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Post by MnkdWASmyRtrmntPlan on Jun 2, 2023 17:43:24 GMT -5
From Figglebird's hotlink:
Abstract
A composition is disclosed comprising glucagon- like peptide 1 (GLP-I) particles in combination with diketopiperazine (DKP) that is stable both in vitro and in vivo. The composition has utility as a pharmaceutical formulation for treating diseases such as diabetes, cancers, and obesity but is not limited to such diseases or conditions. In particularly, the composition has utility as a pharmaceutical formulation for pulmonary delivery.
InventorDavid BrandtWayman Wendell CheathamMary FarisCohava GelberStephanie GreeneMark J. HokensonMark KingAndrea Leone-BayKeith Oberg
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Post by lennymnkd on Jun 2, 2023 18:26:32 GMT -5
What great drug succeeded (modern day ) without commercial advertising.. in a big way ?
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Post by prcgorman2 on Jun 3, 2023 8:41:24 GMT -5
I think Tyvaso DPI might be one, but it depends on your definition of “commercial advertising”. If you literally mean television commercials, I do expect Tyvaso DPI to continue to be successful and become more successful without television advertising. I would some day like to see television commercials for Afrezza, but it might be singular in that I’m not sure I’ve ever seen any TV commercials for any other mealtime insulin, or basal insulin for that matter.
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Post by sportsrancho on Jun 3, 2023 9:56:40 GMT -5
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Post by agedhippie on Jun 3, 2023 10:06:26 GMT -5
What great drug succeeded (modern day ) without commercial advertising.. in a big way ? Advertising drugs is illegal in most countries outside the US so pick any drug where the FDA is being even slower than usual... Metformin has been widely used outside the US since the early 1970s even if it took the FDA another 20 years to approve it in the US. This is not atypical. |
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Post by lennymnkd on Jun 3, 2023 10:59:37 GMT -5
As the FDA goes .. so goes “most countries “ the hard work and commercialization has been done
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Post by lennymnkd on Jun 3, 2023 11:10:15 GMT -5
Produced under license by Bristol-Myers Squibb, Glucophage was the first branded formulation of metformin to be marketed in the U.S., beginning on 3 March 1995. Generic formulations are available in several countries, and metformin is believed to have become the world's most widely prescribed antidiabetic medication.
I bet it was a better investment in 1995
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Post by prcgorman2 on Jun 3, 2023 15:29:08 GMT -5
Sadly, companies that produce metformin might not be a bad investment now. Would an inhalable version of metformin be valuable?
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Post by lennymnkd on Jun 3, 2023 15:40:58 GMT -5
P-man I was referring to 1995 when “marketing began “ 😀
And would love to know if it’s scientifically compatible with TS .FIRST PASS HEPATIC METABOLISM avoidance
Can’t hurt
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Post by agedhippie on Jun 3, 2023 18:26:40 GMT -5
P-man I was referring to 1995 when “marketing began “ 😀 To be clear on that one - marketing began in the US in 1995, but in the rest of the world since at least 1958 (UK launch). It has been the standard of care for Type 2 outside the US since the early 1970s. The GLP-1 drugs are the same - released in Europe in 2011, in the US in 2015. |
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Post by lennymnkd on Jun 4, 2023 9:39:58 GMT -5
How Afrezza is administered and it’s results is a advertising agency’s dream /
Dexcoms add agency could put mannkind on the map …it’s all in the marketing
PILLOWS,cars drugs ..Al said all it would take is the money..
We can continue to be the best keep secret forever without it. That video someone posted
Recently? Juvenile/ Was a great add in itself .. imagine the mass market seeing it !
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Post by prcgorman2 on Jun 4, 2023 9:47:57 GMT -5
FDA constrains what you can say/claim. It’s been years since I researched the FDA rules on Direct To Consumer (DTC) advertising but I’ll just say the FDA is very involved, and picky. If there were no constraints, marketing Afrezza would be easy. But there are lots of constraints, on DTC as well as what representatives and literature can say. It’s not a slam dunk.
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Post by lennymnkd on Jun 4, 2023 10:06:43 GMT -5
Look at what’s being sold out there/ drugs / its all in the disclaimers …
And ours would be mild in comparison..can’t let that stop us ..
A good experienced add agency would work thur using what’s allowed in
A creative way ..semantics…
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Post by cretin11 on Jun 4, 2023 10:16:53 GMT -5
Agree lenny. It’s easy to simply say “the FDA makes it too difficult” but the successful companies don’t let that stop them. Afrezza has so much going for it, a good marketing campaign is most definitely possible (and should’ve already happened).
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Post by lennymnkd on Jun 4, 2023 10:22:30 GMT -5
Even if they have to give up a piece of
The PIE to do it.
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