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Post by brotherm1 on Jun 19, 2016 3:33:26 GMT -5
Assuming RLS is planning a cannabis product using technosphere (big assumption, please just go with it)... How would the delivery be better than a vaping device that just delivers the THC. I'm just trying to understand the benefit here. I get smoking is bad because of cancer. But what about vaping? To get a proper/prescibed dosage Also, I think eventually the active ingedients in marijuana that create a high will eventually be separated from other ingedients in it that are of medicinal use other than an altered state of consciousness, if they are not already in some forms?
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Post by lakers on Jun 19, 2016 4:24:30 GMT -5
I got home from work today and pulled the property records from King County (Seattle WA) for the address Receptor Life Sciences is registered to (2578 Constance DR W, Seattle, 98199). www.sos.wa.gov/corps/search_detail.aspx?ubi=603568334The owner of this residence is Traci Carman (CFO of EMP museum founded by Paul Allen and listed director of Receptor Life Sciences) In this 2012 report Greg Wesner, the attorney listed as Receptor Life Science's director, is listed as a supporter of the EMP museum, founded (and funded) by Paul Allen (CFO Traci Carman) Gregory Wesner's LinkedIn summary says that he has served pro bono as counsel to the Experience Music Project (EMP) in its community outreach efforts (Founded by Paul Allen, CFO Traci Carman) A company called ELC DEVELOPMENT lists both Paul Allen and Traci Carman as directors. Mr. Wesner specializes in intellectual property law. m.reddit.com/r/wallstreetbets/comments/4b6b5l/i_dont_mean_to_be_annoying_a_very_brief_update_to/
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Post by peppy on Jun 19, 2016 8:16:30 GMT -5
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Post by mnkdfann on Jun 19, 2016 9:32:07 GMT -5
I got home from work today and pulled the property records from King County (Seattle WA) for the address Receptor Life Sciences is registered to (2578 Constance DR W, Seattle, 98199). www.sos.wa.gov/corps/search_detail.aspx?ubi=603568334The owner of this residence is Traci Carman (CFO of EMP museum founded by Paul Allen and listed director of Receptor Life Sciences) In this 2012 report Greg Wesner, the attorney listed as Receptor Life Science's director, is listed as a supporter of the EMP museum, founded (and funded) by Paul Allen (CFO Traci Carman) Gregory Wesner's LinkedIn summary says that he has served pro bono as counsel to the Experience Music Project (EMP) in its community outreach efforts (Founded by Paul Allen, CFO Traci Carman) A company called ELC DEVELOPMENT lists both Paul Allen and Traci Carman as directors. Mr. Wesner specializes in intellectual property law. m.reddit.com/r/wallstreetbets/comments/4b6b5l/i_dont_mean_to_be_annoying_a_very_brief_update_to/Thanks, but none of this is new. The same info (your link and more) was posted months ago all over ... even on this very forum (and in this very thread, see posts by iam2sekc4u2002, myself, and others) in January.
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Post by Deleted on Jun 19, 2016 11:59:45 GMT -5
Assuming RLS is planning a cannabis product using technosphere (big assumption, please just go with it)... How would the delivery be better than a vaping device that just delivers the THC. I'm just trying to understand the benefit here. I get smoking is bad because of cancer. But what about vaping? No one knows for sure what vaping causes long term health wise. Vaping also changes the high.
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Post by lakers on Jun 19, 2016 12:08:15 GMT -5
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Post by Deleted on Jun 19, 2016 13:51:06 GMT -5
This is old news, but not old news regarding the RLS speculation with marijuana and Paul Allen/Microsoft: •James Shively— Diego Pellicer* www.prnewswire.com/news-releases/diego-pellicer-announces-the-grand-opening-of-flagship-store-in-seattle-300245473.html—Quotes from article: -Diego Pellicer Worldwide Inc. is a real estate and a consumer retail development company that is focused on developing Diego Pellicer as the world's first "premium" marijuana brand by adhering to the highest quality and standards for its facilities along with both cannabis and non-cannabis products. The company's initial focus is to acquire and develop legally compliant real estate locations for the purposes of leasing them to state licensed companies in the cannabis industry. Diego does not grow or sell marijuana or marijuana infused products in the early stages of the plan. -The company's second, branded retail location in Denver, Colorado is in the final stages of tenant improvement and build out and is anticipated to open in the third quarter of 2016. * www.cbsnews.com/news/former-microsoft-exec-tries-his-luck-at-building-marijuana-brand/—Quote from article: Mark Kleiman, who heads the team hired to be Washington's official marijuana consultant, responded on his blog: "It was inevitable that the legalization of cannabis would attract a certain number of insensate greedheads to the industry." Shively's ambitions — "We are Big Marijuana," he proclaimed — don't merely raise questions about what marijuana legalization might look like in the long run and whether large corporations will come to dominate. He also risks getting himself indicted. — "Bill Gates of Marijuana" www.geekwire.com/2012/product-manager-pot-microsoft-marijuana/
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Post by peppy on Jun 20, 2016 6:02:13 GMT -5
Assuming RLS is planning a cannabis product using technosphere (big assumption, please just go with it)... How would the delivery be better than a vaping device that just delivers the THC. I'm just trying to understand the benefit here. I get smoking is bad because of cancer. But what about vaping? No one knows for sure what vaping causes long term health wise. Vaping also changes the high. xoxoxoxo, I believe the initial target here RLS would be the epilepsy market, legal to do in the state and under the laws. Technosphere titrated, CBD's delivered per dream boat to control epileptic seize is my conjecture. We have seen the video taped and testimonial proof. Clinical trials could determine, 300 seizures a week to 1 seizure a week pretty quickly.
Added; Additionally it has become my understanding the some of the thc acids that are "anti-inflammatory", as in arthritis helpful, are heat sensitive. it is the heat that turns them into thc, the plan may be to circumvent that problem. pep
circumvent from circumcise, oh, ha ha
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Post by brotherm1 on Jul 4, 2016 19:41:28 GMT -5
So Mango broght a reminder to me today of RLS in another thread that was locked. Does anyone know what would be the earliest possible time under current state(s) medical marijuana laws an inhalable medical cannabis product could be approved by the FDA and marketed? Also, are there any foreign countries where an inahable cannabis could be approved to market in less time than in the US? Don't know if a discussion on theae subjects was ever thoroughly discussed and concluded or not. As much as I'd like to, I can't possibly find time to search and read back through all the posts herein and possibly through other threads (perhaps there is an advanced search feature I am not aware of to allow seachimg by topic and several consecutive words in the thread). Thus I am just wondering if anyone off the top of their head might know the answers to these questions?
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Post by nylefty on Jul 4, 2016 21:57:30 GMT -5
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Post by Deleted on Jul 5, 2016 2:27:38 GMT -5
—The FDA approved Marinol, which is synthetic THC. —My state has been growing and supplying marijuana since the 70s to select patients in the US under a federally funded cannabis program (NIDA). Sadly, the compassionate IND act was closed in the 90s and only four patients to this day still receive free marijuana provided by the federal government. —Interestingly enough, Andrea Leone-Bay and Ole Miss have attended the same drug delivery conference before. And not too long ago might I add. Not speculating, just pointing it out. —Also,GW Pharmaceuticals has phase 3 clinical trials. My neighboring state, TN, is actually hosting one through the St Jude Children's Research Hospital
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Post by brotherm1 on Jul 5, 2016 9:34:45 GMT -5
Mango - GW Pharma, how are they testing cannabis in this phase three? Is it smoked, in pill form, or other? Inhaling a hard form cannabis could be difficult. Is RLS perhaps working to take away certain elements from the marijuana plant for medical use in the Technosphere device? If so, how long before it could be approved by the FDA? If I recall correctly, at least some of this regarding plant extracts and technosphere was discussed before on this board and perhaps even in this very thread. I don't think anyone had any conclusive answers, though I could of course be wrong. Are you perhaps aware of what exactly GW Pharma is trying to get approved with this phase three? Is it perhaps in the form of pills containing extracts of the plant? Oils? Other? Or are they perhaps testing with inhalable extracts?
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Post by nylefty on Jul 5, 2016 10:30:40 GMT -5
Are you perhaps aware of what exactly GW Pharma is trying to get approved with this phase three? Is it perhaps in the form of pills containing extracts of the plant? Oils? Other? Or are they perhaps testing with inhalable extracts? It's a "child-friendly syrup," according to Reuters (Google Is Your Friend). www.reuters.com/article/us-gw-pharma-cannabis-idUSKCN0WG16Z
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Post by brotherm1 on Jul 5, 2016 11:11:20 GMT -5
Are you perhaps aware of what exactly GW Pharma is trying to get approved with this phase three? Is it perhaps in the form of pills containing extracts of the plant? Oils? Other? Or are they perhaps testing with inhalable extracts? It's a "child-friendly syrup," according to Reuters (Google Is Your Friend). www.reuters.com/article/us-gw-pharma-cannabis-idUSKCN0WG16ZThanks Lefty. I thought perhaps Mango was on top of all that. Google is my friend but time at the time is not. Interesting that it is a child friendly syrup. I'll check it out when time permits.
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Post by matt on Jul 5, 2016 11:12:00 GMT -5
—The FDA approved Marinol, which is synthetic THC.
That is an interesting point. The FDA and similar regulatory agencies around the world are very concerned about definition of, and delivery of a therapeutic dose. One reason inhaled medications are frowned upon is the variability in the amount of drug delivered to the lung as this can vary widely due to technique by the user. The more potent the dose, the more important precise delivery becomes.
The other matter is potency of the dose. If the active ingredient in a drug is manufactured synthetically (and almost any molecule can be made by a good organic chemist) then the potency is known with a high degree of certainty. Compare that with a plant grown by Farmer Jones in one state with different soil, water, and sunlight compared with that grown by Farmer Smith 1,000 miles away. Both can plant the same seed, but they get very different potencies. Processing plant material to extract specific proteins is a difficult task so pharma companies will wind up using synthetic material just because it is cheaper and easier in the long run.
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