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Post by mssciguy on Nov 10, 2015 13:01:00 GMT -5
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Post by mssciguy on Nov 10, 2015 13:10:36 GMT -5
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Post by longinvstr on Nov 10, 2015 13:18:28 GMT -5
Okay, Al has a relationship of over 60 years and and a half dozen years involving the US military. No situation more in need for an immediate Rx solution than the battlefield. I like that we have friends in high places ... with weapons |
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Post by mssciguy on Nov 10, 2015 13:29:06 GMT -5
Okay, Al has a relationship of over 60 years and and a half dozen years involving the US military. No situation more in need for an immediate Rx solution than the battlefield. I like that we have friends in high places ... with weapons No doubt. An kind of injectable would be more stable and safer using Technosphere. Military, NASA, EMTs, Doctors without Borders, any kind of remote medical care could use TS. DARPA has traditionally the "head in the clouds" branch of the military that's brought all kinds of practical technologies into our everyday lives. I won't list them here but here's a taste www.alphr.com/features/373546/10-brilliant-darpa-inventions |
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Post by mindovermatter on Nov 10, 2015 13:35:40 GMT -5
No situation more in need for an immediate Rx solution than the battlefield. I like that we have friends in high places ... with weapons No doubt. An kind of injectable would be more stable and safer using Technosphere. Military, NASA, EMTs, Doctors without Borders, any kind of remote medical care could use TS. DARPA has traditionally the "head in the clouds" branch of the military that's brought all kinds of practical technologies into our everyday lives. I won't list them here but here's a taste www.alphr.com/features/373546/10-brilliant-darpa-inventionsNot much use for it if the person is knocked out, unrepsonsive or in shock. But lets wait and see if anything comes of this. At this point, it is all speculation. What TS would be ideal for is vaccinations. Every soldier gets one if not many. What better way to give that than by handing the soldier a pack of color coded inhalers and have him or her inhale the vaccines. |
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Post by mssciguy on Nov 10, 2015 13:37:24 GMT -5
No doubt. An kind of injectable would be more stable and safer using Technosphere. Military, NASA, EMTs, Doctors without Borders, any kind of remote medical care could use TS. DARPA has traditionally the "head in the clouds" branch of the military that's brought all kinds of practical technologies into our everyday lives. I won't list them here but here's a taste www.alphr.com/features/373546/10-brilliant-darpa-inventionsNot much use for it if the person is knocked out, unrepsonsive or in shock. But lets wait and see if anything comes of this. At this point, it is all speculation. "all is speculation" -- truer words have never been spoken. The whole maaaaket is speculation. No guarantees. But this is one hell of a coincidence coming from Matt. |
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Post by sluggobear on Nov 10, 2015 13:54:05 GMT -5
No situation more in need for an immediate Rx solution than the battlefield. I like that we have friends in high places ... with weapons No doubt. An kind of injectable would be more stable and safer using Technosphere. Military, NASA, EMTs, Doctors without Borders, any kind of remote medical care could use TS. DARPA has traditionally the "head in the clouds" branch of the military that's brought all kinds of practical technologies into our everyday lives. I won't list them here but here's a taste www.alphr.com/features/373546/10-brilliant-darpa-inventionsAn obvious use/need for inhaled pain med would be the battlefield. The military currently uses fentanyl lollipops/suckers (maybe morphine too but not sure). While there is not much demand/usage, the military is always over-prepared so a military contract could be quite significant. Beyond the battlefield, severe pain sufferers would clearly benefit from an easily inhaled version of Dilaudid, oxycodone, morphine or fentanyl for breakthrough pain. I don't know the chemistry, pH, size constraints of these molecules but assuming feasibility, PAIN MED might/should have been the first entry into the market for MNKD. But the company wouldn't have been "Mann"kind then I guess. I really do not get all the grousing over supposed management incompetence and personally, I don't see it. The fate of Afrezza is really now in Sanofi's court with insurance (better coverage and losing PA's) and THEN ramping up DTC advertising. I am sure they are having discussions about the chicken and egg problem at Sanofi too. They are not feeling the urgency of financial improvement that Mannkind is feeling though. Logically, I assume they believe insurance coverage precedes demand and I have to defer to their understanding of the problem. And because Sanofi has responsibility for Afrezza success now, the CEO is spending his time and effort on the putative pipeline. The survival and future success as a drug delivery company depend on the next product really. Afrezza's sales will help but not unless they increase 10X very soon. |
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Post by mssciguy on Nov 10, 2015 14:02:42 GMT -5
No doubt. An kind of injectable would be more stable and safer using Technosphere. Military, NASA, EMTs, Doctors without Borders, any kind of remote medical care could use TS. DARPA has traditionally the "head in the clouds" branch of the military that's brought all kinds of practical technologies into our everyday lives. I won't list them here but here's a taste www.alphr.com/features/373546/10-brilliant-darpa-inventionsAn obvious use/need for inhaled pain med would be the battlefield. The military currently uses fentanyl lollipops/suckers (maybe morphine too but not sure). While there is not much demand/usage, the military is always over-prepared so a military contract could be quite significant. Beyond the battlefield, severe pain sufferers would clearly benefit from an easily inhaled version of Dilaudid, oxycodone, morphine or fentanyl for breakthrough pain. I don't know the chemistry, pH, size constraints of these molecules but assuming feasibility, PAIN MED might/should have been the first entry into the market for MNKD. But the company wouldn't have been "Mann"kind then I guess. I really do not get all the grousing over supposed management incompetence and personally, I don't see it. The fate of Afrezza is really now in Sanofi's court with insurance (better coverage and losing PA's) and THEN ramping up DTC advertising. I am sure they are having discussions about the chicken and egg problem at Sanofi too. They are not feeling the urgency of financial improvement that Mannkind is feeling though. Logically, I assume they believe insurance coverage precedes demand and I have to defer to their understanding of the problem. the reason mgmt is a magnet for criticism is simple: They don't deliver on confidence, hype, growth hopes and the usual long list of Bright Shiny Objects brought to you by CNBC. It's part of the game, part of being a publicly owned (well, 60% publicly owned) company. Mgmt executes with technical, medical, regulatory competence but strangely that's not enough. If they would simply pony up a little money to get some legal help on the shorting front, that would SPEAK VOLUMES and enable confidence. For all of the solid science and engineering the company has, the public perception is non-existent to idolatry of Al Mann, to whipping boy and pinata of Wall Street. Like a teenage whiz kid nerd walking down a street full of bullies who want to have some fun and will get every last nickel of lunch money out of the kid. And that's just what they are doing. We could use some transparency about Technosphere. If Sanofi continues their slow, ho-hum roll out with forgettable ads and extremely passive insurance coverage attempts, that's the only other card right now as far as I can tell.... |
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Post by factspls88 on Nov 10, 2015 14:11:23 GMT -5
While I agree the military is a great target for TS and that Al Mann has a long history associated with them, I am having trouble finding links that directly connect MNKD and the military. Maybe I'm just reading things too quickly. Is there an article where it talks directly about a relationship between Mannkind and the military? The link you provide for the earnings report just contains a press release put out by Matt for wide dispersion if I'm not mistaken. |
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Post by liane on Nov 10, 2015 14:12:39 GMT -5
I was thinking along the line of inhaled antidotes for WMD's such nerve gas.
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Post by mssciguy on Nov 10, 2015 14:35:18 GMT -5
I was thinking along the line of inhaled antidotes for WMD's such nerve gas. wakefulness agents are lifesavers, too, like adderall and others. Can't get an effect any faster than by inhalation if I am not mistaken. |
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Post by dreamboatcruise on Nov 10, 2015 14:56:56 GMT -5
I've been involved in several DARPA programs over the years. There is a LOT of overhead hassle in dealing with FAR/DFAR/DCAA/DCMA regulations and oversight. If you can get money to help fund something that has commercial potential then certainly it can be worth the hassle and a good source of non-dilutive funding. Often times what DARPA funds still leaves a large development gap before the "real" military will procure.
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Post by Deleted on Nov 10, 2015 15:14:15 GMT -5
I was thinking along the line of inhaled antidotes for WMD's such nerve gas. What about taking the over the counter product like this and putting on Technosphere? These are anti-radiation pills? www.anbex.com |
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Post by mssciguy on Nov 10, 2015 15:46:37 GMT -5
I was thinking along the line of inhaled antidotes for WMD's such nerve gas. What about taking the over the counter product like this and putting on Technosphere? These are anti-radiation pills? www.anbex.comThat's extremely clever. Might be great for incident responders for example. Matt and Hakan said that the phone lines are open. Why not bounce it off them? (might want to search patents at uspto first). For some reason another one just came to mind upon seeing your idea, how about anti-venoms for spiders, snakes, etc. How about antibiotics for Lyme disease, if you get bitten by a tick? Epinephrine for bee stings would be good too (usually the patient is still breathing). Do we have a place on this board where Technosphere application ideas are discussed @liane mnholdem -- maybe locked for members only? Enough ideas and maybe we'll achieve critical mass for an irreversible stock price explosion  |
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Post by trondisc on Nov 10, 2015 18:41:56 GMT -5
Pain management for the military on the battlefield using inhalation treatment is not only intriguing but VERY promising considering the outdated forms of popping pills and administering shots. Does anyone think this is a long shot happening or could this partnership with the USA military (or abroad?) actually materialize next year for an announcement?
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