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Post by sportsrancho on Apr 4, 2016 18:25:36 GMT -5
inappropriately bearcatbob, in this moment, I am considering changing my message board nickname to, "scratchhiseyesoutpeppy"
(the devil made me do it)
Do you not think the answer to that question is the key to our financial problems? How can we have the worlds greatest drug and a company going towards BK? Serious people need to know the answer to that question. There is a HUGE disconnect between what we want to believe and financial realities of the markets. Facts are sometimes so damn tough. Awareness!
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Post by bearcatbob on Apr 4, 2016 18:31:42 GMT -5
Well peppy - how about you try to explain these "facts" to me? I think I am a pretty smart guy. Smart enough to recognize that money is the real judge of a company's prospects. Please tell me why money is wrong in the case of MNKD. I think your answer might be really interesting.
Trust me - there is something wrong here - and I have the financial losses to prove something is missing in this love affair with MNKD. Now - I admit I was not smart enough originally to see the problem - but I am sure as hell smart enough to see there is a problem.
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Post by spiro on Apr 4, 2016 19:10:52 GMT -5
Bearcat, that's a tough question to answer, because IMO, there are quite a few factors that can be attributed to Afrezza's slow sales start. IMO the biggest factor was a total marketing failure by Sanofi. How can a new diabetes insulin be successful when most diabetics to this day, don't even know that it exists? Then, Sanofi's refusal to drop the price of Afrezza, after most insurance companies refused to start coverage on the drug. Sanofi, obviously knew by last April, that a price drop was necessary, so why the refusal? it is Spiro's opinion that MNKD even with limited resources will be able to prove within 4 -6 month's that Sanofi was incompetent in their handling of Afrezza sales and marketing. It is most likely that Sanofi will try their best to make some sort of settlement with MNKD before the world finds out about what a game changing drug Afrezza could be. Now, let Spiro put some blame on two more groups. First, our stubborn doctors who have become very regimented in their treatment techniques for diabetes and are unwilling to change course, even if their results are inadequate. How many times do we hear about an A1c of 8.5 and nothing is changed by the doctor? Second, let's put some blame on Diabetics, if they even know they are diabetic. Too many diabetics are unwilling to be proactive and get involved in their diabetes treatment with their doctor. Aggressive advertising will find proactive diabetics. Sanofi didn't even try to find them. Diabetes is a nasty disease, it can take away your eyesight, you toes, kill your pancreas and basically destroy your life. I could list a lot more more, but I'm done for now.
Spiro here, I'm going to eat a couple of peeps and then puff 4 units. Damn, how does Liane know everything?
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Post by peppy on Apr 4, 2016 19:15:34 GMT -5
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Post by blindhog1 on Apr 4, 2016 19:26:52 GMT -5
MNKD is only going to issue a press release tomorrow per their twitter page. Doubt it will be XMAS like tomorrow. Just looking for a lil good news as far as their plan moving forward. To confirm: $MNKD to issue PR on or about 4/5 re: return of rights of #Afrezza. There is no planned statement or PR re: RLS expected 4/5.
Damn you're so good. If I had a Crystal Ball I'd let you read it...actually I do have a crystal ball and it says: "To confirm: $MNKD to issue PR on or about 4/5 re: return of rights of #Afrezza. There is no planned statement or PR re: RLS expected 4/5."
Damn it's accurate.
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Post by nylefty on Apr 4, 2016 19:38:44 GMT -5
inappropriately bearcatbob, in this moment, I am considering changing my message board nickname to, "scratchhiseyesoutpeppy"
(the devil made me do it)
Do you not think the answer to that question is the key to our financial problems? How can we have the worlds greatest drug and a company going towards BK? Serious people need to know the answer to that question. There is a HUGE disconnect between what we want to believe and financial realities of the markets. Facts are sometimes so damn tough. It's very simple. The Sanofi CEO who signed the marketing deal with MannKind was enthusiastic about Afrezza and would have made it a success. But he was fired and his replacement sandbagged Afrezza. Period.
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Post by kball on Apr 4, 2016 19:39:33 GMT -5
FOR IMMEDIATE RELEASE:
Mannkind today announces the handback of our first and only FDA approved drug Afrezza, (after a year of dicking around by Sanofi), which we are currently ill prepared to handle financially, as well as ill equipped to market successfully on our own. God help us all.
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Post by bearcatbob on Apr 4, 2016 19:47:08 GMT -5
Far too easy. If you are right then MNKD should be beating off the offers from those smarter than the ex CEO of Sanofi. Excuse me if I am missing that line.
Look - I believed and was wrong. Money talks - and I do not like what it is saying. To ignore the voice of money to me is foolish.
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Post by peppy on Apr 4, 2016 19:50:55 GMT -5
Far too easy. If you are right then MNKD should be beating off the offers from those smarter than the ex CEO of Sanofi. Excuse me if I am missing that line. Look - I believed and was wrong. Money talks - and I do not like what it is saying. To ignore the voice of money to me is foolish. Now you have it. Matt does not like to announce things prematurely as you know.
mnkd had to get the rights back, all of them.
I do hear you, at $1.69 MNKD is a failure. yes. on a ventilator, we are starting to wean the pressures, and the O2. we will get an arterial blood gas in the morning. The patient is not dead.
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Post by sportsrancho on Apr 4, 2016 19:52:46 GMT -5
Bearcat, that's a tough question to answer, because IMO, there are quite a few factors that can be attributed to Afrezza's slow sales start. IMO the biggest factor was a total marketing failure by Sanofi. How can a new diabetes insulin be successful when most diabetics to this day, don't even know that it exists? Then, Sanofi's refusal to drop the price of Afrezza, after most insurance companies refused to start coverage on the drug. Sanofi, obviously knew by last April, that a price drop was necessary, so why the refusal? it is Spiro's opinion that MNKD even with limited resources will be able to prove within 4 -6 month's that Sanofi was incompetent in their handling of Afrezza sales and marketing. It is most likely that Sanofi will try their best to make some sort of settlement with MNKD before the world finds out about what a game changing drug Afrezza could be. Now, let Spiro put some blame on two more groups. First, our stubborn doctors who have become very regimented in their treatment techniques for diabetes and are unwilling to change course, even if their results are inadequate. How many times do we hear about an A1c of 8.5 and nothing is changed by the doctor? Second, let's put some blame on Diabetics, if they even know they are diabetic. Too many diabetics are unwilling to be proactive and get involved in their diabetes treatment with their doctor. Aggressive advertising will find proactive diabetics. Sanofi didn't even try to find them. Diabetes is a nasty disease, it can take away your eyesight, you toes, kill your pancreas and basically destroy your life. I could list a lot more more, but I'm done for now. Spiro here, I'm going to eat a couple of peeps and then puff 4 units. Damn, how does Liane know everything? To the word exactly how I see it! One of the best posts I have ever read! I've always thought of Spiro as in-the-know. Because he just flat out knows!
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Post by nylefty on Apr 4, 2016 19:53:55 GMT -5
Far too easy. If you are right then MNKD should be beating off the offers from those smarter than the ex CEO of Sanofi. Excuse me if I am missing that line. Look - I believed and was wrong. Money talks - and I do not like what it is saying. To ignore the voice of money to me is foolish. How do you know that MannKind won't be getting offers? Under the Sanofi agreement MannKind was forbidden to negotiate with any other company about Afrezza until tomorrow. And my point was that the ex CEO of Sanofi WAS "smart" about Afrezza -- so we don't need anyone "smarter."
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Post by jerrys on Apr 4, 2016 20:46:38 GMT -5
Bearcat, that's a tough question to answer, because IMO, there are quite a few factors that can be attributed to Afrezza's slow sales start. IMO the biggest factor was a total marketing failure by Sanofi. How can a new diabetes insulin be successful when most diabetics to this day, don't even know that it exists? Then, Sanofi's refusal to drop the price of Afrezza, after most insurance companies refused to start coverage on the drug. Sanofi, obviously knew by last April, that a price drop was necessary, so why the refusal? it is Spiro's opinion that MNKD even with limited resources will be able to prove within 4 -6 month's that Sanofi was incompetent in their handling of Afrezza sales and marketing. It is most likely that Sanofi will try their best to make some sort of settlement with MNKD before the world finds out about what a game changing drug Afrezza could be. Now, let Spiro put some blame on two more groups. First, our stubborn doctors who have become very regimented in their treatment techniques for diabetes and are unwilling to change course, even if their results are inadequate. How many times do we hear about an A1c of 8.5 and nothing is changed by the doctor? Second, let's put some blame on Diabetics, if they even know they are diabetic. Too many diabetics are unwilling to be proactive and get involved in their diabetes treatment with their doctor. Aggressive advertising will find proactive diabetics. Sanofi didn't even try to find them. Diabetes is a nasty disease, it can take away your eyesight, you toes, kill your pancreas and basically destroy your life. I could list a lot more more, but I'm done for now. Spiro here, I'm going to eat a couple of peeps and then puff 4 units. Damn, how does Liane know everything? Why do you say Sanofi refused to lower the price? Has MNKD ever said that? Did MNKD ever bring up that up at any of the JAC meetings? Moreover, based on data from MNKD's filings, Sanofi appears to have spent 200-300 million on afrezza, yet couldn't manage more than 10 million dollars in revenues. How far in the hole should they have been expected to go before folding their hand? Is there even any evidence that lowering the price would have achieved better insurance coverage and/or significantly improved revenues?
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Post by sluggobear on Apr 4, 2016 20:47:49 GMT -5
Far too easy. If you are right then MNKD should be beating off the offers from those smarter than the ex CEO of Sanofi. Excuse me if I am missing that line. Look - I believed and was wrong. Money talks - and I do not like what it is saying. To ignore the voice of money to me is foolish. Yes it would be nice if there was a direct relationship between the individual experiences of Afrezza users and the SP of MNKD. Obviously it takes more than that (Afrezza being a really great drug) to drive sales and generate revenues. I think the barriers including the FEV1, PA's, and mostly lack of insurance coverage, have killed the market potential. That's why I hope they announce that "Mannkind will be supplying Afrezza AT COST to all Medicaid recipients who require insulin" and "We will offer Afrezza at pricing that circumvents insurance companies completely." But what do I know?
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Post by spiro on Apr 4, 2016 21:34:17 GMT -5
Jerrys,
During a discussion with Matt last October, I asked Matt, since the cost to manufacture Afrezza is less than $40 per box or so, ( he interrupted and said , depending on volume, it could be less than that ) why hasn't Sanofi lowered the price? He responded, That's what we would like to know? Also, do you really need evidence, that lowering the price of Afrezza to $150 per box, would have generated more insurance coverage and increased sales?
Spiro here, listen, Afrezza is a drug, lower the price, get user's hooked on it, then gradually raise the price again in a year or so.
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Post by bradleysbest on Apr 4, 2016 22:34:26 GMT -5
Excellent post! Plenty of reason for optimism starting tomorrow...
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