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Post by Clement on Dec 18, 2022 13:33:01 GMT -5
A patient might need a RHC (right heart catherization) before they can get a script for Tyvaso or Tyvaso DPI for PH-ILD. See slide 11 from the presentation slides from a "Science Session" by UTHR. s1.q4cdn.com/284080987/files/doc_downloads/2021/02/19/UTHR_INCREASE_Combined_Deck_0204_2021_FINAL.pdfIf a person has ILD, the clinician might suspect concomitant PH, but a RHC is required to confirm a diagnosis of PH-ILD. A RHC is a significant procedure which can be done as an outpatient or as part of a hospital stay. Scheduling the RHC takes a little time so it's like a speedbump in the path toward obtaining a script for PH-ILD. Mike Benkowitz explained that quite a few patients with PH-ILD have never had a RHC because until now, there was no therapy. Until now, there was no purpose in confirming the diagnosis. |
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Post by mymann on Dec 18, 2022 14:28:04 GMT -5
A patient might need a RHC (right heart catherization) before they can get a script for Tyvaso or Tyvaso DPI for PH-ILD. See slide 11 from the presentation slides from a "Science Session" by UTHR. s1.q4cdn.com/284080987/files/doc_downloads/2021/02/19/UTHR_INCREASE_Combined_Deck_0204_2021_FINAL.pdfIf a person has ILD, the clinician might suspect concomitant PH, but a RHC is required to confirm a diagnosis of PH-ILD. A RHC is a significant procedure which can be done as an outpatient or as part of a hospital stay. Scheduling the RHC takes a little time so it's like a speedbump in the path toward obtaining a script for PH-ILD. Mike Benkowitz explained that quite a few patients with PH-ILD have never had a RHC because until now, there was no therapy. Until now, there was no purpose in confirming the diagnosis. Right Heart cath is much easier than Left Heart cath. Accessing the vein does not haveto deal with high pressure in comparison to the arterial cath. Less bleeding and less complications. |
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Post by uvula on Dec 18, 2022 14:30:55 GMT -5
I'm a non doctor.
If ph and ph-ilc are both treated with Tyvaso, why does it matter which disease you have?
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Post by Clement on Dec 18, 2022 16:37:18 GMT -5
PAH and PH-ILD
You have to be diagnosed for it in order for insurance to pay.
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Post by Clement on Dec 19, 2022 8:47:05 GMT -5
Screening for PH-ILD is described in more detail at tyvaso.com. "ILD symptoms can mask the symptoms of PH-ILD PH symptoms can be similar to those of ILD, making them hard to distinguish from ILD based on physical examination." www.tyvasohcp.com/ph-ild/about-ph-ild/screening/ |
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Post by prcgorman2 on Dec 28, 2022 3:46:25 GMT -5
Yikes, catheter in the heart. Surgical procedure. $$$ for hospitals is what it sounds like to me. The gov and the “powers that be” needing to whet their beaks.
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Post by hellodolly on Dec 28, 2022 10:27:31 GMT -5
What is the speedbump?
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Post by Clement on Dec 28, 2022 11:37:21 GMT -5
If you are driving and come to a speedbump, you slow a little, proceed over the bump, and go ahead.
If you are a doc and want to write a script for TDPI, you might have to go over the small hurdle (mostly scheduling) of a RHC, and if the Dx is confirmed, go ahead and write the script.
An electrocardiogram might also be in the path toward a script for TDPI. And Mike C said that the time from writing a script to getting a TDPI script filled is about a month because of paperwork.
I started this thread to discuss something that might slow the process of getting a script for TDPI. Why does this matter to me? I like to guess whether we are going to have explosive growth now (4Q 2022) or more metered over time.
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Post by Clement on Dec 28, 2022 11:39:34 GMT -5
"More metered over time." Aw heck, Mom, I want my thrills now. But what if UTHR can add the same net revs in the coming quarters as last quarter?
Linear growth example: UTHR had about $60 million* of TDPI net revs added last quarter. Let's suppose $60 million is added each quarter going forward. Straight line. If this went on for 4 more quarters from right now, TDPI would have a "blockbuster" run rate (annualized rate)! I can hope!
*based on assumed royalty rate of 10%
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Post by hellodolly on Dec 28, 2022 15:52:33 GMT -5
"More metered over time." Aw heck, Mom, I want my thrills now. But what if UTHR can add the same net revs in the coming quarters as last quarter? Linear growth example: UTHR had about $60 million* of TDPI net revs added last quarter. Let's suppose $60 million is added each quarter going forward. Straight line. If this went on for 4 more quarters from right now, TDPI would have a "blockbuster" run rate (annualized rate)! I can hope! *based on assumed royalty rate of 10% Would you use an asterisk* if it's characterized as "blockbuster" due to the speed bump? I get what you're saying but, by the same token if you have an HMO and are required to see your primary before getting an authorization to see a specialist, it might be a slow wake zone at best but the end result is still the same. I think that's what I'm trying to say. It's not really "a thing" to me. |
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