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Post by harryx1 on Jul 26, 2015 12:19:49 GMT -5
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Post by babaoriley on Jul 26, 2015 13:13:51 GMT -5
The last few paragraphs of that article sure plug Toujeo's ability to reduce hypos.
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Post by mnholdem on Jul 26, 2015 13:57:43 GMT -5
If only Afrezza could do that...  |
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Post by joeypotsandpans on Jul 26, 2015 14:37:35 GMT -5
Ok Harry, you're slipping....you missed this one and it really hits home regarding providers and their perception of patient compliance with regard to starting insulin treatment: www.ajmc.com/journals/issue/2015/2015-vol21-n6/provider-behavior-and-treatment-intensification-in-diabetes-careThe last line in this excerpt paragraph from posted article link goes back to something I mentioned previously that ruffled some of the medical professional feathers on here and was stricken from the record, it was meant with good intentions but was too sensitive a subject I guess so I won't mention "that word" again but you'll get the gist of it from this....for the Dr's on board please don't take this personally or the wrong way again (it certainly isn't directed at our illustrious board members ) A seminal report by Phillips13 led to numerous studies focusing on the role of “clinical inertia” in healthcare delivery, including diabetes care. As conceptualized by Phillips et al, clinical inertia is the “failure of healthcare providers to initiate or intensify treatment when indicated.” This failure is postulated to be fueled by a combination of provider, patient, and organizational factors.14 The Phillips paper was a driving force behind the publication of a large body of literature whose findings suggested that the gap between what is recommended in diabetes care and what is actually acted upon during a clinical encounter reflects widespread deficiencies in quality of care. This line of thinking equates lack of action with lack of quality. It goes on to argue that these apparent deficiencies result in a considerable amount of potentially avoidable morbidity and mortality in an ever-increasing diabetic population, and that aggressive action is needed to encourage physicians to engage in prescribing behaviors that are more effective in helping patients achieve standard clinical targets. One report even likens failure to intensify treatment to a medical error.15 - See more at: www.ajmc.com/journals/issue/2015/2015-vol21-n6/provider-behavior-and-treatment-intensification-in-diabetes-care/P-3#sthash.QuVEiHtb.dpuf |
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Post by liane on Jul 26, 2015 14:59:36 GMT -5
joey,
I'm really baffled. I don't see any posts by you that were deleted for referencing anything such as medical error. Only a handful that were caught in the crossfire of other transgressions.
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Post by babaoriley on Jul 26, 2015 15:35:08 GMT -5
"Ok Harry, you're slipping....you missed this one..." Wow, Joey, you're a pretty brave hombre! From what I've seen, Harry can probably document every misstep you've ever made in you life, and probably produce video to back it up! |
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Post by Deleted on Jul 26, 2015 16:08:44 GMT -5
Great work Harry and good information in the article. Below is a cut and paste for those who may not have had time to look at all of it and as I have said before, perhaps the biggest value of Afrezza is the combination of ease of compliance, improved patient health and massive reduction in long term health complications and associated costs. There is no insulin that performs like Afrezza. Hopefully Sanofi gets the label upgraded Q1 of next year. If so, all bets for MNKD share price are off and if Sanofi doesn't write the check, someone else will. Yet pharmaceutical companies continue developing treatments like Toujeo and Afrezza because a huge percentage of diabetics fail to control their condition with current options. A recent study that examined records from more than 43,000 patients found that less than 55% of all Americans who have been diagnosed with diabetes, and prescribed medication to control blood sugar, actually manage to keep their A1C level under 7%.The main cause of this problem seems to be patient behavior. Studies have found that patient adherence to oral treatment protocols can range from more than 90% down to just over 50%. Strict adherence to guidelines concerning injectable medications and proper diet tends to be lower, while strict ad-herence to guidelines concerning moderate, regular exercise and blood sugar checks is downright rare. The chance that any patient will adhere perfectly to a complex regimen is low, and studies of people with all types of chronic disease have typically found that only about half of them will make a serious effort to manage their condition.8 The consequences of this behavior are dire. Diabetes is the nation’s seventh-leading cause of death. It increases the risk of stroke (by 50%), heart attack (by 80%), and death from cardiovascular disease (by 70%). It is also the leading cause of kidney failure and non-traumatic lower limb amputation. The American Diabetes Association estimates that the direct medical cost of treating diabetes reached $176 billion in 2012, and indirect costs such as lost productivity add-ed another $69 billion to the tally.Studies have demonstrated that increased adherence to a treatment regimen can reduce A1C levels and many other studies have shown that A1C reductions prevent complications. A 1% reduction in A1C is associated with a 14% reduction in the risk of heart attack and a 40% reduction in the risk of eye, kidney, and nerve disease. (Logic says that better adherence would also slash healthcare costs, but the findings from research on that topic are mixed.10) |
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Post by joeypotsandpans on Jul 26, 2015 17:28:15 GMT -5
joey, I'm really baffled. I don't see any posts by you that were deleted for referencing anything such as medical error. Only a handful that were caught in the crossfire of other transgressions. It was the one referencing the one that I just reminded you of in the PM |
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