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Post by prcgorman2 on Jun 9, 2019 11:57:42 GMT -5
I like the idea of carrying a BlueHale that measures BG and perhaps tells you it’s opinion of the insulin requirement. A step further would be a device that let you blow through it to get a BG reading, and then inhale an automatically measured amount of Afrezza.
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Post by shawnonafrezza on Jun 9, 2019 12:56:15 GMT -5
Preconception? We aren't talking shots here, just puff the magic dragon. As I stated, provide me with a non invasive CGM (apple watch ect.) And let me watch the food affect on my blood sugar and I too will use the best tool to adust spikes. (Afrezza) I'm not sure how Novo spells it.🙂 The problem is not the shot itself, it's having to take the shot (inhaled or injected). It's compliance burden that is the issue. Part of the problem with T2 is that in the early days there is no visible penalty for non-compliance so there is a low threshold for skipping treatment. If an accurate non-invasive CGM could be built into a watch I think that would be a huge step forward. This cannot be understated. Every action a person has to take is an action. In a book about how/why she built openAPS Dana said this and I think it's really relvent here. Afrezza gives a spoon back to some, but to say it gives back multiple spoons is person dependent. Every action you ahve to take is an action. A puff or a shot, it's the same spoon.
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Post by sportsrancho on Jun 9, 2019 13:01:27 GMT -5
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Post by longliner on Jun 9, 2019 22:34:29 GMT -5
Preconception? We aren't talking shots here, just puff the magic dragon. As I stated, provide me with a non invasive CGM (apple watch ect.) And let me watch the food affect on my blood sugar and I too will use the best tool to adust spikes. (Afrezza) I'm not sure how Novo spells it.🙂 The problem is not the shot itself, it's having to take the shot (inhaled or injected). It's compliance burden that is the issue. Part of the problem with T2 is that in the early days there is no visible penalty for non-compliance so there is a low threshold for skipping treatment. If an accurate non-invasive CGM could be built into a watch I think that would be a huge step forward. I agree, "it's having to take the shot" that is the problem! An inhalation is not a shot, the shot causes the preconception problem, you know blood and all that. Compliance with a inhaler??? No big deal, I spent my youth with an asthmatic who use an inhaler as needed and it was not something of interest, quick discreet, move on.
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Post by shawnonafrezza on Jun 9, 2019 22:39:09 GMT -5
longliner, after 14 years of injections I can promise you it's not the shot. 31g and 4mm isn't a big needle. There are two things, moving to insulin makes a lot of T2 feel like failures (this was greatly discussed at ADA) and having to have an repeatable actionable item. Just think about it, you're sitting here at your desk and your bgl is 120mg/dl. You need to get up, you need to load the dreamboat, you need to inhale. You just had to do all of that and you'd rather just live your life. It's the action, not what the action is. Now rinse and repeat that 5+ times a day.
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Post by longliner on Jun 9, 2019 23:34:24 GMT -5
longliner, after 14 years of injections I can promise you it's not the shot. 31g and 4mm isn't a big needle. There are two things, moving to insulin makes a lot of T2 feel like failures (this was greatly discussed at ADA) and having to have an repeatable actionable item. Just think about it, you're sitting here at your desk and your bgl is 120mg/dl. You need to get up, you need to load the dreamboat, you need to inhale. You just had to do all of that and you'd rather just live your life. It's the action, not what the action is. Now rinse and repeat that 5+ times a day. Shawn, if I am doing that, in conjunction with changing my diet and exercise, when my physician has offered me a very clear choice between type two and not. Understanding that this option will potentially reverse my condition, game on. I watched a relative change diet and exercise with fair success. I ponder if they had combined that with Afrezza, what the outcome may have been. I do understand your position.
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Post by radgray68 on Jun 10, 2019 20:28:51 GMT -5
So...having read the Phil Levin abstract, I kinda would like to see a patient convenience study with a 16, 18 or a 20 unit cartridge. The idea being to get an acceptable result with a one puff, mid-meal scenario for T2's. I know it's exiting to see the sugars going down in the first hour. That's great and all. However, maybe wait til mid-meal, then a larger dose.
I understand why they do the dosing the way they do, for optimal effectiveness, I just also know that convenience sells. Maybe a little less optimal could still beat injections, but simplify the whole thing for patients. Just spit-balling.
Okay, go ahead and let me have it.
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Post by goyocafe on Jun 10, 2019 20:38:14 GMT -5
So...having read the Phil Levin abstract, I kinda would like to see a patient convenience study with a 16, 18 or a 20 unit cartridge. The idea being to get an acceptable result with a one puff, mid-meal scenario for T2's. I know it's exiting to see the sugars going down in the first hour. That's great and all. However, maybe wait til mid-meal, then a larger dose. I understand why they do the dosing the way they do, for optimal effectiveness, I just also know that convenience sells. Maybe a little less optimal could still beat injections, but simplify the whole thing for patients. Just spit-balling. Okay, go ahead and let me have it. www.youtube.com/watch?v=myU81w93Uu4
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Post by shawnonafrezza on Jun 10, 2019 21:07:28 GMT -5
So...having read the Phil Levin abstract, I kinda would like to see a patient convenience study with a 16, 18 or a 20 unit cartridge. The idea being to get an acceptable result with a one puff, mid-meal scenario for T2's. I know it's exiting to see the sugars going down in the first hour. That's great and all. However, maybe wait til mid-meal, then a larger dose. I understand why they do the dosing the way they do, for optimal effectiveness, I just also know that convenience sells. Maybe a little less optimal could still beat injections, but simplify the whole thing for patients. Just spit-balling. Okay, go ahead and let me have it. It's not a bad idea but I can say from experience 2/4/8 I can take and maybe cough on the 8, 12 I almost guarantee I will. I can't imagine a 20.
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Post by prcgorman2 on Jun 11, 2019 6:10:39 GMT -5
shawnflynn, do you do anything special before inhaling such as take a sip of water, or a breathing exercise of any sort? I’ve no medical training but have read about a sip of water from a person who said they were an ENT in Canada, but no idea really whether that is taught or even helps. Just curious. Thank you for posting here. Most of us are eager to learn about the experiences of persons with diabetes and especially Afrezza users.
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Post by shawnonafrezza on Jun 11, 2019 9:36:05 GMT -5
shawnflynn, do you do anything special before inhaling such as take a sip of water, or a breathing exercise of any sort? I’ve no medical training but have read about a sip of water from a person who said they were an ENT in Canada, but no idea really whether that is taught or even helps. Just curious. Thank you for posting here. Most of us are eager to learn about the experiences of persons with diabetes and especially Afrezza users. I do take a sip of water usually. 12U of powder, let alone 20U is a lot of powder.
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Post by rtmd on Jun 11, 2019 12:21:37 GMT -5
How much is a "lot"? Is 12 units like half a teaspoon of powder? A teaspoon?
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Post by goyocafe on Jun 11, 2019 12:33:06 GMT -5
How much is a "lot"? Is 12 units like half a teaspoon of powder? A teaspoon? A defer your question to Tony Montana. He’ll definitely put it in perspective for you.
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Post by harryx1 on Jun 11, 2019 12:40:26 GMT -5
It's amazing what the participants of ADA promote but won't share 1 tweet with Afrezza's results.
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Post by shawnonafrezza on Jun 11, 2019 13:01:02 GMT -5
How much is a "lot"? Is 12 units like half a teaspoon of powder? A teaspoon? No idea. It's 3x more than a 4.
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