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Post by nylefty on Jun 14, 2017 14:46:52 GMT -5
Can anyone confirm this? Aloha96707 Wednesday, 06/14/17 10:34:26 AM Re: Hypi post# 24134 Post # of 24138 I heard from friend that VDEX is writing about 300 scripts a month. With every new patient they attached a CGM for a week and monitor their BG Levels and their diet. They give them samples with strict instructions so that they can see how the patient reacts. After the first week they will adjust. It's a smart way to ease the patient on to Afrezza and for the patient to understand Afrezza. Re: VDEX is writing about 300 scripts a month. I find that hard to believe... First off, our sales force would have to have had a negative impact on Afrezza's script counts. It's hard to imagine they're that incompetent... And second, I don't think 300 is physically possible with only one location. Afrezza is only targeting a relatively small portion of the diabetes population. Given that, VDEX would have to be swamped with patents.... they'd have opened another location by now. I think VDEX writing 300 Afrezza scripts total (since they opened) would be more reasonable. I highly doubt that it's 300 scripts a month -- but let's remember that the numbers we see every Friday are only estimates, based on what is supposedly a representative sample of pharmacies. If VDex patients aren't going to any of those pharmacies their scripts won't show up in the Symphony numbers.
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Post by casualinvestor on Jun 14, 2017 14:47:44 GMT -5
Can anyone confirm this? Aloha96707 Wednesday, 06/14/17 10:34:26 AM Re: Hypi post# 24134 Post # of 24138 I heard from friend that VDEX is writing about 300 scripts a month. With every new patient they attached a CGM for a week and monitor their BG Levels and their diet. They give them samples with strict instructions so that they can see how the patient reacts. After the first week they will adjust. It's a smart way to ease the patient on to Afrezza and for the patient to understand Afrezza. Re: VDEX is writing about 300 scripts a month. I find that hard to believe... First off, our sales force would have to have had a negative impact on Afrezza's script counts. It's hard to imagine they're that incompetent... And second, I don't think 300 is physically possible with only one location. Afrezza is only targeting a relatively small portion of the diabetes population. Given that, VDEX would have to be swamped with patents.... they'd have opened another location by now. I think VDEX writing 300 Afrezza scripts total (since they opened) would be more reasonable. 300/month = 70/week. I could believe something like: They try Afrezza on 300 people per month. All of those might be going on samples first, and not all (not many?) move on to monthly scripts. I'm sure VDEX has good access to samples. IIRC, there was some talk at the ASM or the quarterly meeting about transitioning the samples to coupons so they could be tracked in the script counts As for your second point, I have no idea how large a staff VDEX has, or how many appt each nurse/doc has in a week. I'm sure they have several doctors and NPs
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Post by peppy on Jun 14, 2017 14:50:10 GMT -5
What VDEX could have going for it, is word of mouth.
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Post by kbrion77 on Jun 14, 2017 14:52:31 GMT -5
Re: VDEX is writing about 300 scripts a month. I find that hard to believe... First off, our sales force would have to have had a negative impact on Afrezza's script counts. It's hard to imagine they're that incompetent... And second, I don't think 300 is physically possible with only one location. Afrezza is only targeting a relatively small portion of the diabetes population. Given that, VDEX would have to be swamped with patents.... they'd have opened another location by now. I think VDEX writing 300 Afrezza scripts total (since they opened) would be more reasonable. I highly doubt that it's 300 scripts a month -- but let's remember that the numbers we see every Friday are only estimates, based on what is supposedly a representative sample of pharmacies. If VDex patients aren't going to any of those pharmacies their scripts won't show up in the Symphony numbers. And they certainly aren't showing up in quarterly revenues.......
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Post by peppy on Jun 14, 2017 15:04:53 GMT -5
I hear you. not in quarterly's. HUGE IF, then when? I am old now. When I was young, I remember westerns on the television. I remember how stampede's were depicted in the western. So if it is true, with VDEX, you can get afrezza, and a week continuous glucose monitoring, and there is an associated coaching program, then if, and they help you with insurance, also as nylefty pointed out, I believe I read, you can get the afrezza at vdex, then.... when does it become a stampede?
Molly type one, had a father who was type one and a sister, who is type one.
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Post by scoy on Jun 14, 2017 15:11:31 GMT -5
VDEX recently had a grand opening at a larger location That's one good sign. Opening brand new locations elsewhere would be an excellent sign that if the horses are not immediately stampeding, at least they've woken up.
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Post by nylefty on Jun 14, 2017 15:13:50 GMT -5
just throwing it out in the atmosphere, I thought I read vdex opened another location, was it @ 3 weeks ago I read it? Am I incorrect? You're incorrect. They moved from one location (where they had been sharing space) to another location. Here's what they posted on Facebook: Vdex Diabetes May 19 at 12:15pm ·
We are pleased to announce the opening of our new dedicated facility in Canoga Park where previously we had an office share arrangement. With this new medical facility we will be able to deliver a higher standard of care, and better help patients manage their diabetes.
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Post by madog365 on Jun 14, 2017 15:15:04 GMT -5
I will teach you all a life lesson for free. Never EVER believe a word posted on IHub.
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Post by sportsrancho on Jun 14, 2017 15:25:13 GMT -5
just throwing it out in the atmosphere, I thought I read vdex opened another location, was it @ 3 weeks ago I read it? Am I incorrect? You're incorrect. They moved from one location (where they had been sharing space) to another location. Here's what they posted on Facebook: Vdex Diabetes May 19 at 12:15pm ·
We are pleased to announce the opening of our new dedicated facility in Canoga Park where previously we had an office share arrangement. With this new medical facility we will be able to deliver a higher standard of care, and better help patients manage their diabetes. We know they needed more space. If their business has picked up in the last 3 weeks and they are holding these patients hands the samples will turn into scripts but will not have showed up yet.
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Post by peppy on Jun 14, 2017 15:28:12 GMT -5
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Post by zuegirdor on Jun 14, 2017 16:15:18 GMT -5
I hear you. not in quarterly's. HUGE IF, then when? I am old now. When I was young, I remember westerns on the television. I remember how stampede's were depicted in the western. So if it is true, with VDEX, you can get afrezza, and a week continuous glucose monitoring, and there is an associated coaching program, then if, and they help you with insurance, also as nylefty pointed out, I believe I read, you can get the afrezza at vdex, then.... when does it become a stampede? Molly type one, had a father who was type one and a sister, who is type one. Hahaha! western's on television, simpler times I remember too....Gunsmoke, Have Gun Will Travel, Cheyenne. There was Wagon Train, Sugarfoot, Bat Masterson, for some of the more obscure. Then Bonanza, Wild Wild West, The Rifleman rounding out with High Chapparell in transition to more modern versions.
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Post by sportsrancho on Jun 14, 2017 16:36:08 GMT -5
I hear you. not in quarterly's. HUGE IF, then when? I am old now. When I was young, I remember westerns on the television. I remember how stampede's were depicted in the western. So if it is true, with VDEX, you can get afrezza, and a week continuous glucose monitoring, and there is an associated coaching program, then if, and they help you with insurance, also as nylefty pointed out, I believe I read, you can get the afrezza at vdex, then.... when does it become a stampede? Molly type one, had a father who was type one and a sister, who is type one. Hahaha! western's on television, simpler times I remember too....Gunsmoke, Have Gun Will Travel, Cheyenne. There was Wagon Train, Sugarfoot, Bat Masterson, for some of the more obscure. Then Bonanza, Wild Wild West, The Rifleman rounding out with High Chapparell in transition to more modern versions. Rawhide was my fave. And Fury for the horse lovers.
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Post by brotherm1 on Jun 14, 2017 16:47:35 GMT -5
The Virginian, The Cisco Kid, and my favorite, the Go Go Gophers.
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Post by agedhippie on Jun 14, 2017 16:53:49 GMT -5
Is there a scientific explanation for "insulin resistance" or is this theory similar to "pancreatic phase response"? My endo told me that Insulin resistance is reversible. It is caused by inactivity. Get active. Stay active. However, your pancreas's capacity to deliver insulin is genetically pre-determined. Use it slow or use it fast by eating more or less carbs per meal. You will only have so much insulin to secrete over your lifetime. Possible exception is that there is some evidence that "starvation mimicking" diets can regenerate beta cells in the pancreas. It is partially reversible. Weight loss will do it, as will metformin to a degree, and TZDs. The idea that only have so much insulin to secrete over your lifetime is wrong though. Your beta cells are continually dying off and being replaced with fresh cells (as are all your cells). The issue for Type 2 diabetics are that they are not being replaced as fast as they are dying off - this is not an issue with non-diabetics though.
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Post by zuegirdor on Jun 14, 2017 18:30:49 GMT -5
My endo told me that Insulin resistance is reversible. It is caused by inactivity. Get active. Stay active. However, your pancreas's capacity to deliver insulin is genetically pre-determined. Use it slow or use it fast by eating more or less carbs per meal. You will only have so much insulin to secrete over your lifetime. Possible exception is that there is some evidence that "starvation mimicking" diets can regenerate beta cells in the pancreas. It is partially reversible. Weight loss will do it, as will metformin to a degree, and TZDs. The idea that only have so much insulin to secrete over your lifetime is wrong though. Your beta cells are continually dying off and being replaced with fresh cells (as are all your cells). The issue for Type 2 diabetics are that they are not being replaced as fast as they are dying off - this is not an issue with non-diabetics though. Right, so what do endos know anyway. But my endo may be on to something with the more or less predetermined pancreatic insulin life expectancy if you think about the oxygen demand of the pancreas, vascular and other structural maintenance that has to compete with aging and everyday abuse...it would seem that many, especially non-obese type 2s simply outlive their beta cells (ie its not really the insulin resistance that gets them in the end) The debate about beta cell regeneration goes on. Faustman notes that mice regenerate readily. But that has not been the conventional assumption for people. The speak of needing some trick or compound. And even then it appears you may only be able to convert alpha cells to betas, which means you will have fewer alphas-whatever that implies for your health. Faustman was one of first to note residual insulin and its potential importance if the auto-immune system can be reset by BCG vaccine. She is hopeful that BCG may also facilitate some beta cell regeneration-by what process I don't think they have said (or know of) yet. My fingers and toes are crossed!! Want somewhere else to "invest" your money? They take donations.
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