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Post by peppy on Feb 27, 2020 5:56:33 GMT -5
So sorry to hear that, everybody’s been wondering what he’s been doing..that must’ve been crushing. What about United is questionable? And did Pat quit because of lack of sales? What is it about the physicians/clinics that makes the Top 10 Afrezza writers so successful? MannKind's Chief Medical Officer SHOULD be paying attention to these endocrinologists. They may possess some of the answers needed to win greater adoption for Afrezza. Frankly, if he isn't already, Dr. Kendall should also make the time to "hob nob" with Vdex doctors. Frankly, pguererro's commentary about what Dr Kendall's activities consist of is simply not credible, although I would like to see a larger, more visible role for the CMO.  Reminds me when Sanofi met with a group of successful early adopters before dropping the MNKD contract. The rumor was Sanofi wanted to know their dosing habits. I think Kendall should have meeting with health insurer representatives, everyday. How many health insurance companies are there? 7? just a guess. Then he should meet with Lilly. |
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CCO Gone
Feb 27, 2020 6:58:23 GMT -5
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Post by bioexec25 on Feb 27, 2020 6:58:23 GMT -5
Mn, I agree CMO and CCO need to broaden their roles and better align their plans (within Regulatory constraints). I believe Pharma is doing a lot to plan and manage the consolidation and vertical integration going on in the industry. All of the change in this space is bringing both opportunities and threats. www.drugchannels.net/2019/12/insurers-pbms-specialty-pharmacies.html?m=1 |
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CCO Gone
Feb 27, 2020 6:59:53 GMT -5
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Post by pat on Feb 27, 2020 6:59:53 GMT -5
There are so many naive comments on this site regarding real world choices for today’s doctor and treating diabetes I stopped righting down notes on who to respond to and how. I started this by telling u a fact. U guys haven’t talked to multiple patients and multiple prescribers about Afrezza. Hell double down on your investment. Mike will spin a new thread at the next big conference. Also, VDEX Is a losing proposition as well (sorry Sports). It’s Afrezza The sky is falling! Look at me. The sucker who keeps buying. |
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Post by sayhey24 on Feb 27, 2020 7:04:57 GMT -5
Sports I think you are a great add to VDEX but your response of “things are yet to come” sounds like the same old Afrezza stuff. Maybe they had 6 locations in 2018 and now they have 5. The white paper never moved the needle and also didn’t spur expansion. PG - I have taken the time to read all you posts on this thread. I am trying to understand what you think the answer is? You say the VDex white paper did not move the needle. Why do you think that is? I discussed this white paper with a member of the MRK M&A team. She laughed at it. She said it was the typical type of paper put out to pump a stock. Of course this was before Dr. Kendall came on board and before ADA2019 and the recent presentations. As I have said to her about the VDex paper, just try it yourself. BTW - she is no longer laughing. The problem with afrezza is two fold; the first is afrezza was marketed as insulin and everyone knows what insulin is, its dangerous. Its the last thing you want to prescribe to a T2. Insulin is that damn dangerous and PCPs have been trained and conditioned to give their PWD pills. Follow the SoC designed to fail, do the next step until everything fails and then give them the insulin. The second issue afrezza has is the Big One. Its the one I discussed with Mike when I first met him and told him afrezza was doomed if it was not for the CGM. This was 4 years ago and Mike didn't even understand CGMs at the time. The issue is $$$. If the diabetes community got behind afrezza as Al Mann expected them to it would totally disrupt the entire diabetes community. Thousands of people would be out of jobs and $Bs in sale in BP would disappear. Could you imagine what would happen if afrezza was used as Step 1 for T2 treatment and do what VDex is saying? There would be no Step 2,3, or 4. Significant reductions in amputations and heart disease would be realized. However hitting home, the funding for the ADA would dry-up, along with all the research for new drugs. Why does the ADA want to change the SoC to have this happen? As I told Mike 4 years ago, the CGM will save afrezza. WIthout it afrezza was doomed. The community can not hide behind the numbers but we are still at the beginning. Unless I buy my libre on EBay I have to get a script to go to Walmart and get one. That will change. I have hoped Tim Cook does something sooner than later but nothing yet. I had hoped and expected the India study would include the Libre but it got shut down because it was not approved in India. Mike thinks he has a 2021 plan for the T2s with connected care. I hope he does. However in the mean time I think he should have gotten behind the clinic approach like the VDexs and opened a crack in the wall for afrezza sales from the bottom up. Why his sale force has not forced this approach is a head-scratcher to me. |
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Post by peppy on Feb 27, 2020 7:41:07 GMT -5
Sports I think you are a great add to VDEX but your response of “things are yet to come” sounds like the same old Afrezza stuff. Maybe they had 6 locations in 2018 and now they have 5. The white paper never moved the needle and also didn’t spur expansion. PG - I have taken the time to read all you posts on this thread. I am trying to understand what you think the answer is? You say the VDex white paper did not move the needle. Why do you think that is? I discussed this white paper with a member of the MRK M&A team. She laughed at it. She said it was the typical type of paper put out to pump a stock. Of course this was before Dr. Kendall came on board and before ADA2019 and the recent presentations. As I have said to her about the VDex paper, just try it yourself. BTW - she is no longer laughing. The problem with afrezza is two fold; the first is afrezza was marketed as insulin and everyone knows what insulin is, its dangerous. Its the last thing you want to prescribe to a T2. Insulin is that damn dangerous and PCPs have been trained and conditioned to give their PWD pills. Follow the SoC designed to fail, do the next step until everything fails and then give them the insulin. The second issue afrezza has is the Big One. Its the one I discussed with Mike when I first met him and told him afrezza was doomed if it was not for the CGM. This was 4 years ago and Mike didn't even understand CGMs at the time. The issue is $$$. If the diabetes community got behind afrezza as Al Mann expected them to it would totally disrupt the entire diabetes community. Thousands of people would be out of jobs and $Bs in sale in BP would disappear. Could you imagine what would happen if afrezza was used as Step 1 for T2 treatment and do what VDex is saying? There would be no Step 2,3, or 4. Significant reductions in amputations and heart disease would be realized. However hitting home, the funding for the ADA would dry-up, along with all the research for new drugs. Why does the ADA want to change the SoC to have this happen? As I told Mike 4 years ago, the CGM will save afrezza. WIthout it afrezza was doomed. The community can not hide behind the numbers but we are still at the beginning. Unless I buy my libre on EBay I have to get a script to go to Walmart and get one. That will change. I have hoped Tim Cook does something sooner than later but nothing yet. I had hoped and expected the India study would include the Libre but it got shut down because it was not approved in India. Mike thinks he has a 2021 plan for the T2s with connected care. I hope he does. However in the mean time I think he should have gotten behind the clinic approach like the VDexs and opened a crack in the wall for afrezza sales from the bottom up. Why his sale force has not forced this approach is a head-scratcher to me. "afrezza was doomed if it was not for the CGM." The blind can now see. The blind Endo's can now see. What are they doing about it? They have been trained to stay with in the standards of care and only prescribe what the insurer covers. I am a zoo monkey throwing poop. |
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CCO Gone
Feb 27, 2020 8:33:18 GMT -5
via mobile
Post by mango on Feb 27, 2020 8:33:18 GMT -5
So sorry to hear that, everybody’s been wondering what he’s been doing..that must’ve been crushing. What about United is questionable? And did Pat quit because of lack of sales? What is it about the physicians/clinics that makes the Top 10 Afrezza writers so successful? MannKind's Chief Medical Officer SHOULD be paying attention to these endocrinologists. They may possess some of the answers needed to win greater adoption for Afrezza. Frankly, if he isn't already, Dr. Kendall should also make the time to "hob nob" with Vdex doctors. Frankly, pguererro's commentary about what Dr Kendall's activities consist of is simply not credible, although I would like to see a larger, more visible role for the CMO. I may have misheard MC on the CC, but I swear I thought he mentioned they were in the process of hiring a Pediatric Endocrinologist. Anyone catch that? |
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Post by cjm18 on Feb 27, 2020 9:02:53 GMT -5
So Afrezza is bad. Afrezza is the problem Bc the patient has to inhale 8 times a day. Anything else pg?
Do vdex patients inhale 8 times a day?
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Post by sportsrancho on Feb 27, 2020 9:11:46 GMT -5
What is it about the physicians/clinics that makes the Top 10 Afrezza writers so successful? MannKind's Chief Medical Officer SHOULD be paying attention to these endocrinologists. They may possess some of the answers needed to win greater adoption for Afrezza. Frankly, if he isn't already, Dr. Kendall should also make the time to "hob nob" with Vdex doctors. Frankly, pguererro's commentary about what Dr Kendall's activities consist of is simply not credible, although I would like to see a larger, more visible role for the CMO. I mam have misheard MC on the CC, but I swear I thought he mentioned they were in the process of hiring a Pediatric Endocrinologist. Anyone catch that? I did not hear it. And I think what pq said about Mannkind and most of the scripts coming from 10 providers and the fact that Kendall spends most of his time with them is very credible. And yes.... what are they doing right? This is what I get from this ...maybe I’m off-base, but this is what it sounds like to me. ( In pq’s opinion ) It’s not management. It’s not the sales reps Vdex isn’t moving fast enough The dog don’t hunt! So let’s put it in a different environment....From golfeveryday Everyone needs to face facts that Afrezza needs a hands on patient education model as the main strategy until enough patients are on it successfully and enough docs have seen the potential to take the time to even want to prescribe it. They should be calling on diabetes education centers almost exclusively. They should only be hiring diabetes educators as reps who could be conducting inhalable insulin information sessions in pharmacies and hand hold patients who want to switch to Afrezza. They don’t have to partner with Vdex but they should publicly acknowledge the good work they are doing and offer them at least a deal on samples to continue to do that work. Giving Vdex samples would be way more effective than giving it to docs right now. Vdex knows how to use those samples. Docs don’t. |
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Post by sportsrancho on Feb 27, 2020 9:20:23 GMT -5
So Afrezza is bad. Afrezza is the problem Bc the patient has to inhale 8 times a day. Anything else pg? Do vdex patients inhale 8 times a day? Vdex is after non-diabetic numbers and the least amount of inhalations possible ...it takes a few weeks-months for that to be accomplished. But then insurance is on board and the patient is on board for life. |
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Post by mango on Feb 27, 2020 9:23:10 GMT -5
I'll go back and listen later today, I'm 99% sure he said that.
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Post by peppy on Feb 27, 2020 9:24:51 GMT -5
So Afrezza is bad. Afrezza is the problem Bc the patient has to inhale 8 times a day. Anything else pg? Do vdex patients inhale 8 times a day? If my pancreas stops working I have to inhale 8 times a day? If the heart stopped working, would have to compress 70 times a min, 4,200 compressions an hour, and 100,800 compressions a day. Good thing the heart didn't stop. Can you imagine being a physician or nurse having to work a code? What a bother the patient is making me compress........ Or just get the automated external defibrillator. I have had it with stupid. pguererro |
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Post by peppy on Feb 27, 2020 9:26:36 GMT -5
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Post by mango on Feb 27, 2020 9:30:26 GMT -5
Even 8 inhalations a day is not a treatment burden, IMO. It is a painless, very quick process from start to finish loading a cartridge and inhaling the insulin. If the excuse is "I don't have time to inhale 8 times a day," then I argue well you have to MAKE TIME. You make time to go shopping, you make time to have yard of the month, you make time to get on social media, you make time to watch TV, you make time to wash your car, you make time to clean your car, and on and on...you have to MAKE TIME for you health! You can't ever expect to live as a non-diabetic or close to non-diabetic if you are not willing to make time for your health. If you refuse to make time to inhale a couple of times per meal then you obviously have other issues.
All in my opinion of course. You gotta make time, you're always going to be leaving your car, you're always going to be leaving your house, you're always going to be leaving your yard...you'll never be leaving your body while you are alive so make time!
But, that's just mango'stakeonit
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Post by boca1girl on Feb 27, 2020 9:32:19 GMT -5
I'll go back and listen later today, I'm 99% sure he said that. He did say he has a point person for Peds trials/strategy but I don’t remember him using the title Endocrinologist. It was in the Q&A section I believe. If I can find it, I’ll post it. From the Q&A section: So we think that's the big opportunity to start to layout that foundation and we'll confirm that through our market assessments that we're doing or conduct as we speak. Looking to higher dedicated marketer to lead that up as well as pre academic knowledge, so we're really going to start to focus our efforts to make sure we do a great job in the pediatric segment. And we think it's a big opportunity, but we'll confirm that through additional research. |
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Post by mango on Feb 27, 2020 9:33:53 GMT -5
Hmm can't find it. In my own defense I am deaf in one ear so, yeah obviously misheard him ☹️ |
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