+AND+Mannkind
P.S. Apologies if this has already been posted.
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Post by jpg on Oct 23, 2014 13:13:33 GMT -5
If it has been posted I certainly wasn't aware. Nice find. Thank you. The study was started in 2008 so probably finished in late 2009 and put on the back burner once the 2nd CRL came in. I wouldn't be surprised if we hear something about sooner then later...
JPG
EudraCT Number: 2007-003430-42 Sponsor Protocol Number: MKC-253-002 Start Date*: 2008-01-15
Sponsor Name:MannKind Corporation
Full Title: A Phase 1, Repeated Single-Dose, Double Blind, Randomized Five Treatment Controlled Safety and Pharmacological Response Evaluation Trial of MKC253 Inhalation Powder in Adult Male and Postmenopausal...
Medical condition: Type 2 Diabetes Mellitus
Disease: Version SOC Term Classification Code Term Level
9.1 10045242 Type II diabetes mellitus LLT
Population Age: Adults, Elderly Gender: Male, Female
Trial protocol: NL (Completed)
Trial results: (No results available)
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Post by mrmookie123 on Oct 25, 2014 16:28:30 GMT -5
And you guys do realize this was 6 years ago ??
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Post by jpg on Oct 25, 2014 19:22:04 GMT -5
Yes it was a few years ago. Human biology hasn't changed that much since then. The drug would still work... And now Mannkimd has more money to move these types of initiatives forward if they so choose to.
JPG
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Post by mnholdem on Oct 25, 2014 20:01:59 GMT -5
Like I said, a haven't time to go through them all, but one of the Afrezza trials, MKC-TI-134, started Aug 14, 2013 and is ongoing...testing results with patients who have asthma or COPD. MannKind suspended development of pipeline a few years ago to devote financials resources to Afrezza. I also posted this link because if any new EU trials are started, we'd know. I'm planning on keeping an eye on Sanofi in case they are the sponsor.
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