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Post by centralcoastinvestor on Mar 4, 2020 12:25:18 GMT -5
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Post by rfogel on Mar 4, 2020 16:52:53 GMT -5
I think the problem remains of demonstrating that TIR is a better predictor of clinical outcome than A1c. While it might appear to make sense, insurers likely flinch at the cost of providing CGMs to all the patients.
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Post by mnkdfann on Mar 4, 2020 17:18:02 GMT -5
Interesting that other pharmas are members of the Coalition, yet Mannkind is not. |
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Post by sayhey24 on Mar 4, 2020 18:47:09 GMT -5
I think the problem remains of demonstrating that TIR is a better predictor of clinical outcome than A1c. While it might appear to make sense, insurers likely flinch at the cost of providing CGMs to all the patients. What are you trying to demonstrate? There are a bunch of studies dating back many years showing PPG over 140 for 2 hours leads to vascular damage. Would you like to reduce heart disease the #1 killer in the USA? Get the PPG down asap. The goal of all T2s should be getting them back to baseline within 2 hours - aka TIR. How is that working out for our metformin, SGLT2 and GLP1 users? Here is one from more than a decade ago www.ncbi.nlm.nih.gov/pmc/articles/PMC2688503/ |
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Post by sayhey24 on Mar 4, 2020 18:53:55 GMT -5
Open letter to Mike -
Mike whats wrong with this picture? "Consisting of accomplished researchers, people living with diabetes, and leaders from the American Diabetes Association, Abbott Diabetes Care, AstraZeneca, Dexcom, Insulet, Lilly Diabetes, and Novo Nordisk, the Coalition seeks to help establish time in range as a common and essential metric of diabetes care and management."
Mike, did they forget to mention MNKD? Come on man!!! Why is Dr. Kendall not leading this coalition? Both Kevin Sayer and Abbott are there. Nothing but nothing can achieve TIR better than afrezza. Heck, his old buddies from Lilly are there. Can we get MNKD involved in this? You need to get the SoC changed asap.
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Post by sportsrancho on Mar 4, 2020 20:07:02 GMT -5
Open letter to Mike - Mike whats wrong with this picture? "Consisting of accomplished researchers, people living with diabetes, and leaders from the American Diabetes Association, Abbott Diabetes Care, AstraZeneca, Dexcom, Insulet, Lilly Diabetes, and Novo Nordisk, the Coalition seeks to help establish time in range as a common and essential metric of diabetes care and management." Mike, did they forget to mention MNKD? Come on man!!! Why is Dr. Kendall not leading this coalition? Both Kevin Sayer and Abbott are there. Nothing but nothing can achieve TIR better than afrezza. Heck, his old buddies from Lilly are there. Can we get MNKD involved in this? You need to get the SoC changed asap. |
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Post by ktim on Mar 4, 2020 20:44:07 GMT -5
Open letter to Mike - Mike whats wrong with this picture? "Consisting of accomplished researchers, people living with diabetes, and leaders from the American Diabetes Association, Abbott Diabetes Care, AstraZeneca, Dexcom, Insulet, Lilly Diabetes, and Novo Nordisk, the Coalition seeks to help establish time in range as a common and essential metric of diabetes care and management." Mike, did they forget to mention MNKD? Come on man!!! Why is Dr. Kendall not leading this coalition? Both Kevin Sayer and Abbott are there. Nothing but nothing can achieve TIR better than afrezza. Heck, his old buddies from Lilly are there. Can we get MNKD involved in this? You need to get the SoC changed asap. Leading a coalition would be time consuming. That would be incompatible with Dr. K's goal of having this be the easiest job he's ever had    |
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