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Post by sportsrancho on Jun 15, 2017 9:08:31 GMT -5
Regardless of when we first heard of VDex it's obvious it was in the planning stages far before Sanofi announced its separation. So I think the point of this discussion was that some creditors backed out when Sanofi left could still be feasible. I'm happy to hear Vdex is doing well and 300 new on Afrezza samples per month sounds great I hope to see them turning to real scripts soon. Hopefully we will see a modest script increase tommorow this is turning into a bad week because of last weeks script report. We need script numbers up and news on getting finances to increase our runway very soon to help our suffering stock price.. July is coming and I'm hoping for fireworks with MNKD. [ This is correct ( was in planning before SNY dumped us ) all correct:-) |
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Post by bioexec25 on Jun 16, 2017 8:29:38 GMT -5
Was just on the Vdex site. If you haven't been on recently you may want to check it out. Looking good and check out the Testimonials. There are four videos that really get into some great details on issues and the simplicity and efficacy of Afrezza. www.vdexdiabetes.com. Btw, mannkindcorp.com really improving as well both in style and substance. I know maybe it's only me not noticing these improvements. ;-) |
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Post by Deleted on Jun 16, 2017 8:48:39 GMT -5
How many scripts is this place contributing? They have to be losing money each month
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Post by ripano on Jun 16, 2017 9:24:14 GMT -5
Good question, unfortunately no one seems to have a real update on VDEX sales.
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Post by MnkdWASmyRtrmntPlan on Jun 16, 2017 11:28:48 GMT -5
If VDEX has a direct channel with MNKD, perhaps they buy in quantity and keep a large stockpile (like the boat-load shipped to UAE ;o). JK, but if so (on a much smaller scale), MNKD would not know their individual New Rx sales.
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Post by sla55 on Jun 17, 2017 6:39:36 GMT -5
On VDEX Diabetes Facebook Page:
Vdex Diabetes
10 hrs ·
The Myth of Prediabetes
You’ve just come from the doctor’s office where you got the news that you’re prediabetic. Whew. That was close. You’re glad. Blood sugar’s a little high but at least you’re not “diabetic.” Your eating’s been a little less disciplined that you’d like. You’ll clean that up. You were worried. But, you’re feeling better now.
Uh…no.
“Prediabetes” is a label. Just like “Fresh Frozen” which appears sometimes on seafood. What is “fresh frozen” anyway? Is it fresh or not? Clearly it’s frozen. How can it be fresh and frozen? … Word games. That’s what this is. We see them all the time. And, it’s one thing to see them in the meat or produce section of your supermarket, but quite another to see them in the diagnosis of disease.
One doctor, commenting on the term “prediabetes,” says it’s a term probably invented by a doctor trying to clear patients out of his waiting room. Maybe so. But what does it mean? Simply stated, prediabetes means that you’re blood sugar control is outside of the normal range, but below the number set as the formal diagnosis of diabetes. In other words, it’s early stage diabetes. Or, let’s quit with the word games entirely and call it what it is: diabetes.
Patients derive a great deal of comfort in finding themselves in the prediabetes category rather than diabetes. They shouldn’t. They should be highly concerned that they have abnormal blood sugar control. It almost certainly will get worse. It’s important to remember that the exact point of abnormality that we call “diabetes” is itself somewhat arbitrary. With an HbA1c reading of 6.4 a person is prediabetic, but with a reading of 6.5 he or she is now diabetic. This is absurd.
In one study, researchers found that upon first diagnosis of type 2 diabetes, patients had already lost 80% of their beta cell function. That means a lot of damage has been done before diagnosis. In another study, it was determined that beta cells had lost 50% of their volume in the prediabetes range. Clearly, there is a lot of dysfunction and damage when blood sugar begins to show abnormality, but before the formal diagnosis of diabetes.
As with all disease, prevention or at least, early intervention is critical to the best outcomes. Diabetes is no different. Early intervention can change the course of the disease, and hence, your life. Don’t wait. Don’t be comforted to hear you’re “prediabetic.” Do something immediately because if you don’t, the situation will only get worse.
The best way to think about “prediabetes” is how we think about a “pre-owned” car. We definitely don’t think that car is new, despite what the term implies. It’s used. It’s got wear and tear on it. So does your pancreas when you’re “prediabetic.”
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Post by falconquest on Jun 17, 2017 9:07:37 GMT -5
On VDEX Diabetes Facebook Page: Vdex Diabetes 10 hrs · The Myth of Prediabetes You’ve just come from the doctor’s office where you got the news that you’re prediabetic. Whew. That was close. You’re glad. Blood sugar’s a little high but at least you’re not “diabetic.” Your eating’s been a little less disciplined that you’d like. You’ll clean that up. You were worried. But, you’re feeling better now. Uh…no. “Prediabetes” is a label. Just like “Fresh Frozen” which appears sometimes on seafood. What is “fresh frozen” anyway? Is it fresh or not? Clearly it’s frozen. How can it be fresh and frozen? … Word games. That’s what this is. We see them all the time. And, it’s one thing to see them in the meat or produce section of your supermarket, but quite another to see them in the diagnosis of disease. One doctor, commenting on the term “prediabetes,” says it’s a term probably invented by a doctor trying to clear patients out of his waiting room. Maybe so. But what does it mean? Simply stated, prediabetes means that you’re blood sugar control is outside of the normal range, but below the number set as the formal diagnosis of diabetes. In other words, it’s early stage diabetes. Or, let’s quit with the word games entirely and call it what it is: diabetes. Patients derive a great deal of comfort in finding themselves in the prediabetes category rather than diabetes. They shouldn’t. They should be highly concerned that they have abnormal blood sugar control. It almost certainly will get worse. It’s important to remember that the exact point of abnormality that we call “diabetes” is itself somewhat arbitrary. With an HbA1c reading of 6.4 a person is prediabetic, but with a reading of 6.5 he or she is now diabetic. This is absurd. In one study, researchers found that upon first diagnosis of type 2 diabetes, patients had already lost 80% of their beta cell function. That means a lot of damage has been done before diagnosis. In another study, it was determined that beta cells had lost 50% of their volume in the prediabetes range. Clearly, there is a lot of dysfunction and damage when blood sugar begins to show abnormality, but before the formal diagnosis of diabetes. As with all disease, prevention or at least, early intervention is critical to the best outcomes. Diabetes is no different. Early intervention can change the course of the disease, and hence, your life. Don’t wait. Don’t be comforted to hear you’re “prediabetic.” Do something immediately because if you don’t, the situation will only get worse. The best way to think about “prediabetes” is how we think about a “pre-owned” car. We definitely don’t think that car is new, despite what the term implies. It’s used. It’s got wear and tear on it. So does your pancreas when you’re “prediabetic.” I can comment on your "fresh frozen" comment sla. Food producers use a process called IQF or individual quick freeze where products (fruit, shrimp etc.) are washed and then separated on a conveyor so they are not touching each other and quick frozen very rapidly under extremely cold temperatures. You really can't do better than IQF unless you consume the product right from the plant. In absence of being able to have a piece of fresh fruit, IQF is the next best thing. I get what you're saying though, there is the term pre-cancerous that is used as well, so is that analogous to being a almost pregnant? |
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Post by mnholdem on Jun 17, 2017 9:30:43 GMT -5
Falcon, don't you think your analogy of pregnancy could be replaced with something better? One is either pregnant or not. Black or white. Yes or no. Pre-diabetes v diabetes does not carry that distinction because the BG measurements are in a range. The author's point is that in the range of fresh to stale/rotten, quick-frozen is as close to fresh as one can get. When a woman worrying about an unplanned/unwanted pregnancy learns she is not pregnant, she can say, "Whew! That had me worried!" and that's that. But when a patient is told they are pre-diabetic, it's nothing you should feel relieved about.  |
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Post by agedhippie on Jun 17, 2017 9:53:00 GMT -5
Patients derive a great deal of comfort in finding themselves in the prediabetes category rather than diabetes. They shouldn’t. They should be highly concerned that they have abnormal blood sugar control. It almost certainly will get worse. It’s important to remember that the exact point of abnormality that we call “diabetes” is itself somewhat arbitrary. With an HbA1c reading of 6.4 a person is prediabetic, but with a reading of 6.5 he or she is now diabetic. This is absurd. In one study, researchers found that upon first diagnosis of type 2 diabetes, patients had already lost 80% of their beta cell function. That means a lot of damage has been done before diagnosis. In another study, it was determined that beta cells had lost 50% of their volume in the prediabetes range. Clearly, there is a lot of dysfunction and damage when blood sugar begins to show abnormality, but before the formal diagnosis of diabetes. That same comfort that people find in being pre-diabetic is the same reason people put off going on insulin. They have been told for so long that insulin is the end of the road that to go on insulin means that they have to completely accept that this is never going away and that they have to deal with it. That's a big jump so people try to avoid it for as long as possible. Interestingly the US has one of the worst records for putting people on insulin just beating out India. The numbers I always saw for diabetes was 40% loss made you diabetic if you were lean (60% if you are overweight). Both are guesses really because you cannot measure beta cell mass other than by autopsy (people are amazingly reluctant to donate their pancreas while they still need it - no thought for science  ) |
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Post by falconquest on Jun 18, 2017 12:12:20 GMT -5
Falcon, don't you think your analogy of pregnancy could be replaced with something better? One is either pregnant or not. Black or white. Yes or no. Pre-diabetes v diabetes does not carry that distinction because the BG measurements are in a range. The author's point is that in the range of fresh to stale/rotten, quick-frozen is as close to fresh as one can get. When a woman worrying about an unplanned/unwanted pregnancy learns she is not pregnant, she can say, "Whew! That had me worried!" and that's that. But when a patient is told they are pre-diabetic, it's nothing you should feel relieved about. mn, My comments were directed more toward crazy terminology than specifics about pre-diabetes. I certainly understand the distinction. Some afflictions are a matter of degree while others are black and white. I have read information criticising the term "pre-cancerous" which (without going into a scientific discussion) is more black and white (hence the pregnancy analogy) versus something that is a matter of degrees such as pre-diabetes or Alzheimers. So just commenting on terminology vs a specific diagnosis. |
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Post by mnholdem on Jun 18, 2017 13:43:56 GMT -5
Okay. I simply couldn't make the prenancy analogy work, although even there a close call may, like pre-diabetes, may require some changes in behavior. That, of course, is a dad talking.  |
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Post by myocat on Jun 19, 2017 8:15:07 GMT -5
Seeking Alpha guy said last week scripts creep up above 300.
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Post by ripano on Jun 23, 2017 14:27:58 GMT -5
Is anyone in touch with Vdex ?
Any news about how afrezza is being marketed , prescribed etc ?
Is NO news GOOD news ?
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Post by peppy on Jun 23, 2017 16:40:52 GMT -5
Is anyone in touch with Vdex ? Any news about how afrezza is being marketed , prescribed etc ? Is NO news GOOD news ? I have seen mannmade name on the board. He knows what is going on. I hope it is all good. actually, it may be vdex helping afrezza script dump.
vdex and sports.
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Post by sla55 on Jun 23, 2017 18:44:33 GMT -5
On VDEX Diabetes Facebook Page:
How Serious is Diabetes Really?
There’s a story, perhaps apocryphal, of a presentation by a group of physicians to an audience of patients. A doctor polls the audience, asking the patients which disease they would prefer to have, HIV or diabetes. The entire audience raises their hand for diabetes. The doctor then polls the group of physicians and every doctor raises their hand for HIV. The point: those who know, know diabetes is more fearsome than HIV.
This story really captures one of the biggest problems with diabetes care today: people don’t realize how serious the disease really is. While we hear a lot about diabetes in the media, we don’t hear a lot about people dying from diabetes. The reports of death are usually of other conditions… But, those conditions either were caused, or exacerbated, by diabetes.
Take the case of the recent death in April of this year of comedian, Don Rickles. It was widely reported the he died of kidney failure. Much less widely reported was that he was also a Type 2 diabetic. What is the leading cause of kidney failure? Diabetes. This doesn’t mean that diabetes was the culprit in Rickles death, but it should be strongly suspected. Why? Because most of the other causes that can lead to kidney failure, like high blood pressure are more easily controlled with medication than is diabetes.
We often focus on the most proximate cause, in Rickles case, kidney failure. But, kidney failure is the expression of diabetes. Think about it this way: a person steps in front of a bus, gets hit and bleeds to death. Is his death caused by bleeding to death? Well, yes, but the bus had something to do with it. In fact, it had everything to do with it. Diabetes is the bus in many cases, and yet the explanation that gets the focus is the bleeding.
The same phenomenon occurs with strokes and heart disease. Each may be the proffered explanation for death, but the question really should be, what caused the stroke and heart disease? Diabetics have a much higher incidence of both. This is also true of cancer.
So, why is diabetes so deadly? The answer is interesting and counterintuitive: diabetes is so deadly because it doesn’t seem so. Nobody really dies immediately from diabetes. Early stage diabetes is often undiagnosed. High blood sugar for a day, a week, even a year, won’t kill you. But many years of it almost certainly will. But, the death likely won’t even be blamed on diabetes. The killer could be so many different issues, but the cause is the same.
Going back to HIV, it got a lot of attention because HIV was rightly seen as a killer, which it is. HIV sufferers often died from pneumonia, but people understood that the pneumonia only proved deadly because those people had HIV. It’s almost the opposite situation with diabetes: people don’t see it as a killer and the complications, like kidney failure or cardiac disease, are rightly perceived as deadly. So diabetes doesn’t induce the fears in people that something like HIV does. But, as the story above illustrates, among those who know, it does.
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