|
Post by wgreystone on Jan 22, 2017 1:07:11 GMT -5
Great write-up about MNKD's status. I just thought it missed an important point: why doctors do not actively prescribe Afrezza yet. It has been on market for two years. Most endos should already know about it, and it shouldn't be hard for endos to understand the unique PK profile of Afrezza. What is still holding them back from prescribing to at least a subset of diabetic patients?
|
|
|
Post by cedafuntennis on Jan 22, 2017 2:30:13 GMT -5
CCI. You said: "I believe that Matt has many “irons in the fire” when it comes to raising cash ". You mean like his "embarrassment of riches" BS? Matt had sooo many chances to raise good cash with little dilution if he really knew what he was doing. He missed every single opportunity at doing that.
Afrezza sales are dropping and Matt, Mike and their people seem totally uninterested in doing much about that. I am particularly upset as I spent quite some political capital to get them a presentation at City of Hope in late December 2016 and until now, after many contacts from my side via Tweeter and email, nobody has contacted the hospital. There are endos there who learned about Afrezza online, yes online as NOBODY ever contacted them who are asking for a presentation but Mannkind is apparently too busy to waste time with such a minute lead. This behaviour is totally explainable to me. Someone gives them a great presentation opportunity and they don't even bother to call to schedule a date in over 3 weeks. At 103 scripts per month, even 3 scripts extra is 3%... When we were dreaming about 200,000 scripts a month, this already sounds like a joke to me after 4 years invested with these guys...
|
|
|
Post by afrezzamiracle on Jan 22, 2017 3:15:26 GMT -5
Cedafuntennis, it makes me sick that they haven't jumped all over that lead you handed them on a silver platter. That is very telling about why we are in the pathetic sad state we currently find ourself in. That is simply inexcusable. If there is ANY doctor anywhere, any time that wants to hear about AFREZZA management should be all over it.
|
|
|
Post by mango on Jan 22, 2017 3:58:11 GMT -5
CCI. You said: "I believe that Matt has many “irons in the fire” when it comes to raising cash ". You mean like his "embarrassment of riches" BS? Matt had sooo many chances to raise good cash with little dilution if he really knew what he was doing. He missed every single opportunity at doing that. Afrezza sales are dropping and Matt, Mike and their people seem totally uninterested in doing much about that. I am particularly upset as I spent quite some political capital to get them a presentation at City of Hope in late December 2016 and until now, after many contacts from my side via Tweeter and email, nobody has contacted the hospital. There are endos there who learned about Afrezza online, yes online as NOBODY ever contacted them who are asking for a presentation but Mannkind is apparently too busy to waste time with such a minute lead. This behaviour is totally explainable to me. Someone gives them a great presentation opportunity and they don't even bother to call to schedule a date in over 3 weeks. At 103 scripts per month, even 3 scripts extra is 3%... When we were dreaming about 200,000 scripts a month, this already sounds like a joke to me after 4 years invested with these guys... Just curious, but are you an employee at MannKind? It does not appear that you are. If you are not, then how can you ridicule a company for not participating in something that you arranged? In my opinion, this is ridiculous to expect to attend something an non-employee set up. It is actually entirely rude that you did not discuss this with them before you decided to do this. As an non-employee taboot. No offense, I think it is great effort on your part, but this is just ridiculous. If you discussed this with them prior, and they were originally on board, then I apologize and agree with you. But you did not say, nor incline, that you did.
|
|
|
Post by falconquest on Jan 22, 2017 5:54:58 GMT -5
CCI. You said: "I believe that Matt has many “irons in the fire” when it comes to raising cash ". You mean like his "embarrassment of riches" BS? Matt had sooo many chances to raise good cash with little dilution if he really knew what he was doing. He missed every single opportunity at doing that. Afrezza sales are dropping and Matt, Mike and their people seem totally uninterested in doing much about that. I am particularly upset as I spent quite some political capital to get them a presentation at City of Hope in late December 2016 and until now, after many contacts from my side via Tweeter and email, nobody has contacted the hospital. There are endos there who learned about Afrezza online, yes online as NOBODY ever contacted them who are asking for a presentation but Mannkind is apparently too busy to waste time with such a minute lead. This behaviour is totally explainable to me. Someone gives them a great presentation opportunity and they don't even bother to call to schedule a date in over 3 weeks. At 103 scripts per month, even 3 scripts extra is 3%... When we were dreaming about 200,000 scripts a month, this already sounds like a joke to me after 4 years invested with these guys... Just curious, but are you an employee at MannKind? It does not appear that you are. If you are not, then how can you ridicule a company for not participating in something that you arranged? In my opinion, this is ridiculous to expect to attend something an non-employee set up. It is actually entirely rude that you did not discuss this with them before you decided to do this. As an non-employee taboot. No offense, I think it is great effort on your part, but this is just ridiculous. If you discussed this with them prior, and they were originally on board, then I apologize and agree with you. But you did not say, nor incline, that you did. There are a lot of elements at play here. Without knowing all of the facts, the Endo's searched online for more info. Ceda knew someone and felt he could help facilitate a presentation, which by the way is very helpful. My initial knee jerk reaction would be to contact Mike directly but.....and this may be the issue, he has a bunch of brand new sales staff to train and get on the road. That may be his biggest priority right now (one can only hope) and so the timing may have been a factor that is impacting this situation. With all that said, it certainly wouldn't take much time for Mike to make a phone call to let a contact at the hospital know that Mannkind are eager to help them but they need a little time to get things in place. There are too many elements involved here and not enough information for any of us to draw any accurate conclusions. I certainly hope and trust that Mike will take advantage of this (and all) opportunity. That's my take.
|
|
|
Post by sportsrancho on Jan 22, 2017 9:08:58 GMT -5
Why not have one less rep and pay one person to fly all over the US giving presentations?
There were also doctors that were to give dinner talks. I'm not sure they ever happened...
I'm hoping they're swamped with all the other things they have in the works!
|
|
Deleted
Deleted Member
Posts: 0
|
Post by Deleted on Jan 22, 2017 10:03:44 GMT -5
Why not have one less rep and pay one person to fly all over the US giving presentations? There were also doctors that were to give dinner talks. I'm not sure they ever happened... I'm hoping they're swamped with all the other things they have in the works! lol.. I couldnt come up with any such things . Scheduling a presentation takes 10 min... even 4 weeks out of the day...
|
|
|
Post by saxcmann on Jan 22, 2017 10:29:38 GMT -5
Why not have one less rep and pay one person to fly all over the US giving presentations? There were also doctors that were to give dinner talks. I'm not sure they ever happened... I'm hoping they're swamped with all the other things they have in the works! lol.. I couldnt come up with any such things . Scheduling a presentation takes 10 min... even 4 weeks out of the day... Scheduling was not the problem, iam2 Maybe 2 reps less for one person to fly around, Sports. I think they are swamped with hiring and training new reps.
|
|
Deleted
Deleted Member
Posts: 0
|
Post by Deleted on Jan 22, 2017 10:37:05 GMT -5
lol.. I couldnt come up with any such things . Scheduling a presentation takes 10 min... even 4 weeks out of the day... Scheduling was not the problem, iam2 Maybe 2 reps less for one person to fly around, Sports. I think they are swamped with hiring and training new reps. you are telling me they arent even taking breaks during the day and swamped with hiring and training new reps. OK. Thanks. must be training to fly a f-35. training for Afrezza should be less than a day. let me know if you think they need more than that and if so why. city of hope is less than 60 miles from HQ. They can just drive down there and schedule a dinner meeting.
|
|
|
Post by centralcoastinvestor on Jan 22, 2017 11:23:00 GMT -5
Great write-up about MNKD's status. I just thought it missed an important point: why doctors do not actively prescribe Afrezza yet. It has been on market for two years. Most endos should already know about it, and it shouldn't be hard for endos to understand the unique PK profile of Afrezza. What is still holding them back from prescribing to at least a subset of diabetic patients? From my perspective, all of us shareholders are experiencing the amazing process of seeing how diifficult it is to change a medical paradigm. Afrezza will change how diabetes is treated. That is plainly not going to happen easily as we are all learning. I've been around so long in this stock that I had the joy of going through both Complete Response Letters (CRLs) and the FDA Advisory Committee (Adcom). It was fascinating to listen in on the Adcom. The FDA representatives who were supposed to explain how the drug worked to the panel of experts didn't have a clue how the drug even worked. It was sad. Mnkd was very fortunate to get Afrezza approved at all. In the end, doctors are just human. They get set in their ways and in many cases get insulated from the ever changing drug world. Most are overworked and frazzled. Now with Afrezza, we are asking them to unlearn the standard of care (Metformin to Combination Drugs to RRA Insulin). I believe Afrezza will change the diabetes world. How long this will take? Who knows. I think Matt and Mike are trying to inform doctors as quickly as possible. We are hamstrung by a shoestring budget. In the end, I think Mnkd and Afrezza succeeds.
|
|
|
Post by mango on Jan 23, 2017 1:31:34 GMT -5
If they truly were interested enough, wouldn't it make more sense for the Endos, themselves, to reach out to MannKind and ask to schedule a presentation? Why would they rely on someone that is not an Endo, and not even an employee? What if 10 other people randomly set up expectations with Endos about an Afrezza presentation at 10 different hospitals around the country, all without discussing it beforehand with MannKind management? If the Endos wanted one that bad, they would take the effort themselves to reach out and ask for one. That's just my opinion of the situation based on little info that was provided.
|
|
|
Post by mango on Jan 23, 2017 3:08:42 GMT -5
Scheduling was not the problem, iam2 Maybe 2 reps less for one person to fly around, Sports. I think they are swamped with hiring and training new reps. you are telling me they arent even taking breaks during the day and swamped with hiring and training new reps. OK. Thanks. must be training to fly a f-35. training for Afrezza should be less than a day. let me know if you think they need more than that and if so why.city of hope is less than 60 miles from HQ. They can just drive down there and schedule a dinner meeting. A few reasons why it would/should takw longer than 1 day to train a rep that immediately come to mind, IMO 1) Afrezza is not simply just "another insulin". It is the fastest acting insulin there is right now and behaves completely different than any of others. Fastest in, fastest out, different ROA, MOA, FDKP, inhaler 2) Afrezza consists of multiple components: Afrezza (insulin human & a monomer), new entity (FDKP), and an inhaler. 3) Afrezza has an entirely different ROA than what patients are used to. And providers. 4) Reps would need brushing up on pulmonary A&P, the MOA, aerodynamics regarding the inhaler and how the powder agglomerates etc, what makes this insulin different, why is that important, how does it benefit the body, who would benefit, why, putting it all together/actually understanding 5) Learning what FDKP is, what it does, etc 6) Reviewing literature 7) Overview of the spirometry requirement 8) Knowing everything regarding Aftezza and insurance in the territory, everything else like MannKind Cares, pt coupons, etc 9) Anything else I have left off
|
|
|
Post by promann on Jan 23, 2017 6:51:56 GMT -5
Central coast investor... Is that central east or west coast?. I enjoyed reading your analogy of site preparation and laying a good foundation but am surprised you didn't mention the footing which is the base of having a strong foundation. Anyways I totally agree and have thought the same way that MNKD is building basically a new company and script numbers though very important is not there priority till the ground work is completed. I also believe that the runway will be increased by many options so cash will not be a problem. One of which is a partner to get approvals to market and distribut Afrezza in other countries .(international partnership agreement ). MNKD already stated that they have plans to expand afrezza in several other countries in the 3Q and they also said in a earlier call that international partner was a option. Thanks for a good read
|
|
|
Post by wildthing on Jan 23, 2017 10:45:02 GMT -5
One thing I don't quite understand. Who is in the field selling afrezza while MNKD is training new reps? Is Publicis still in the picture?
|
|
|
Post by sportsrancho on Jan 23, 2017 10:52:36 GMT -5
One thing I don't quite understand. Who is in the field selling afrezza while MNKD is training new reps? Is Publicis still in the picture? Some will be kept. But they have to be trained also. At least I sure hope so!!!
|
|