|
Post by kc on Aug 6, 2017 17:00:57 GMT -5
VDEX put out the tweet a few minutes ago. Good messaging by the founder of VDEX.
|
|
|
Post by dreamboatcruise on Aug 6, 2017 18:09:17 GMT -5
I think first quarterly profit was Q4 2001, and they've had positive operating cash flow ever since. I'm no Amazon historian, so correct me if I'm wrong. I didn't invest in them until a couple years ago. www.forbes.com/sites/jonmarkman/2017/05/23/the-amazon-era-no-profits-no-problem/#4b9db352437aMAY 23, 2017 @ 09:57 AM The Amazon Era: No Profits, No Problem Jon Markman , CONTRIBUTOR Analyzing tech stocks through the prism of cultural change. There is a new calculus in corporate boardrooms. Profits are so yesterday. Now it’s all about vision and great storytelling. Blame Amazon.com. The online behemoth cracked the code. Despite posting just a handful of profitable quarters in its two-decade history, it’s the fourth-largest public company at almost $470 billion in market capitalization. Now, its copycats are changing the game. Yeah, they keep reinvesting but they've consistently generated large, and growing net operating cash. It's not as if Amazon constantly has to lure in new investors to keep afloat. No one in their right mind would say Amazon has shaky finances. There is near zero chance of them heading to bankruptcy. Amazon is nothing like the dot.com bubble when companies were burning through cash reserves with nothing to show but meaningless "clicks".
|
|
|
Post by sportsrancho on Aug 6, 2017 18:41:59 GMT -5
They just got real active on Twitter. We are here to help with the fight against diabetes. We believe Afrezza first, Afrezza Instead, Afrezza Always. #vdexafrezzafirst #weneedacure
|
|
|
Post by sportsrancho on Aug 6, 2017 19:06:55 GMT -5
|
|
|
Post by sportsrancho on Aug 6, 2017 20:05:15 GMT -5
|
|
|
Post by sportsrancho on Aug 6, 2017 20:14:31 GMT -5
|
|
|
Post by sportsrancho on Aug 7, 2017 8:35:55 GMT -5
|
|
|
Post by MnkdWASmyRtrmntPlan on Aug 7, 2017 10:53:55 GMT -5
Aged - can you explain the Integrated Diabetes model a little more? What type of coaching are they providing and for what cost? I am trying to guess what type of service Onduo is planning to provide and how that may be different than what Scheiner is providing. The Cleveland Clinic has also just partnered with Oscar Insurance and I suspect diabetes will be a big focus in this partnership. We also have Roche and their MySugr deal, Medtronic/IBM and others including Dachis/One Drop. How are they all planning on making money? Seyhey, in case you didn't poke around in the link that Brotherm1 gave, the Integrated Diabetes model is explained here: integrateddiabetes.com and click on the "Our Diabetes Services" tab. Consulting services are detailed here: integrateddiabetes.com/diabetes-consulting-service/The website doesn't list the actual costs, but it does say that "Payment for all services is due when services are rendered. New (first-time) appointments must be secured by check or credit card at the time of scheduling. Retainer services go into effect at the time payment is received. Refunds are provided at the discretion of IDS." If you really want to know their cost it says: please call for current pricing on all our services: toll-free in the US 877-735-3648 Also interesting is to type Afrezza in the search and take a look at the "My Review of Afrezza Fast Acting Inhaled Insulin", which describes Gary Scheiner's experience with Afrezza. Or, you can go directly to that story here: integrateddiabetes.com/my-review-of-afrezza-fast-acting-inhaled-insulin/
|
|
|
Post by sportsrancho on Aug 7, 2017 15:51:11 GMT -5
|
|
|
Post by sportsrancho on Aug 7, 2017 19:59:36 GMT -5
Metformin ....just irresponsible !! Another great video from VDex!
|
|
|
Post by akemp3000 on Aug 7, 2017 20:11:37 GMT -5
Re Metformin and VDex: It's great there's finally a voice to speak the truth and say what many know to be true without being under the harshly restrictive parameters of the FDA. The paradigm shift to time-in-range monitoring and Afrezza has now begun and there's no turning back. We all wish it could happen faster.
|
|
|
Post by sayhey24 on Aug 7, 2017 20:15:32 GMT -5
Now that was awesome. Its about time for the "Metformin just Makes a Mess" movement to get vocal and for the Step program to change in 2018. As Dr. Ralph DeFronzo from the University of Texas Health Science Center said at the ADA BeyondA1c forum said last month “The most waste in type 2 diabetes is to continuously put people on metformin and sulfonylureas (glyburide, glimepiride, etc.). These drugs have no protective effect on the beta cell, and by the time you figure out what you’re doing, there are no beta cells left to save.” diatribe.org/the-diatribe-foundation-and-tcoyd-11th-annual-forum
|
|
|
Post by agedhippie on Aug 7, 2017 21:20:14 GMT -5
Metformin ....just irresponsible !! Another great video from VDex! That's the problem when you have someone who is runs hair restoration talking about endocrinology. The failure of beta cells is progressive and irreversible because of genetics. Yes running high levels will kill them faster from stress but relieving the stress does not fix the underlying genetics. Insulin is not a magic bullet, and you will need progressively more insulin as time goes on. In the same way as time goes on you need progressively more metformin. The difference is that at a certain point you can take no more metformin, that is never true of insulin. There are other options out there that are not insulin. Sayhey likes to quote Dr. Ralph DeFronzo but not his entire position. DeFronzo's position is that taking metformin or any other monotherapy doesn't not make sense - you should take drug cocktails for the best effect. Personally I am not keen on a lot of those drugs but you can certainly get good results of them. Ultimately, although the good hair restorer doesn't mention it, you have to accept responsibility for your treatment. If you take metformin and never bother to check then in time your dose is going to be inadequate and you will have problems. Equally if you are on Afrezza and don't bother to check then over time you dose will also become inadequate and you will have problems on Afrezza too. Afrezza is not a cure, it's just insulin, and as your insulin resistance gets worse you will need more - that the genetics.
|
|
|
Post by thall on Aug 7, 2017 21:20:15 GMT -5
Now that was awesome. Its about time for the "Metformin just Makes a Mess" movement to get vocal and for the Step program to change in 2018. As Dr. Ralph DeFronzo from the University of Texas Health Science Center said at the ADA BeyondA1c forum said last month “The most waste in type 2 diabetes is to continuously put people on metformin and sulfonylureas (glyburide, glimepiride, etc.). These drugs have no protective effect on the beta cell, and by the time you figure out what you’re doing, there are no beta cells left to save.” diatribe.org/the-diatribe-foundation-and-tcoyd-11th-annual-forumThey may have been quoting Dr. DeFronzo out of context. He was responsible for getting metformin approved in the first place: www.diabetesincontrol.com/dr-ralph-defronzo-part-1-introduction-and-ada-2017/
"I actually was the person who was responsible, to get Metformin approved by the FDA. That happened in 1995. We thought, “man, we’re in heaven now, we have two drugs. We have Metformin and sulfonylureas.” Then you think about all the drugs that we have now, how much better off patients’ lives are and how much easier it is for doctors to get people under control. The big problem now as I see it is affordability of many of the newer medications, which work really quite well compared to the older medications but are also quite expensive."
|
|
|
Post by mnholdem on Aug 7, 2017 21:37:54 GMT -5
Aged, the majority of patients that lose complete beta cell function is not because of genetics. Some HCP continue to perpetuate this fallacy by lumping all Type 1s together. Genetics is certainly indicated in children who lose beta cells, but they are a relatively small segment of the diabetes population as a whole.
|
|