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Post by agedhippie on Jan 30, 2019 11:42:08 GMT -5
Afrezza usage is different from other RAA - for instance, a few mins into a meal, one or more follow-up dosages, unit conversion. Afrezza needs to be optimally used according to ATA (Different titration) to showcase TIR, TTT which are measurable outcomes to improve insurance coverage. In a nutshell, Superiority study needs to also incorporate usage. It’s pretty common that different meds have different usages as normally shown on the labels. The out of control T2 successful Study may potentially reduce some Step Therapy, PA requirements. I agree entirely. Afrezza works differently from RAA and needs to be dosed accordingly. There is no issue with that in a trial, as you say it happens all the time. The STAT protocol should be used and the STAT pilot answers any possible safety objections to the protocol. I would go further and trial Afrezza against FIASP. The FDA doesn't like comparisons between drugs, but if FIASP is the control arm then there cannot be any objection. |
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Post by boca1girl on Jan 30, 2019 13:41:23 GMT -5
New dispensers make insulin more expensive. We’re seeing that again with Afrezza, a relatively new rapid-acting insulin, and the first and only insulin to be delivered as an inhalable powder. One unit of Afrezza’s insulin can cost as much as three times other rapid-acting insulins. Cash Prices of Rapid-Acting Insulins (July 2018) Price per dispenser Price per insulin unit Insulin lispro Admelog vial (10 ml) $303 per vial $0.30 per unit Humalog vial (10 ml) $340 per vial $0.34 per unit Admelog Solostar pen (3 ml) $117 per pen $0.39 per unit Humalog Kwikpen (3 ml) $135 per pen $0.45 per unit Insulin aspart Novolog vial (10 ml) $341 per vial $0.34 per unit Novolog Flexpen (3 ml) $130 per pen $0.44 per unit Insulin glulisine Apidra vial (10 ml) $349 per vial $0.35 per unit Apidra Solostar pen (3 ml) $136 per pen $0.45 per unit Inhaled insulin Afrezza cartridge (4 units) $3.60 per cartridge $0.90 per unit *Insulins concentrations are 100 units/ml unless otherwise stated. |
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sky
Lab Rat
Posts: 46 
Sentiment: Long
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Post by sky on Jan 30, 2019 15:02:01 GMT -5
You get what you pay for.
Insurance companies don't think like that.
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Post by pantaloons on Feb 11, 2019 22:43:57 GMT -5
Here's an idea that I have not seen discussed much on this board: concierge medicine. Generally, clients of concierge physicians are wealthy and are more than apt to afford premium medications either with or without insurance. How strategic would it be to have a handful of sales reps connect with concierge physicians? Although they may make up only a minority of the potential market, I imagine this would be a "high yield" patient population (i.e., no financial barriers). Perhaps MNKD is or already has explored this route.
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Post by mnkdfann on Feb 11, 2019 23:26:12 GMT -5
Here's an idea that I have not seen discussed much on this board: concierge medicine. Generally, clients of concierge physicians are wealthy and are more than apt to afford premium medications either with or without insurance. How strategic would it be to have a handful of sales reps connect with concierge physicians? Although they may make up only a minority of the potential market, I imagine this would be a "high yield" patient population (i.e., no financial barriers). Perhaps MNKD is or already has explored this route. I suggested something along those lines a few weeks back: mnkd.proboards.com/post/169248Some others probably also mentioned the same sort of idea from time to time in the past. It's hard to believe Mannkind never thought of this. So perhaps it either simply has not worked, or they decided it wasn't the way to go. |
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Post by Thundersnow on Feb 12, 2019 0:49:26 GMT -5
Here's an idea that I have not seen discussed much on this board: concierge medicine. Generally, clients of concierge physicians are wealthy and are more than apt to afford premium medications either with or without insurance. How strategic would it be to have a handful of sales reps connect with concierge physicians? Although they may make up only a minority of the potential market, I imagine this would be a "high yield" patient population (i.e., no financial barriers). Perhaps MNKD is or already has explored this route. I suggested something along those lines a few weeks back: mnkd.proboards.com/post/169248Some others probably also mentioned the same sort of idea from time to time in the past. It's hard to believe Mannkind never thought of this. So perhaps it either simply has not worked, or they decided it wasn't the way to go. That was initiated when the ACA started. Drs. realized they will not be making $2 Million a year and only $1 Million so they started a VIP Service. You pay an annual or monthly retainer and have 24 hour access to your doctor. |
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Post by mnkdfann on Feb 12, 2019 8:40:35 GMT -5
I suggested something along those lines a few weeks back: mnkd.proboards.com/post/169248Some others probably also mentioned the same sort of idea from time to time in the past. It's hard to believe Mannkind never thought of this. So perhaps it either simply has not worked, or they decided it wasn't the way to go. Drs. realized they will not be making $2 Million a year and only $1 Million so they started a VIP Service. You pay an annual or monthly retainer and have 24 hour access to your doctor. Concierge medicine existed long before the ACA. www.seattlemag.com/article/why-concierge-care-becoming-more-popular-seattleConcierge medicine has its roots in Seattle, beginning in the mid-1990s when former Seattle SuperSonics physician Dr. Howard Maron and Dr. Scott Hall founded concierge clinic MD2. A few years later, Virginia Mason Medical Center began developing its program, one of the country’s first concierge practices housed within a multidisciplinary academic hospital. Since then, it’s estimated that some 12,000 doctors nationwide have adopted a concierge model.
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