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Post by itellthefuture777 on Jul 30, 2017 3:37:19 GMT -5
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Post by itellthefuture777 on Jul 30, 2017 3:44:35 GMT -5
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Post by sportsrancho on Jul 30, 2017 5:32:22 GMT -5
Stephanie Chaparro Jul 18 from Android
20something with T1D
Has anyone here ever tried the inhaled insulin?
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Cindy Goddard Jul 18 from iOS
Yes I have tried the inhaled insulin. I absolutely loved it! You can take it right before you eat without waiting and only stays in your body for 1 hour. I used it for snacks before bed so I didn't have to worry about insulin in board while I was asleep. I also used it for snacks during the day so I wouldn't still have insulin on board before a meal. I was still on the pump. However I could not take the side effects. It gave me a horrific smokers cough that sounded nasty. I would cough all night and throughout the day. And I didn't even use it full time. I also only used it for 3 months. It took 2 months after I stopped before the cough finally went away. My brother uses it for every meal and uses a long acting shot once a day. He loves it and has no problems.
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Allan Hodder Jul 18 from iOS
Adult with T1D
I know someone who has tried inhaled insulin. Apparently it worked very quickly and it's effects lasted about 2 hours so it was great for correcting a high BG.. I'd consider trying it if it were available, but I've never asked about it for myself. Would definitely like to have the opportunity to try it.
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William Bennett Jul 18
Adult with T1D
Re Afrezza: there's been much discussion of it on TUD by people who love it. To my mind the thing that always gets stressed here and elsewhere--no "ouch"!--is far less important than the fact that it acts and clears so quickly. Not sure why there's as much resistance to it as there seems to be. From what I've read from actually users the drawbacks (lung irritation) are not universal: some people stopped using for that reason but many others have no such problem and swear by it. My own endo was reluctant when I asked about it and I haven't pushed about it but I am curious. Seems like it really works to flatten spikes without causing lows.
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Allison S. Jul 18 from iOS
Adult with T1D
I too was wondering about the inhaled insulin- I'm glad you all posted your responses were very informative. I also learned something new didn't know about the Medtronic I port.
Hopefully in time there will be a cure and we won't have to use any of these things anymore
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Rebecca Hamill Jul 19
This was really informative!!!! Thanks, there's a few things I'll be asking about at my next visit
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Steve Carter Jul 19
Fabulous, thanks
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Post by liane on Jul 30, 2017 6:02:25 GMT -5
itellthefuture777, It would be best if you start separate threads for differing topics. It gets very confusing if people respond to different topics within 1 thread. I'm just trying to keep the board organized. If it's a link to an article, best to put it in the "Articles" section.
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Post by brotherm1 on Jul 30, 2017 6:42:40 GMT -5
I wonder how many have the persistent cough issue with Afrezza that Cindy reportedly has. I wonder if it has something to do with the Ph of Afrezza meant to match the Ph of normal lungs? Could this persistent cough with Afrezza be caused by an acidosis, perhaps a diabetic acidosis, for example, that is caused by poorly regulated blood glucose levels?
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Post by sportsrancho on Jul 30, 2017 7:19:37 GMT -5
I wonder how many have the persistent cough issue with Afrezza that Cindy reportedly has. I wonder if it has something to do with the Ph of Afrezza meant to match the Ph of normal lungs? Could this persistent cough with Afrezza be caused by an acidosis, perhaps a diabetic acidosis, for example, that is caused by poorly regulated blood glucose levels? Good question. 20% I believe... Outside of insurance it's the only problem. Dosing is getting so much better! T1 and T2's. Clearly not a niche drug. Superior to all others. In time 50 to 80% of the market isn't bad:-) |
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Post by peppy on Jul 30, 2017 7:29:47 GMT -5
I wonder how many have the persistent cough issue with Afrezza that Cindy reportedly has. I wonder if it has something to do with the Ph of Afrezza meant to match the Ph of normal lungs? Could this persistent cough with Afrezza be caused by an acidosis, perhaps a diabetic acidosis, for example, that is caused by poorly regulated blood glucose levels? I do not believe the cough has to do with the ph. not acidosis, that I can figure out, acidosis would be in the blood and arterial blood gases would catch it. It would show in the ph of the arteriole blood gas and probably the base. edited: a respiratory acidosis would generally show a shift in Co2 on an arteriole blood gas. Afrezza dissolves in the alveoli at ph of 7.
Ever smoke brotherm? There is a learning curve to having lungs accept smoke. Same difference I think. If you want to know, light a cigarette and try it. Remember to inhale.
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Post by sportsrancho on Jul 30, 2017 7:44:07 GMT -5
I wonder how many have the persistent cough issue with Afrezza that Cindy reportedly has. I wonder if it has something to do with the Ph of Afrezza meant to match the Ph of normal lungs? Could this persistent cough with Afrezza be caused by an acidosis, perhaps a diabetic acidosis, for example, that is caused by poorly regulated blood glucose levels? I do not believe the cough has to do with the ph. not acidosis, that I can figure out, acidosis would be in the blood and arterial blood gases would catch it. It would show in the ph of the arteriole blood gas and probably the base. Afrezza dissolves in the alveoli at ph of 7.
Ever smoke brotherm? There is a learning curve to having lungs accept smoke. Same difference I think. If you want to know, light a cigarette and try it. Remember to inhale.
Right, and when some people light up and cough they never try it again. Once Afrezza gets more main stream most people won't give up in a week. ( The scratchy throat goes away )Because they will know it's good for them, and others/celebrities are using it. The kids dad said that taking a sip of something before you inhale, not just after,takes care of it until you get used to it. |
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Post by hopetoretire on Jul 30, 2017 9:24:09 GMT -5
Mods: Please delete the comment from this poster and ban him from posting here. His postings on the YMB were nothing short of ridiculous and it appears his intent here is to promote his own comment board and spread more lies and deception. Thank you. I'd vote against this recommendation. Itell is a research-maniac, but that hardly disqualifies him from a board that most of us read to keep up with the latest Mnkd developments. I think you can ignore posters you are not interested in. Easy. |
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Post by itellthefuture777 on Jul 30, 2017 11:37:27 GMT -5
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Post by sportsrancho on Jul 30, 2017 11:40:06 GMT -5
I can't get in. What does it say? |
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Post by itellthefuture777 on Jul 30, 2017 11:45:39 GMT -5
This is an update on inhaled insulin for doctors...I can see the video and answer the questions on my system. The intent if for doctors to view and learn about Afrezza...I guess it needs it's own thread if you want to create one I am okay with it. My thought was to pull data from the net and put it in one place, but am being advised by the administrator to create individual threads. I am trying to find that create thread button..once found I will re-post it or you can...my intent was for doctors to see it and watch..and I think they earn some credit..
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Post by sportsrancho on Jul 30, 2017 11:46:26 GMT -5
Drugs & Diseases
insulin inhaled (Rx)
Brand and Other Names:Afrezza
Classes: Antidiabetics, Insulins; Antidiabetics, Rapid-Acting Insulins
SECTIONS
Dosing & Uses
Adult Pediatric Geriatric
Dosage Forms & Strengths
orally inhaled powder
Available as single-use cartridges
4 units/cartridge
8 units/cartridge
12 units/cartridge
MORE...
Diabetes Mellitus (Types 1 and 2)
Orally inhaled rapid-acting insulin indicated to improve glycemic control in adults with diabetes mellitus
Dosing must be individualized
Administer via oral inhalation only at the beginning of a meal
Administer using a single inhalation per cartridge
Mealtime dose conversion
Dosage adjustment may be needed when switching from insulin to inhaled insulin
NOTE: Also see starting mealtime conversion instructions below
Up to 4 units SC = 4 units inhaled
5-8 units SC = 8 units inhaled
9-12 units SC = 12 units inhaled
13-16 units SC = 16 units inhaled
17-20 units SC = 20 units inhaled
21-24 units SC = 24 units inhaled
Starting mealtime dose
Insulin naïve: 4 units at each meal initially
Converting from SC mealtime (prandial) insulin: Determine the appropriate inhaled insulin dose for each meal by converting from the injected dose using conversion table (above)
Using SC premixed insulin: Estimate the mealtime injected dose by dividing half of the total daily injected premixed insulin dose equally among the 3 meals of the day; convert each estimated injected mealtime dose to an appropriate inhaled insulin dose (use conversion table above); administer half of the total daily injected premixed dose as an injected basal insulin dose
Dose adjustment
Adjust the inhaled insulin dosage based on the individual's metabolic needs, blood glucose monitoring results, and glycemic control goal
Dosage adjustments may be needed with changes in physical activity, changes in meal patterns (ie, macronutrient content or timing of food intake), and changes in renal or hepatic function or during acute illness
Carefully monitor blood glucose control in patients requiring high doses; if blood glucose control is not achieved with increased inhaled insulin doses, consider use of SC mealtime insulin
Dosing Considerations
Before initiating, perform a detailed medical history, physical examination, and spirometry (FEV1) in all patients to identify potential lung disease
Limitations of use
Not a substitute for long-acting insulin; must be used in combination with long-acting insulin in patients with type 1 diabetes mellitus
Not recommended for treatment of diabetic ketoacidosis
Safety and efficacy not established in patients who smoke and is not recommended in patients who smoke or who have recently stopped smoking
Administration
Keep inhaler level and white mouthpiece on top and purple base on the bottom after a cartridge has been inserted into the inhaler
Loss of drug effect can occur if the inhaler is turned upside down, held with the mouthpiece pointing down, or shaken (or dropped) after the cartridge has been inserted but before the dose has been administered
If any of the above occurs, the cartridge should be replaced before use
The inhaler can be used for up to 15 days from the date of first use; after 15 days of use, the inhaler must be discarded and replaced with a new inhaler
See complete illustrated administration instructions provided in packaging
Inhaled insulin doses >12 units
Doses >12 units require inhalations from multiple cartridges
To achieve the required total mealtime dose, patients should use a combination of 4-unit, 8-unit, and 12-unit cartridges
For doses >24 units, combinations of different multiple cartridges can be used
Storage
Before use, cartridges and inhaler should be at room temperature for 10 minutes
Cartridges not in use
Sealed [unopened] cartridges in foil package
Refrigerate at 2-8ºC (36-46ºF)
If foil package is not refrigerated, must use within 10 days
Cartridges in use
Store at room temperature (25ºC [77ºF]), excursions permitted 15-30ºC (59-86ºF)
Sealed [unopened] blister cards and strips: Must be used within 10 days
Opened strips: Must be used within 3 days
Inhaler
May be refrigerated, but should be at room temperature before use
Store between 2-25ºC (36-77ºF); excursions permitted
Next: Interactions
SECTIONS
insulin inhaled
Dosing & Uses
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Post by sportsrancho on Jul 30, 2017 11:50:24 GMT -5
This is an update on inhaled insulin for doctors...I can see the video and answer the questions on my system. The intent if for doctors to view and learn about Afrezza...I guess it needs it's own thread if you want to create one I am okay with it. My thought was to pull data from the net and put it in one place, but am being advised by the administrator to create individual threads. I am trying to find that create thread button..once found I will re-post it or you can...my intent was for doctors to see it and watch..and I think they earn some credit.. Ok, what I posted above was what I found by Googling... no video |
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Post by liane on Jul 30, 2017 12:20:42 GMT -5
itellthefuture777, Please heed my above post. Different topics should have new threads. I don't have the time or energy to move your posts around. So please put them in the right place to begin with. Thanks!
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