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Post by MnkdWASmyRtrmntPlan on Mar 1, 2023 14:32:49 GMT -5
I got sooo comfortable living over $5.
From 1/24 to today, 3/1. That's over 5 weeks that it has been over $5.
It looks like there were a LOT of $5.00 stop losses that activated today.
Did I miss any bad news?
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Post by mytakeonit on Mar 1, 2023 15:08:54 GMT -5
As I said before, eliminate all those stop losses ... because they will make you cry in the end.
But, that's mytakeonit
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Post by MnkdWASmyRtrmntPlan on Mar 1, 2023 15:15:11 GMT -5
As I said before, eliminate all those stop losses ... because they will make you cry in the end. But, that's mytakeonit Yes, definitely true, mtoi. At least if you're holding mnkd. As you would say ... time to load up.
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Post by peppy on Mar 1, 2023 15:16:59 GMT -5
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Post by hellodolly on Mar 1, 2023 15:22:48 GMT -5
Not a PWDs so, tell me, if you're on this $25 insulin, how much do you need per day/week/month to control your diabetes and how does that stack up with what you get from MNKD, each month? What are the dollars and cents here?
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Post by peppy on Mar 1, 2023 15:29:08 GMT -5
Not a PWDs so, tell me, if you're on this $25 insulin, how much do you need per day/week/month to control your diabetes and how does that stack up with what you get from MNKD, each month? What are the dollars and cents here? agedhippie, pipe up and I know you use pens. My understanding is a type 1 will use 1 vial of insulin a month. is that 10 millilitters or cc a month. Insulin vials have U-100 insulin. That means there are 100 units of insulin in each milliliter (mL) of insulin. Humalog® insulin comes in 3 mL (300 units) vials or 10 mL (1000 units) vials. The last I calculated Afrezza was selling for $1.09 a unit. Up from .79 a unit after Sanofi drop and sales force start.
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Post by lennymnkd on Mar 1, 2023 15:55:02 GMT -5
Well ! Is todays drop Lilly ? Big pharma will selling insulin As a lost leader .all the time complying with the administration’s wishes
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Post by peppy on Mar 1, 2023 16:08:00 GMT -5
Well ! Is todays drop Lilly ? Big pharma will selling insulin As a lost leader .all the time complying with the administration’s wishes At Lilly, insulin-making E. coli is grown in 50,000-liter tanks called fermentors. There are more than 5,000 tanks on site.According to Lilly, a batch of insulin from one fermentor could produce a year's supply of insulin for thousands of people. Small tubes of the bacteria have been stored in a freezer at minus 70 degrees Celsius (minus 94 degrees Fahrenheit) for decades. Whenever Lilly wants a fresh stash of Humulin, workers go to the freezer, pull out a tube from the master cell bank, thaw it out, and stimulate the bacteria to grow. Starting with a mere half gram of bacteria, the microorganisms begin to replicate prodigiously, doubling their numbers every 20 minutes or so. To jump-start insulin production, the researchers free up the insulin gene by adding a chemical called an inducer to the giant vat of teeming bacteria. The critters promptly begin to churn out insulin, holding the protein in clumps inside themselves. the purification scheme is to separate the bacteria from the broth. That's done with a centrifuge, a machine that spins very fast, forcing the bacteria into a pellet at the bottom of a vessel. The broth is then removed and replaced with a liquid containing a substance that breaks down cell membranes, helping release the insulin from its bacterial prison. At this point, the insulin still isn't actually insulin. It's "proinsulin," a longer inactive precursor of insulin. Insulin makers use an enzyme to carve out a section of proinsulin, leaving behind just the 51 amino acids of insulin proper. (The part that is snipped out is called C-peptide. columns are filled with various substances designed to separate insulin from other molecules based on differences in their electrical charge, acidity, size, and other characteristics. The insulin emerges from the columns alone. ==============================================================================================================
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Post by lennymnkd on Mar 1, 2023 16:45:56 GMT -5
Watch replay of Lilly ceo on CNBC .. just on .. see what he thinks about insulin “slow growth he’s moving on . Binden was tweeting about it today .
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Post by lennymnkd on Mar 1, 2023 17:48:54 GMT -5
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Post by sayhey24 on Mar 1, 2023 18:11:47 GMT -5
"Insulin is not a growth driver" - no kidding, I guess he saw the ABC trial results and knows the future for mealtime control is afrezza and NVO is getting icodec approved.
He is really excited about Mounjaro - lets hope CGMs get approved for 1 daily insulin on Medicare and we can get more people seeing their post meal numbers. Lets also hope Mike gets the study going he mentioned last week for the GLP1s, asap.
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Post by agedhippie on Mar 1, 2023 18:30:32 GMT -5
Not a PWDs so, tell me, if you're on this $25 insulin, how much do you need per day/week/month to control your diabetes and how does that stack up with what you get from MNKD, each month? What are the dollars and cents here? agedhippie , pipe up and I know you use pens. ... I use a couple of pens a month. If I was a Type 2 I would expect to be using between three and four times as much so 6 to 8 pens. The key thing here though is that $35 per month cap. If I was a Type 2 that would save me a lot of money. If was on a pump it would be a complete no-brainer financially as I could probably get by on one vial and that would be both my basal and bolus covered.
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Post by agedhippie on Mar 1, 2023 18:42:37 GMT -5
I guess he saw the ABC trial results and knows the future for mealtime control is afrezza and NVO is getting icodec approved. He is really excited about Mounjaro - lets hope CGMs get approved for 1 daily insulin on Medicare and we can get more people seeing their post meal numbers. Lets also hope Mike gets the study going he mentioned last week for the GLP1s, asap. LLY has it's own weekly basal going through approval as well so Icodec is unlikely to scare them. I think we are going to have to disagree how much CGMs will change the T2 landscape. For years now people there has been the "eat to your meter" mantra in the T2 world for exactly that - seeing the spike after you eat. You will see it as standard advice to T2s on diabetes forums. If you have reached the point of basal insulin you will already know that you spike after a meal. As to the ABC trial results; nobody knows what those are at the moment, it certainly isn't the results they published at ATTD. The ABC trial didn't include any mealtime challenge anywhere so it can't even be part of the trial, check the protocol if you don't believe me - clinicaltrials.gov/ct2/show/NCT05243628. TBH it doesn't really matter (it's not new so the endos won't care) - it's the big follow on trial that will matter.
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Post by mnlearner on Mar 1, 2023 18:53:09 GMT -5
"Not a PWDs so, tell me, if you're on this $25 insulin, how much do you need per day/week/month to control your diabetes and how does that stack up with what you get from MNKD, each month?
What are the dollars and cents here?"
I read what peppy said but still am unclear [read clueless] was to how the $35 cap for insulin compares for what an ave Afrezza would use in $ and cents. I am just a long invested and luckily not diabetic.
Thanks in advance for your help and kindness to this clueless person.
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Post by agedhippie on Mar 1, 2023 22:13:10 GMT -5
"Not a PWDs so, tell me, if you're on this $25 insulin, how much do you need per day/week/month to control your diabetes and how does that stack up with what you get from MNKD, each month? What are the dollars and cents here?" I read what peppy said but still am unclear [read clueless] was to how the $35 cap for insulin compares for what an ave Afrezza would use in $ and cents. I am just a long invested and luckily not diabetic. Thanks in advance for your help and kindness to this clueless person. Have a look at the "Wondering what the monthly cost breakdown is for a Type 1" a bit further down the page. There are some breakdowns in that thread.
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