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Post by gomnkd on Apr 3, 2015 10:15:05 GMT -5
I went back to my archives and found the survey I did with endo's and PCPs. I got feedback from 50-60 endos and another 50-60 PCP. Years back I gave a summary of it in my blog.Looking at the survey results and comparing it with NRx counts, it makes a lot of sense. Take a look at attachment for a sample response for one of the question. Not all endo's are going to jump at a chance to prescribe Afrezza. They'll start slow, prescribe for a handlful, wait for 3+ months, see some consistent A1C readings and then prescribe more. An endo is not going to ruin their practice by taking a chance that can screw the patient. I think Sanofi is making a mistake delaying the DTC. The push strategy only works to a point, you need the pull (demand from pt). Here is the summary for PCP Type 1 Ave. 33.5 Std. 27.5 and for Endo Ave. 18.5 Std. 17.3 Look at how endo's are way more conservative. Anecdotal evidence also points to that. I've not heard of a single pt who got prescribed Afrezza without pt asking for it.
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Post by jpg on Apr 3, 2015 10:21:06 GMT -5
Agreed endos are some of the most conservative docs out there. A big part of why many of them become endos is tied into their conservative nature. Also agree that it will be a slow process as you describe (I just didn't think it would be this slow).
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Post by gomnkd on Apr 3, 2015 10:21:55 GMT -5
Q: If Afrezza is approved, what percent of your Type 1 Diabetes pts would you prescribe the drug to? Please explain why.
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Post by gomnkd on Apr 3, 2015 10:31:55 GMT -5
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Post by silentbob on Apr 3, 2015 10:34:00 GMT -5
Look at how endo's are way more conservative. Anecdotal evidence also points to that. I've not heard of a single pt who got prescribed Afrezza without pt asking for it. Great post! I just made a post on the slow rollout before reading this, and what you state like it could be a major reason. Overall they're very good numbers though, if the docs follow through.
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Post by silentbob on Apr 3, 2015 10:34:53 GMT -5
Q: If Afrezza is approved, what percent of your Type 1 Diabetes pts would you prescribe the drug to? Please explain why. Not sure I grasp this graph, could you clarify? What is on the vertical axis?
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Post by gomnkd on Apr 3, 2015 10:38:53 GMT -5
Q: If Afrezza is approved, what percent of your Type 1 Diabetes pts would you prescribe the drug to? Please explain why. Not sure I grasp this graph, could you clarify? What is on the vertical axis? Horizontal axis is % of Type 1 patients. Vertical (Y) axis is % of endos (blue) and pcp (red). Remember that sampling ain't too great, but I remember sending to 100 + 100 docs, and got 60% response rate.
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Post by babaoriley on Apr 3, 2015 10:39:28 GMT -5
Don't forget also, that we heard that DTC advertising is best begun only after docs are visited by reps and become somewhat familiar (if not totally comfortable) with the drug. Hope we get some TV ads, I would love to our debate over how bad or good they are - I'm sure of one thing, there will be a difference of opinion!
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Post by silentbob on Apr 3, 2015 10:53:07 GMT -5
Horizontal axis is % of Type 1 patients. Vertical (Y) axis is % of endos (blue) and pcp (red). Remember that sampling ain't too great, but I remember sending to 100 + 100 docs, and got 60% response rate. Thanks, I get it now! I am assuming all endo's got a SNY visit by now. Now if we assume all scripts were written by an endo then on average less then only one in five endo's have written ONE script so far. This is a lot less then what we would expect from your numbers. Are all of them just waiting for the herd to lead them? Or is this more because of the insurance issues? Interesting to think about...
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Post by harryx1 on Apr 3, 2015 10:55:59 GMT -5
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Post by gomnkd on Apr 3, 2015 11:04:31 GMT -5
Google sales trends are clouded by investors queries. Brentie alone would account for half of that search in that graph (just kidding brentie).
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Post by harryx1 on Apr 3, 2015 11:10:12 GMT -5
I know it's not perfect but it's probably the best we can compare with DTC ads with similar time frames of drug approvals in the same space.
Also if you scroll down to related searches you can click on each individual term and see additional terms searched that relate to the initial term.
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Post by saxcmann on Apr 3, 2015 11:47:29 GMT -5
Horizontal axis is % of Type 1 patients. Vertical (Y) axis is % of endos (blue) and pcp (red). Remember that sampling ain't too great, but I remember sending to 100 + 100 docs, and got 60% response rate. Thanks, I get it now! I am assuming all endo's got a SNY visit by now. Now if we assume all scripts were written by an endo then on average less then only one in five endo's have written ONE script so far. This is a lot less then what we would expect from your numbers. Are all of them just waiting for the herd to lead them? Or is this more because of the insurance issues? Interesting to think about... one clinic with 3 three endos have done 50+ Rxs so far. Less than half of endos have been approached by sny yet. Less than 20 samples given to clinic. plenty of coupons given...are coupons recorded on scripts? If not then we have our answer for slow scripts. Plus it takes time for doctors to get results from first patients and time for scheduling new patients. One more thing...90% type 1 and 50% type 2 should get Rxs eventually, imo.
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Post by tigiron on Apr 3, 2015 12:20:38 GMT -5
one clinic with 3 three endos have done 50+ Rxs so far. Less than half of endos have been approached by sny yet. Less than 20 samples given to clinic. plenty of coupons given...are coupons recorded on scripts? If not then we have our answer for slow scripts. Plus it takes time for doctors to get results from first patients and time for scheduling new patients. One more thing...90% type 1 and 50% type 2 should get Rxs eventually, imo. Source? Any info on this superstar clinic? Any more details regarding the info you provided?
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Post by tigiron on Apr 3, 2015 12:28:00 GMT -5
When did they launch DTC ads for Invokana and Farxiga? Just wondering the if the jump in interests were due to DTC or the approval / launch news.
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