|
|
Post by savzak on May 4, 2015 18:54:56 GMT -5
I'm a poor excuse for a TV watcher but I just saw a Novalog commercial that I don't remember seeing before. "Used by millions since 2001". Honestly, I don't remember ever seeing any Novalog commercial before so I'm a sad observer here. But I just wondered whether this is part of the defense against Affreza.
|
|
|
|
Post by jfl on May 5, 2015 10:03:40 GMT -5
Wow! I haven't seen the ad, but the wording ("since 2001") certainly sounds like it's aimed against Afrezza--the new drug on the block.
Perhaps, one of Sanofi's Afrezza ads should state, "Tested safe and effective since 2004".
|
|
|
|
Post by savzak on May 5, 2015 10:11:45 GMT -5
|
|
|
|
Post by mnkdorbust on May 5, 2015 10:15:26 GMT -5
I'm not much of a tv watcher but over the last year have noticed diabetes medication ads. It could be that i'm more aware since i'm invested in MNKD but i don't believe i've ever noticed them before.
|
|
|
|
Post by jfl on May 5, 2015 10:48:43 GMT -5
I'm not much of a tv watcher but over the last year have noticed diabetes medication ads. It could be that i'm more aware since i'm invested in MNKD but i don't believe i've ever noticed them before. Rarely watch TV myself. Ever since The Great YMB Migration, I get all the entertaining drama on this MNKD forum. When I do watch, I've seen an ad for Januvia. |
|
|
|
Post by kball on May 5, 2015 11:01:35 GMT -5
The Victoza ad with NBA legend Dominique Wilkens have caught my eye during the nba playoffs.
Big hoops fan and didnt know dominique was diabetic. And it seemed a little different than other diabetes med ads as he is somewhat famous. and the others i've seen or been mildly aware of seem to use actors
|
|
|
|
Post by bradleysbest on May 5, 2015 12:19:02 GMT -5
Listen to the "side effects" on the Dominique commercial. Most of the 2 minute commercial time is spent on them including death!
|
|
|
|
Post by harryx1 on May 5, 2015 14:27:15 GMT -5
Here's a new one that's showing up in search results: Attachment DeletedAnd when you click on it, you end up on a page about Novolog talking about it's Pharmacokinetics... Attachment Deleted |
|
|
|
Post by jpg on May 5, 2015 14:39:54 GMT -5
Very interesting... One off these in isolation is not a big deal but taken together Novo really seems to be countering the possibility of Afrezza upsetting the status quo.
Very very interesting!
|
|
|
|
Post by otherottawaguy on May 5, 2015 15:57:48 GMT -5
They didn't show a timeline on the second graph, be interested to see how Afrezza would snuggle inside the other three curves.
OOG
|
|
|
|
Post by harryx1 on May 5, 2015 16:04:34 GMT -5
|
|
|
|
Post by otherottawaguy on May 5, 2015 16:09:31 GMT -5
Wonder if we have enough stats lying around to produce our own graphic? One that shows afrezza as well.
With a caption that looks like an after thought talking about it being an inhaled option.
|
|
|
|
Post by harryx1 on May 5, 2015 16:20:36 GMT -5
Wonder if we have enough stats lying around to produce our own graphic? One that shows afrezza as well. With a caption that looks like an after thought talking about it being an inhaled option. Do you mean this graph? Attachment Deleted |
|
|
|
Post by compound26 on May 5, 2015 16:36:53 GMT -5
If that chart depicts the actions of Afrezza and healthy people insulin responses accurately, it appears the best time to take Afrezza is 15 minutes after one starts eating.
This chart confirms what Al Mann has said about the timing of Afrezza (I recall Al Mann said in his speeches that the best time to take Afrezza is 15 minutes after one starts eating).
|
|
|
|
Post by compound26 on May 5, 2015 16:41:46 GMT -5
SF: Was that when you changed to the new device? AM: No, I think that a problem during the trials was that some patients took their dose of Afrezza even before starting to eat. The trial protocols called for Afrezza to be dosed "at the beginning of the meal," but sometimes it was taken even before. We need to do additional trials to gain more experience with optimized dosing times. Actual ingestion of food in most meals in the United States except in restaurants takes only about 30 minutes, so I believe that the first Afrezza dose really ought to be taken ten or fifteen minutes after starting to eat. For a longer meal, which is not very common, a second dose might be taken fifty or sixty minutes after starting to eat. For a long feast that lasts for an hour and a half or more, I suggest a third dose be taken at maybe one and a half hours after start. Interestingly I believe the size of all those doses should probably be the same for most patients. Unfortunately the trial protocols called for dosing at the beginning of the meal so we will need to do more trials to be able to gain FDA label approval of optimized dosing. An Exclusive Interview with Al Mann, Founder and CEO, Mannkind Corp. www.diabetesincontrol.com/articles/85-clinical-gems/16894-an-exclusive-interview-with-al-mann-founder-and-ceo-mannkind-corp |
|
