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Post by kbrion77 on Jan 12, 2017 19:51:37 GMT -5
As an obsessive-compulsive grammar corrector, I would have been more impressed if they hadn't used the possessive case for the plural noun, "insulins." I would be a lot happier if they stop calling afrezza insulin except in the fine print. Insulin is viewed as a last resort in treatment. Its old, dangerous, has needles and is a crap shoot. Today he showed the technosphere slides. They need to frame afrezza as high tech nano technology which brings a new paradigm to diabetes treatment. Its not your grandma's insulin and they need to stop lumping it in with all the rest. Starbuck's doesn't sell a small coffee they sell a "tall" for x2 $ of other places, you get a grande not a medium. They need to frame afrezza as a new treatment in a class of its own. Last I checked coffee wasn't heavily regulated and scrutinized by the FDA. |
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Post by sayhey24 on Jan 12, 2017 20:01:56 GMT -5
I would be a lot happier if they stop calling afrezza insulin except in the fine print. Insulin is viewed as a last resort in treatment. Its old, dangerous, has needles and is a crap shoot. Today he showed the technosphere slides. They need to frame afrezza as high tech nano technology which brings a new paradigm to diabetes treatment. Its not your grandma's insulin and they need to stop lumping it in with all the rest. Starbuck's doesn't sell a small coffee they sell a "tall" for x2 $ of other places, you get a grande not a medium. They need to frame afrezza as a new treatment in a class of its own. Last I checked coffee wasn't heavily regulated and scrutinized by the FDA. The FDA did not tell MNKD to name the cartridges as units. That was MNKD's idea to try and make it similar to current dosing. It seemed to make sense at the time. Its been a mess. Small, medium, large or even tall, grande and venti would be better. afrezza is not a GMO insulin why are they comparing it to one. Its not a basal either. They need to spin the story and get the FDA to say - Yeah, it is different. Putting "active ingredient - insulin" in very fine print is all they need. |
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Post by nylefty on Jan 12, 2017 20:04:16 GMT -5
I would be a lot happier if they stop calling afrezza insulin except in the fine print. Insulin is viewed as a last resort in treatment. Its old, dangerous, has needles and is a crap shoot. Today he showed the technosphere slides. They need to frame afrezza as high tech nano technology which brings a new paradigm to diabetes treatment. Its not your grandma's insulin and they need to stop lumping it in with all the rest. Starbuck's doesn't sell a small coffee they sell a "tall" for x2 $ of other places, you get a grande not a medium. They need to frame afrezza as a new treatment in a class of its own. Last I checked coffee wasn't heavily regulated and scrutinized by the FDA. And Starbucks still calls coffee "coffee." |
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Post by Deleted on Jan 12, 2017 20:13:47 GMT -5
Last I checked coffee wasn't heavily regulated and scrutinized by the FDA. The FDA did not tell MNKD to name the cartridges as units. That was MNKD's idea to try and make it similar to current dosing. It seemed to make sense at the time. Its been a mess. Small, medium, large or even tall, grande and venti would be better. afrezza is not a GMO insulin why are they comparing it to one. Its not a basal either. They need to spin the story and get the FDA to say - Yeah, it is different. Putting "active ingredient - insulin" in very fine print is all they need. Wrong. Units of insulin is must to know as different people react differently to small 4 units. they need to know the equivalent insulin in it. Insulin is not cofee that you can drink some more and still be normal. |
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Post by myocat on Jan 12, 2017 20:20:35 GMT -5
Geezzzz, MNKD mgt can't spell their competitor drug right. How are they going to sell Afraiza?
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Post by sayhey24 on Jan 12, 2017 20:21:17 GMT -5
The FDA did not tell MNKD to name the cartridges as units. That was MNKD's idea to try and make it similar to current dosing. It seemed to make sense at the time. Its been a mess. Small, medium, large or even tall, grande and venti would be better. afrezza is not a GMO insulin why are they comparing it to one. Its not a basal either. They need to spin the story and get the FDA to say - Yeah, it is different. Putting "active ingredient - insulin" in very fine print is all they need. Wrong. Units of insulin is must to know as different people react differently to small 4 units. they need to know the equivalent insulin in it. Insulin is not cofee that you can drink some more and still be normal. Come on man! You have a dry powder which reacts nothing like an injectable insulin. Do you see units any where here for Exubera, they dosed in mg? www.drugs.com/dosage/exubera.html Now with afrezza you can take some more or some less. Thats the beauty. There is no carb counting. If you take too little, take another puff. Don't try that with Grandma's GMO insulin. |
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Post by Deleted on Jan 12, 2017 20:26:21 GMT -5
Do you see units any where here for Exubera, they dosed in mg? www.drugs.com/dosage/exubera.html Now with afrezza you can take some more or some less. Thats the beauty. There is no carb counting. If you take too little, take another puff. Don't try that with Grandma's GMO insulin. Wrong. diabetes.emedtv.com/exubera/exubera-dosing.htmlFor people who are switching from short-acting injectable insulin, the starting Exubera dose can be calculated based on the previous insulin dose. The 3-mg blister is approximately equal to 8 units of regular insulin, and the 1-mg blister is approximately equal to 3 units of regular insulin. It is important to note that three of the 1-mg blisters do not equal one of the 3-mg blisters.
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Post by sayhey24 on Jan 12, 2017 20:41:50 GMT -5
Do you see units any where here for Exubera, they dosed in mg? www.drugs.com/dosage/exubera.html Now with afrezza you can take some more or some less. Thats the beauty. There is no carb counting. If you take too little, take another puff. Don't try that with Grandma's GMO insulin. Wrong. diabetes.emedtv.com/exubera/exubera-dosing.htmlFor people who are switching from short-acting injectable insulin, the starting Exubera dose can be calculated based on the previous insulin dose. The 3-mg blister is approximately equal to 8 units of regular insulin, and the 1-mg blister is approximately equal to 3 units of regular insulin. It is important to note that three of the 1-mg blisters do not equal one of the 3-mg blisters.
Thats my point, they dosed in mg. MNKD did not need to call the cartridges units. That was Al's idea because Exubera dosing was hard and he thought it would make it easier. This was MNKD's marketing idea and I contend a mistake which can be corrected right now while they are asking for relabeling. To help Exubera dosing they tried to provide a conversion guide, trying to convert from units to mg. Now Eubera dosed in mg and it is your grandma's GMO insulin. afrezza is nothing like existing 6pack insulin and should not associate itself in any way with old school insulin. They need to run from the word insulin. |
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Post by mnholdem on Jan 12, 2017 21:19:42 GMT -5
Run from the word "insulin"? Respectfully, I could not disagree more. There's nothing evil about insulin. Patients with diabetes bodies are failing to produce insulin or to regulate insulin properly. What MannKind needs to do is to show how the administration and performance of OTHER insulin brands SUCK and then show how & WHY Afrezza works much so better at controlling blood sugar levels. Time-in-Zone data (i.e. CGM display data) is going to play a big part of future marketing, IMHO.
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Post by lakon on Jan 12, 2017 21:49:08 GMT -5
I would rather see them emphasize insulin by being more specific; for example, you tell the TRUTH for a change.
Afrezza is the only FDA approved inhaled insulin on the market.
Afrezza is the only NATURAL (HUMAN) rapid-acting insulin on the market. Afrezza is rapid-acting RHI so it's just like your body would make.
Afrezza is the only HUMAN INSULIN delivered in its active form.
Afrezza is the only human monomeric insulin.
Etc.
The truth will set you free.
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Post by mnholdem on Jan 12, 2017 22:01:32 GMT -5
Exactly.
The fact that it's delivered via inhalation is secondary:
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Post by sayhey24 on Jan 13, 2017 6:32:29 GMT -5
Run from the word "insulin"? Respectfully, I could not disagree more. There's nothing evil about insulin. Patients with diabetes bodies are failing to produce insulin or to regulate insulin properly. What MannKind needs to do is to show how the administration and performance of OTHER insulin brands SUCK and then show how & WHY Afrezza works much so better at controlling blood sugar levels. Time-in-Zone data (i.e. CGM display data) is going to play a big part of future marketing, IMHO. Everything you say I agree but it has not worked and trying to change the entire standard protocols is very difficult. Insulin is the last resort for T2s. When they can sell afrezza as something new and something high tech and something cool, why not? I have for a long time thought the only thing which would save afrezza would be CGM technology because the CGM does what you say. I suggested to Mike C last year his guys should be selling CGMs. Maybe thats one of the other products Matt refereed to yesterday. Maybe they can get the Dexcom guys selling afrezza. Unless Dexcom comes up with something from Google soon, Abbott and others are going to eat their lunch. |
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Post by Deleted on Jan 13, 2017 7:04:07 GMT -5
Run from the word "insulin"? Respectfully, I could not disagree more. There's nothing evil about insulin. Patients with diabetes bodies are failing to produce insulin or to regulate insulin properly. What MannKind needs to do is to show how the administration and performance of OTHER insulin brands SUCK and then show how & WHY Afrezza works much so better at controlling blood sugar levels. Time-in-Zone data (i.e. CGM display data) is going to play a big part of future marketing, IMHO. Everything you say I agree but it has not worked and trying to change the entire standard protocols is very difficult. Insulin is the last resort for T2s. When they can sell afrezza as something new and something high tech and something cool, why not? I have for a long time thought the only thing which would save afrezza would be CGM technology because the CGM does what you say. I suggested to Mike C last year his guys should be selling CGMs. Maybe thats one of the other products Matt refereed to yesterday. Maybe they can get the Dexcom guys selling afrezza. Unless Dexcom comes up with something from Google soon, Abbott and others are going to eat their lunch. Unsubstantiated rumor I heard was the Dexcom may have a force reduction and some strategy change due to Abbot's Libre being sold in the US. The US Libre requires patient to see doc every 2 weeks as their product does not provide continuous readout. With Libre you wave a receive over the CGM that is affixed on the patient's body to record the data. In Europe, patient owns the receiver and can do this themselves. In the US, the doc has a special receiver that can record the data for multiple patients. Castagna also mentioned during the last Q that he would like to have another diabetes product in his salesforce bag. |
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Post by dh4mizzou on Jan 13, 2017 7:58:33 GMT -5
Last I checked coffee wasn't heavily regulated and scrutinized by the FDA. The FDA did not tell MNKD to name the cartridges as units. That was MNKD's idea to try and make it similar to current dosing. It seemed to make sense at the time. Its been a mess. Small, medium, large or even tall, grande and venti would be better. afrezza is not a GMO insulin why are they comparing it to one. Its not a basal either. They need to spin the story and get the FDA to say - Yeah, it is different. Putting "active ingredient - insulin" in very fine print is all they need.
Just wondering. COULD they move towards identifying cartridges by the number of carbs it will negate? Eating a bagel and cream cheese use a 30 carb cartridge. Maybe that's a little to out there?
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Post by vestful on Jan 13, 2017 8:10:17 GMT -5
Unfortunately that probably wouldn't work. Early adopters have shown that the amount needed varies by the individual as well as the carbs. No two individuals seem to react the same.
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