Post by peppy on Nov 26, 2015 18:14:13 GMT -5
This train
Carries saints and sinners
This train
Carries losers and winners
This Train
Carries whores and gamblers
This Train
Carries lost souls
This Train
Dreams will not be thwarted
This Train
Faith will be rewarded
This Train
Hear the steel wheels singin'
This Train
Bells of freedom ringin'
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Matt;
When using injected insulin, the technique requires “pre-empting” dosing as long as 45 minutes before every meal, then waiting to start eating at the optimal time for each meal – once a curved pattern appears on the glucose meter display. With Afrezza, pre-dosing isn’t required with any meal, which greatly reduces the scope for timing errors.
The frequent dosing of injected insulin brings the challenges of stacking doses, that increase the likelihood of hypos. Sugar Surfing introduces the “i-chain” concept to deal with this problem, but the lack of a long tail of action makes Afrezza so much easier. screencast.com/t/1lw4RXiEpU
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Afrezza not covered health insurance quote:
POW 4 (30) & 8 (60) Unit
30 day supply is $292.13
90 day supply is $796.33
Is $3,505 a year if bought 30 day supply. = 11/day
$3,200 a 90 day supply = 10/day
I am going with these numbers now, as I had monthly cost as high as $4,374 a month. $1,114 dollar miss which would have been $12.15 a day.
If, Apidra $1,406.28 annually apidra
$3.90 day.
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lakers said:
At this juncture, Mnkd needs a CEO with different skill sets, especially negotiation skill, and authority.
deal making expertise.
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Al Mann holds 38%-40%? stake in Mannkind?
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The patents:
patentscope.wipo.int/search/en/result.jsf?currentNavigationRow=prev&prevCurrentNavigationRow=2&query=FP:(Mannkind)&office=&sortOption=Pub%20Date%20Desc&prevFilter=&maxRec=708&viewOption=All
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Land of hope and dreams:
Patents the negotiating power.
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Some people wonder why Hakan Edstrom is staying on.
Some one posted he is an excellent technician. He knows technosphere.
?
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sanofi/ regeneron
en.sanofi.com/investors/investors.aspx
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Sanofi
Sarilumab - Rheumatoid Arthritis
Dupilumab - asthma and atopic dermatitis
Praluent - alirocumab - cholesterol
(mab) [Abbr. of m(onoclonal) a(nti)b(ody)]
A suffix for monoclonal antibody.
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Afrezza included in Praluent trial.
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Mannkind patents:
- screencast.com/t/Gxfbnv02p71
- 38. 20030046714 Anti-neovasculature preparations for cancer
immunogenic compositions, methods of designing immunogenic compositions, methods of treatment using immunogenic compositions, methods of evaluating cell-mediated immunity resulting from immunogenic compositions, research models, and methods of making research models, all of which relate to targeting tumor vasculature.
- 45. 20040203051 Expression vectors encoding epitopes of target-associated antigens and methods for their design
The invention relates to epitope cluster regions and to vectors including epitope cluster regions. The invention also relates to a method of activating a T cell comprising contacting a substrate polypeptide with an APC and contacting the APC with a T cell.
- 51. 20060205032 hSLIM modulates immune responses
- 52. 6994851 Method of inducing a CTL response US 07.02.2006
A61K 39/00 09380534 MannKind Corporation Kundig Thomas M.
A method of inducing a cytotoxic T-lymphocyte (CTL) response to an antigen is disclosed. The method involves delivering the antigen to the lymphatic system of an animal regularly over a sustained period of time using, e.g., an osmotic pump. The method is advantageous over prior art methods for inducing a CTL response in that it does not require repetitive immunizations or the use of adjuvants. The method of the present invention can be used for the induction of CTLs in tumor or infectious disease immunotherapy.
61. 20070003563 Multivalent entrain-and-amplify immunotherapeutics for carcinoma US 04.01.2007
C07H 21/02 11455279 MannKind Corporation Bot Adrian Ion
The present invention provides a method of treating a cell proliferative disease such as cancer by providing to a subject in need thereof an immunogenic composition comprising plasmid and peptide(s) or analogues thereof. In embodiments of the present invention there is provided methods and compositions for inducing, entraining, and/or amplifying the immune response to MHC class-I restricted epitopes of carcinoma antigens to generate an effective anti-cancer immune response.
62. 20070003579 Allergen-specific immunotherapy
-63. 20060099269 Pulmonary delivery of inhibitors of phosphodiesterase type 5 US 11.05.2006
A61K 31/519 11210709 MannKind Corporation Cheatham Wayman Wendell
Provided herein are compositions of 1) diketopiperazine salts of PDE5 inhibitors, and 2) DKP microparticles having a PDE5 inhibitors thereon, as well as methods for the pulmonary delivery of these compositions for the treatment of pulmonary hypertension and sexual dysfunction(s).
- 65. 20070004662 Methods and compositions to elicit multivalent immune responses against dominant and subdominant epitopes, expressed on cancer cells and tumor stroma
- 66. 20070027063 METHOD OF PRESERVING THE FUNCTION OF INSULIN-PRODUCING CELLS
- 67. 20080199485 Method for enhancing T cell response
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This is result 70 out of 706.
* You guys are getting the idea, page after page, immunogenic
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Just throwing it out there into the atomosphere.
In the land of hopes and dreams.
