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Post by itellthefuture777 on Jan 9, 2019 0:14:21 GMT -5
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Post by mango on Jan 9, 2019 1:10:57 GMT -5
I threw up in my mouth a little watching that. 🤒 Did Sanofi pay for this person to speak? I wanted to reach through the screen and slap a bastid. |
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Post by itellthefuture777 on Jan 9, 2019 1:17:26 GMT -5
I threw up in my mouth a little watching that. 🤒 Did Sanofi pay for this person to speak? I watched pt 1,2,3..in I think from Part 1 it was obvoius she was pushing FIASP (not for price) and other insulins based on price not patient outcomes or time in range or quickness of pkp..just a bunch of mumbojumbo..I couldn't believe what I was watching! There should be a secondary educator in these rooms to monitor what is being taught for tomorrows precriptioners...really the worst I have ever seen. That said ..and unrelated..check this out www.google.com/amp/s/cannabisnow.com/jp-morgan-jumps-onto-marijuana-stock-bandwagon-with-gw-pharmaceuticals/amp/ |
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Post by liane on Jan 9, 2019 6:39:43 GMT -5
I don't want this to sound like I'm defending this lecturer, but I want people to understand this is what we're currently up against at present in the medical schools. There is an enormous volume of information that must be conveyed to students in a manner that they can pass their board exams. At this point in time, it's not about patient care, it's about learning material in a way that improves board scores.
It's clear that this educator does not have much real time experience with Afrezza and has not taken the time to change her standard practice and improve her patients' experiences. But what she is doing here is conveying the "party-line" information on insulin prescribing so that the students will regurgitate that on exams. Secondarily, they will not sound totally clueless on 1st day of clinical rotations when their attending physicians start pimping them on the basics of starting a patient on insulin.
Absolutely, this needs to change. But it will need more Afrezza experience percolating into physician practice. And it will take changing the SOC (and this has been argued to death on this board - we need the studies to prove AFAL).
I often kid that even I could manage a diabetic patient on Afrezza (I know I could). I've been following MNKD for almost 10 years. I'm in a specialty far removed from endocrinology or even primary care. So unfortunately, about the most I can do is occasionally recommend a patient ask their PCP about Afrezza - and we know how far that will go. I can't even get any traction with physician colleagues - they know my credentials and scoff - what would I know about diabetes care. Also, the ghost of Exubera is still alive and well in this area. Maybe I need to open a Vdex side gig...
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Post by prcgorman2 on Jan 9, 2019 7:07:43 GMT -5
This may help to explain why Dr. Castagna is so passionate about TV DTC advertising as a method to at least make the 225,000 PCPs in the US aware of an alternative.
If any of you are in correspondence with Mike, can you answer why they've chosen the flying hamburger commercial? It's nice that it won an award, but I have to wonder what were the criteria and who were the judges? They might know about making commercials, but I suspect they don't know spit about diabetes and insulin.
I think if MNKD wants to sell to doctors (the prescribers after all) and diabetics (the advocates after all), the commercial just has to quickly easily demonstrate the value proposition of Afrezza which above all else is the ultra-rapid onset of effective action (ever inhale from a cigarette or albuterol inhaler?) and the rapid elimination from the body. And, since this is a mealtime insulin, the context of the commercial has to be a meal (at least the silly-ass flying hamburgers got that part right).
How hard is this? Have two diabetics sit down for a meal. They order. Maybe have a carb-light order from one, and a carb-heavy order from the other. Again, has to be dead simple. Italian restaurant, chicken carbonara with asparagus versus spaghetti and meatballs. Chicken carbonara orders, gets up, goes to the bathroom, clicks his/her pen, injects into the abdomen (I would use a woman because injections hurt in the mind of most of the audience many of whom are future Type 2s and we're more sympathetic to women is my sexist view). Chicken carbonara returns, the meal arrives, and spaghetti and meatball loads the dreamboat and inhales. Hopefully it whistles a little, and they explain to chicken carbonara and perhaps a third non-PWD guest/friend, "It's OK, I'm just taking my Afrezza mealtime insulin.". Cut to the voice over caveats.
Now, all the while these scenes are going, I would split screen the separation between chicken carbonara PWD and spaghetti PWD with a CGM-like display underneath showing blood glucose levels over time. I would want real PWDs and real BG readings. The voice-over needs to conclude results may vary and whatever other caveats are acceptable by the FDA.
I would enlist the support of whoever it is at the FDA that reviews TV commercials to create the story board. The FDA has to allow commercials, and they provide guidelines and reviews, so better to work with them pre-production (and maybe this was done for the flying hamburger commercial).
Anyway, the commercial should show real PWDs with real BGs over time with the difference in adminstration routes and the difference in BG experience over time. Period.
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Post by mango on Jan 9, 2019 10:45:08 GMT -5
This may help to explain why Dr. Castagna is so passionate about TV DTC advertising as a method to at least make the 225,000 PCPs in the US aware of an alternative. If any of you are in correspondence with Mike, can you answer why they've chosen the flying hamburger commercial? It's nice that it won an award, but I have to wonder what were the criteria and who were the judges? They might know about making commercials, but I suspect they don't know spit about diabetes and insulin. I think if MNKD wants to sell to doctors (the prescribers after all) and diabetics (the advocates after all), the commercial just has to quickly easily demonstrate the value proposition of Afrezza which above all else is the ultra-rapid onset of effective action (ever inhale from a cigarette or albuterol inhaler?) and the rapid elimination from the body. And, since this is a mealtime insulin, the context of the commercial has to be a meal (at least the silly-ass flying hamburgers got that part right). How hard is this? Have two diabetics sit down for a meal. They order. Maybe have a carb-light order from one, and a carb-heavy order from the other. Again, has to be dead simple. Italian restaurant, chicken carbonara with asparagus versus spaghetti and meatballs. Chicken carbonara orders, gets up, goes to the bathroom, clicks his/her pen, injects into the abdomen (I would use a woman because injections hurt in the mind of most of the audience many of whom are future Type 2s and we're more sympathetic to women is my sexist view). Chicken carbonara returns, the meal arrives, and spaghetti and meatball loads the dreamboat and inhales. Hopefully it whistles a little, and they explain to chicken carbonara and perhaps a third non-PWD guest/friend, "It's OK, I'm just taking my Afrezza mealtime insulin.". Cut to the voice over caveats. Now, all the while these scenes are going, I would split screen the separation between chicken carbonara PWD and spaghetti PWD with a CGM-like display underneath showing blood glucose levels over time. I would want real PWDs and real BG readings. The voice-over needs to conclude results may vary and whatever other caveats are acceptable by the FDA. I would enlist the support of whoever it is at the FDA that reviews TV commercials to create the story board. The FDA has to allow commercials, and they provide guidelines and reviews, so better to work with them pre-production (and maybe this was done for the flying hamburger commercial). Anyway, the commercial should show real PWDs with real BGs over time with the difference in adminstration routes and the difference in BG experience over time. Period. That's a brilliant idea for a commercial. I love it. |
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Post by sportsrancho on Jan 9, 2019 12:02:36 GMT -5
This has always been the best idea for a commercial. I want our money spent on this. Get Sam, Eric, Laura to do it. Couldn’t have any more appealing people. How much could that possibly cost? I’m not familiar.
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Post by nylefty on Jan 9, 2019 12:18:25 GMT -5
Now, all the while these scenes are going, I would split screen the separation between chicken carbonara PWD and spaghetti PWD with a CGM-like display underneath showing blood glucose levels over time. I would want real PWDs and real BG readings. The voice-over needs to conclude results may vary and whatever other Anyway, the commercial should show real PWDs with real BGs over time with the difference in adminstration routes and the difference in BG experience over time. Period. The FDA would never allow this. Anecdotal evidence is not allowed in prescription drug advertising, period. |
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Post by mango on Jan 9, 2019 12:43:26 GMT -5
This has always been the best idea for a commercial. I want our money spent on this. Get Sam, Eric, Laura to do it. Couldn’t have any more appealing people. How much could that possibly cost? I’m not familiar. x2 |
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Post by itellthefuture777 on Jan 9, 2019 14:51:33 GMT -5
If there was a commercial...it should show a side by side where Afrezza is taken..then immetiately eating while showing the pkp..as the Afrezza user is eating the other is waiting..to eat..then eats..but by then the Afrezza user is shopping...or do a part 1 part 2 part 3 time skipping to show..the slower FIASP insulin..against Afrezza..(might as well take them out first)
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Post by mannmade on Jan 9, 2019 14:55:29 GMT -5
Actually as complex as Afrezza is to explain if testimonials were allowed (as I have recommended for several years now) but know they are not permitted by fda. I would create an infomercial and show people eating in real time with Dexcom monitors on display w a doc and real patients. Explain afrezza inbetween.
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Post by boca1girl on Jan 9, 2019 18:51:33 GMT -5
I know we’ve rehashed these testimonials not being allowed before but I can’t understand how Cyndii Lauper does it for the scorisis drug and Ray Liotta does it for Chantix, the stop smoking drug.
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Post by awesomo on Jan 9, 2019 19:11:49 GMT -5
I know we’ve rehashed these testimonials not being allowed before but I can’t understand how Cyndii Lauper does it for the scorisis drug and Ray Liotta does it for Chantix, the stop smoking drug. I'm sure they get FDA approval beforehand for the content in the commercial. Plus, it's not really actually testimonials, just actors reading a script. |
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Post by boca1girl on Jan 9, 2019 19:24:24 GMT -5
I know we’ve rehashed these testimonials not being allowed before but I can’t understand how Cyndii Lauper does it for the scorisis drug and Ray Liotta does it for Chantix, the stop smoking drug. I'm sure they get FDA approval beforehand for the content in the commercial. Plus, it's not really actually testimonials, just actors reading a script. I don’t agree that they are just actors in these two cases. |
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Post by prcgorman2 on Jan 9, 2019 22:25:11 GMT -5
Correct. They're definitely saying they have used these drugs for their needs and they identify them as the celebrities they are. These are testimonials.
I have to agree that a commercial for insulin should receive more scrutiny than a drug for quitting smoking or skin afflictions. Regardless, the FDA acknowledged the fast onset of effective action and permitted a label change, so it can't with a straight face say it is inappropriate to highlight this key part of the drug's value in advertisements. And, as I said, maybe Mannkind did collaborate with the FDA on preproduction of the flying hamburger commercial I think is so lackluster. Just don't know. I know what I think would be more effective as an advertisement, but don't know how much of it is acheivable.
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