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Post by mnholdem on Dec 29, 2015 12:36:53 GMT -5
Basically, my dream is the realization of everything MannKind Corporation lists at their website under Technosphere's Capabilities:
Source: www.mannkindtechnologies.com/Capabilities.aspx
Dry powder, device and advanced development technologies are uniquely integrated at MannKind to enable real world translational medicine. We strive to get medicinal concepts rapidly progressed into sensible, patient-friendly treatment solutions.
Inhaled drug delivery provides many benefits, including:
•Rapid onset of action
•Avoidance of first pass metabolism
•Needle-free administration for systemic or local drug effect
These are important differentiators within the growing market of self-administered medicines. Application for our MannKind technologies exists in many areas, and we are seeking collaborative interest from the medical industry to create new opportunities for treatment of:
•Pain
•Migraine
•Anti-nausea
•Anti-obesity
•Osteoporosis
•GI disorder
•Pulmonary arterial hypertension
•Diabetes
•Immunosuppression
•Vaccination
•Respiratory disorder
•Adjuvant therapy
•Reconstituted powders
---
Is that too much to ask?
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Post by Deleted on Dec 29, 2015 12:53:08 GMT -5
It's already been stated that a TS application for ED would cause a precipitous drop in blood pressure due to the rapid onset. I'm not saying they could not overcome this obstacle, but it's not as simple as loading Viagra on to TS. Maybe a lower dose or a means of slowing down the action would work. It would be very cool if they have been working on this in stealth mode while everyone thinks it can't happen, and then - boom - we have an ED application. Apricus has a topical ED approved in the EU and will be applying for FDA at some point so I don't think TS would be a good us of funds for ED. |
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Post by suebeeee1 on Dec 29, 2015 13:01:19 GMT -5
It's already been stated that a TS application for ED would cause a precipitous drop in blood pressure due to the rapid onset. I'm not saying they could not overcome this obstacle, but it's not as simple as loading Viagra on to TS. Maybe a lower dose or a means of slowing down the action would work. It would be very cool if they have been working on this in stealth mode while everyone thinks it can't happen, and then - boom - we have an ED application. Apricus has a topical ED approved in the EU and will be applying for FDA at some point so I don't think TS would be a good us of funds for ED. It is ALL about speed when it comes to ED treatment. Unless he is planning on having sex, and takes ED treatment at east 1/2 hour in advance, it just doesn't work! Guy at a bar with his buddies, not planning on having sex and not prepared, is hit upon by hot woman. What is he to do???. JUST BREATHE! I can see the commercials now! |
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Post by silentknight on Dec 29, 2015 14:31:51 GMT -5
It's already been stated that a TS application for ED would cause a precipitous drop in blood pressure due to the rapid onset. I'm not saying they could not overcome this obstacle, but it's not as simple as loading Viagra on to TS. Maybe a lower dose or a means of slowing down the action would work. It would be very cool if they have been working on this in stealth mode while everyone thinks it can't happen, and then - boom - we have an ED application. Apricus has a topical ED approved in the EU and will be applying for FDA at some point so I don't think TS would be a good us of funds for ED. Do patients experience rigid fingers or experience loss of functionality of their hands or extremities after applying the topical solution? If not, I'd call bs on its efficacy.  I still think I'd rather take a puff off of a Dreamboat that have to smear a cream. I guess the same could be said for Afrezza vs subcutaneous insulin but that hasn't proved to be as sought after as we'd hoped either. |
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Post by babaoriley on Dec 29, 2015 14:49:20 GMT -5
An energy booster would be nice, but likely would be abused by overuse.
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Post by kball on Dec 29, 2015 17:06:42 GMT -5
Epilepsy. Tremors. Anxiety.*** Chronic Fatigue.*** GI (diarreah/constipation). Arthritis. Seasonal allergies.*** Cough suppressant. Stop smoking aid.*** Fantastic list imo...have no idea the practicality of any of them. Hoping one day |
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Post by derek2 on Dec 29, 2015 17:34:52 GMT -5
1. Antiemetic - when you're nauseous you often can't keep down oral meds.
2. Migraine - the quicker onset, the better.
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Post by mssciguy on Dec 29, 2015 17:54:19 GMT -5
An energy booster would be nice, but likely would be abused by overuse. Funny you mentioned that one. I worked on an "eliquid" a few years ago (for ecigarettes) and tried to do what tobacco companies did many years ago with incorporating MAOi's and other things to give cigarettes such addictive qualities. Canned the project mid stream because I tried this stuff and was feeling very very very good at 2, 3 am... client was not happy that I pulled the plug. Would have been disaster. Your intuitions are spot on. If anyone is interested in the crap tobacco companies have pulled in the past, UCSF has a huge document repository. Makes Wall Street look like... just another evil big corporate swindle. |
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Post by suebeeee1 on Dec 29, 2015 18:13:46 GMT -5
An energy booster would be nice, but likely would be abused by overuse. Funny you mentioned that one. I worked on an "eliquid" a few years ago (for ecigarettes) and tried to do what tobacco companies did many years ago with incorporating MAOi's and other things to give cigarettes such addictive qualities. Canned the project mid stream because I tried this stuff and was feeling very very very good at 2, 3 am... client was not happy that I pulled the plug. Would have been disaster. Your intuitions are spot on. If anyone is interested in the crap tobacco companies have pulled in the past, UCSF has a huge document repository. Makes Wall Street look like... just another evil big corporate swindle. One begins to worry about capitalism as a wall but then I remember I've owned a few successful businesses in my life that didn't look like that at all! |
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Post by mssciguy on Dec 29, 2015 18:22:48 GMT -5
Funny you mentioned that one. I worked on an "eliquid" a few years ago (for ecigarettes) and tried to do what tobacco companies did many years ago with incorporating MAOi's and other things to give cigarettes such addictive qualities. Canned the project mid stream because I tried this stuff and was feeling very very very good at 2, 3 am... client was not happy that I pulled the plug. Would have been disaster. Your intuitions are spot on. If anyone is interested in the crap tobacco companies have pulled in the past, UCSF has a huge document repository. Makes Wall Street look like... just another evil big corporate swindle. One begins to worry about capitalism as a while but then I remember I've owned a few successful businesses in my life that didn't look like that at all! I hear you! Right now, I just do high end skin care formulations. I want to stay small, know my customers. The last thing in the world would be to sell out! Maybe the real secret is to stay out of debt, and not be hostage to dark forces of banking or Wall Street. Money is almost free right now but that's going to change quickly. Suebeee you would probably one of the businesses that I interact with. But these past few years, with all the free money around, there's been a lot of selling below production costs by many for various reasons. It will change quickly. |
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