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Post by uvula on May 17, 2018 21:38:04 GMT -5
Sayhey, excellent answer to my uninformed question. Thank you.
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Post by sportsrancho on May 17, 2018 21:46:24 GMT -5
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Post by dreamboatcruise on May 18, 2018 0:19:14 GMT -5
If Dr. Kendall actually gets afrezza as the standard of care for both T1s and T2s does it matter if it is ultra, near-natural or just old-school rapid? Afrezza will be the only thing which will be used when it comes to the T2s and if cheap enough the only thing taken at meal time for the T1s. Didn't he just say something about the greatest advance in insulin in 93 years? Since Banting and Best? Maybe the label should just say "Stop the Banting, its the Best". I think getting it recognized for unique properties such as pk/pd is a small step towards getting it to be the "standard of care"... but if you think all doctors are going to start prescribing it tomorrow in preference to RAAs before a chance of a label change, then yes, the label change would be unexciting. You might be putting the cart way out in front of the horse, however. It's a long journey from management saying they have a great product to having it actually be one. I believe in the Intel approach, which was to always be a bit paranoid about your lead over competitors... build something great, but never assume it was that great. I hope Kendall isn't too much into hyping how great things already are... I'd hate for him to be embarrassed by the riches before he's actually done the hard work of making Afrezza not only a monetary success but a meaningful clinical advance for significant numbers of patients with diabetes.
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Post by ilovekauai on May 18, 2018 0:40:41 GMT -5
I just tried Afrezza again tonight with supper. My pre-supper BG was 138. I pan fried a 6 oz cut of steak, steamed one artichoke w/olive oil to dip in, one fresh small salad, and some bread, 1/2 orange, and one apricot for dessert.
I just did three post-meal testing and sitting at a rock solid BG of 82 right now with no low encountered whatsoever.
I did just one 8 unit cartridge for these results. This stuff is wonderful.
I only have two 8 unit cartridges left to experiment around with, but think I already got my dose figured out. I really don't need Afrezza during the day. Daily exercise works too and keeps my BG within a normal range, almost. It's the evening hours that I need Afrezza.
Anyone out there wanna help me get more Afrezza somehow? Can't believe its come to this. I'm just trying to get my hands on something that really works for my diabetes, like nothing else out there.
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Post by dreamboatcruise on May 18, 2018 0:42:07 GMT -5
Money talks and metfornin costs pennies per day. Insurances companies care more about cost than health. Will reduced complications offset the cost of afrezza? I don't know the answer. Well, there are two routes to get payers to cover. Prove that there is a cost savings over the relatively short time frame they use in their analysis... 3-5 years at best based on what I've gleaned from talking to execs in that business. That would require significant reduction in near term complications, which certainly wouldn't apply to replacing Metformin with any insulin early. Or... showing long term benefits and getting the medical community, ADA, patient advocacy groups, etc. behind it and having patients file lawsuits if necessary. Best to have both a carrot in front and a big stick behind. I don't envy management needing to negotiate with payers. This is probably the toughest nut for management to crack... and I think this is a key area where current management is on a different level than prior (i.e. much higher). It's not a done deal obviously, but I'm at least quite optimistic. BTW, I could say where I'm less thrilled with management... but I'll leave it at that so as to try to fool all those that know I'm getting paid big bucks by Novo to kill Afrezza one small retail proboards investor at a time
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Post by dreamboatcruise on May 18, 2018 0:54:32 GMT -5
ilovekauai... I wish I knew some way to help. I'd suggest connecting with some patient advocacy groups and conveying your results and uncooperative insurance situation. Write, write, write to your insurance. Sad state of affairs when getting opioids is probably easier/cheaper than getting a life extending pharmaceutical. I wish you the best with that. BTW... love your dinner menu... don't take offense, but that sounds very California. I didn't even know what an artichoke was until I moved out here. Now it's one of my favorite things to serve as an appetizer.
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Post by babaoriley on May 18, 2018 0:54:56 GMT -5
Money talks and metfornin costs pennies per day. Insurances companies care more about cost than health. Will reduced complications offset the cost of afrezza? I don't know the answer. Well, there are two routes to get payers to cover. Prove that there is a cost savings over the relatively short time frame they use in their analysis... 3-5 years at best based on what I've gleaned from talking to execs in that business. That would require significant reduction in near term complications, which certainly wouldn't apply to replacing Metformin with any insulin early. Or... showing long term benefits and getting the medical community, ADA, patient advocacy groups, etc. behind it and having patients file lawsuits if necessary. Best to have both a carrot in front and a big stick behind. I don't envy management needing to negotiate with payers. This is probably the toughest nut for management to crack... and I think this is a key area where current management is on a different level than prior (i.e. much higher). It's not a done deal obviously, but I'm at least quite optimistic. BTW, I could say where I'm less thrilled with management... but I'll leave it at that so as to try to fool all those that know I'm getting paid big bucks by Novo to kill Afrezza one small retail proboards investor at a time "I'm getting paid big bucks" - I, for one, would never have said that. But a previous post in this thread, just dripping with disingenuous sentiments. "I hope Kendall isn't too much into hyping how great things already are... I'd hate for him to be embarrassed by the riches before he's actually done the hard work..."
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Post by ilovekauai on May 18, 2018 0:55:07 GMT -5
It's 10:49 pm and just took my final reading. Afrezza now acting like outsilin, as it has already left my body and my BG recalibrated back up to 109 which is ideal for me. I'm curious to see where it is tomorrow morning. How cool this stuff is! I really can't believe it. Now I want a CMG meter with that transdermal patch to get readings all the time and really nail this. Bring it!
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Post by centralcoastinvestor on May 18, 2018 1:28:32 GMT -5
I just tried Afrezza again tonight with supper. My pre-supper BG was 138. I pan fried a 6 oz cut of steak, steamed one artichoke w/olive oil to dip in, one fresh small salad, and some bread, 1/2 orange, and one apricot for dessert. I just did three post-meal testing and sitting at a rock solid BG of 82 right now with no low encountered whatsoever. I did just one 8 unit cartridge for these results. This stuff is wonderful. I only have two 8 unit cartridges left to experiment around with, but think I already got my dose figured out. I really don't need Afrezza during the day. Daily exercise works too and keeps my BG within a normal range, almost. It's the evening hours that I need Afrezza. Anyone out there wanna help me get more Afrezza somehow? Can't believe its come to this. I'm just trying to get my hands on something that really works for my diabetes, like nothing else out there. I would start with calling MannKind Cares to see if they can help you formulate a plan. They have helped many others. And stay focused and persistent.
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Post by Omega on May 18, 2018 1:33:45 GMT -5
Anyone out there wanna help me get more Afrezza somehow? Can't believe its come to this. I'm just trying to get my hands on something that really works for my diabetes, like nothing else out there. Wasn't your Endo willing to write you a script? Just They were "certain" your insurance would deny it? Maybe Mannkind Cares could assist if you get denied?
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Post by sayhey24 on May 18, 2018 5:21:31 GMT -5
I just tried Afrezza again tonight with supper. My pre-supper BG was 138. I pan fried a 6 oz cut of steak, steamed one artichoke w/olive oil to dip in, one fresh small salad, and some bread, 1/2 orange, and one apricot for dessert. I just did three post-meal testing and sitting at a rock solid BG of 82 right now with no low encountered whatsoever. I did just one 8 unit cartridge for these results. This stuff is wonderful. I only have two 8 unit cartridges left to experiment around with, but think I already got my dose figured out. I really don't need Afrezza during the day. Daily exercise works too and keeps my BG within a normal range, almost. It's the evening hours that I need Afrezza. Anyone out there wanna help me get more Afrezza somehow? Can't believe its come to this. I'm just trying to get my hands on something that really works for my diabetes, like nothing else out there. Call Mike and ask to become a "paid" rep for afrezza by offering to do some live demos in exchange for free afrezza. Your first gig could be at ADA giving a live demo in the hall at noon each day. I have this vision of a hi/lo you get on raising you above the crowd with a megaphone announcing a live afrezza demo. I am sure someone will say this is against some rule but sometimes you need to "bend" some rules to move things forward.
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Post by peppy on May 18, 2018 5:25:36 GMT -5
I just tried Afrezza again tonight with supper. My pre-supper BG was 138. I pan fried a 6 oz cut of steak, steamed one artichoke w/olive oil to dip in, one fresh small salad, and some bread, 1/2 orange, and one apricot for dessert. I just did three post-meal testing and sitting at a rock solid BG of 82 right now with no low encountered whatsoever. I did just one 8 unit cartridge for these results. This stuff is wonderful. I only have two 8 unit cartridges left to experiment around with, but think I already got my dose figured out. I really don't need Afrezza during the day. Daily exercise works too and keeps my BG within a normal range, almost. It's the evening hours that I need Afrezza. Anyone out there wanna help me get more Afrezza somehow? Can't believe its come to this. I'm just trying to get my hands on something that really works for my diabetes, like nothing else out there. Denise are you still on your triple therapy?
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Post by sayhey24 on May 18, 2018 5:31:55 GMT -5
ilovekauai - BTW I am serious about calling Mike. Also a couple of fingers of bourbon before bed works wonders for me. I wake up at 85, its pretty amazing.
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Post by mnholdem on May 18, 2018 5:47:19 GMT -5
I recall Joey did that once...and disappeared for about a year. That was when he used a Rip Van Winkle avatar. ;-)
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Post by dreamboatcruise on May 18, 2018 7:24:00 GMT -5
Call Mike and ask to become a "paid" rep for afrezza by offering to do some live demos in exchange for free afrezza. Your first gig could be at ADA giving a live demo in the hall at noon each day. I have this vision of a hi/lo you get on raising you above the crowd with a megaphone announcing a live afrezza demo. I am sure someone will say this is against some rule but sometimes you need to "bend" some rules to move things forward. We can often wish rules bend for us, but it's probably not realistic. Often it's either nuke the rules and live with the good (or bad) consequences, or navigate within the rules. * your success at bending may very I think I may have another prize... for insomnia... yeh!
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