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Post by itellthefuture777 on Aug 30, 2017 12:53:36 GMT -5
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Post by itellthefuture777 on Aug 30, 2017 12:53:58 GMT -5
Reducing the Risk of Preventable Adverse Drug Events associated with Hypoglycemia in the Older Population
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Post by itellthefuture777 on Aug 30, 2017 12:54:48 GMT -5
The purpose of this workshop is to discuss the importance of individualized glycemic control targets for older patients with diabetes, in order to reduce the risk of serious hypoglycemia, identify and discuss medication safety efforts, both those that are part of the Safe Use Initiative and those external to FDA, that are of direct relevance and importance to older patients living with the disease, discuss future areas of research which could be explored to reduce the risk of serious hypoglycemia in older diabetic patients, and disseminate the results of this discussion to inform patients, patient advocates, and healthcare practitioners.
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Post by dreamboatcruise on Aug 30, 2017 16:55:20 GMT -5
Unfortunately "individualized glycemic control targets for older patients" has in the past meant accepting A1c levels that are too high and causing damage in order to avoid hypoglycemia, with the reasoning damage to the body doesn't matter as much if someone is old and unlikely to live as long. Hopefully that notion will be questioned at this workshop. Wonder if MNKD will be there.
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Post by sayhey24 on Aug 31, 2017 7:06:44 GMT -5
DBC - its a good thing times are changing. The diabetic never had a tool like afrezza in the past which mimicked natural pancreatic insulin. Thanks to Al Mann now they do. Thanks to his accountant they now have Dexcom's real time CGM which allows automated cloud tracking/profiling and data point storage.
Its appearing the technology has finally caught up to allow the rest of the world to understand what Al was saying 20 years ago. Its seeming afrezza's time has come.
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Post by peppy on Aug 31, 2017 8:11:38 GMT -5
Unfortunately "individualized glycemic control targets for older patients" has in the past meant accepting A1c levels that are too high and causing damage in order to avoid hypoglycemia, with the reasoning damage to the body doesn't matter as much if someone is old and unlikely to live as long. Hopefully that notion will be questioned at this workshop. Wonder if MNKD will be there. A1C GOALS
For glycemic goals in children, please refer to Section 12 “Children and Adolescents.” For glycemic goals in pregnant women, please refer to Section 13 “Management of Diabetes in Pregnancy.”
Recommendations
•A reasonable A1C goal for many nonpregnant adults is <7% (53 mmol/mol). A
•Providers might reasonably suggest more stringent A1C goals (such as <6.5% [48 mmol/mol]) for selected individual patients if this can be achieved without significant hypoglycemia or other adverse effects of treatment (i.e., polypharmacy). Appropriate patients might include those with short duration of diabetes, type 2 diabetes treated with lifestyle or metformin only, long life expectancy, or no significant cardiovascular disease. C
•Less stringent A1C goals (such as <8% [64 mmol/mol]) may be appropriate for patients with a history of severe hypoglycemia, limited life expectancy, advanced microvascular or macrovascular complications, extensive comorbid conditions, or long-standing diabetes in whom the goal is difficult to achieve despite diabetes self-management education, appropriate glucose monitoring, and effective doses of multiple glucose-lowering agents including insulin. B
care.diabetesjournals.org/content/40/Supplement_1/S48
Hba1c of 8 = 183mg/dl 7 = 153mg/dl 
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------- HbA1c goals are changed if the person can not meet a lower goal. plenty of lip service.
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