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Post by sportsrancho on Mar 21, 2019 9:40:22 GMT -5
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Post by sportsrancho on Mar 23, 2019 18:05:48 GMT -5
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Post by uvula on Mar 23, 2019 20:23:27 GMT -5
The city of hope paper is poorly written and the study is crap.
"The simple blood test has grown in popularity because it doesn’t require patients to fast, unlike the two other most common diabetes tests."
What the heck are they talking about. The hba1c test is supposed to be a fasting blood glucose test. Of course they get bad results if people aren't fasting. The only time you do a nonfasting a1c test if if the patient forgets to fast and everyone knows the results are crap but better than nothing.
The paper also says there are 3 common tests but never says what the third test is.
Update: I'm an idiot. I was thinking of the FBG test. There are charts that show what A1c corresponds to the FBG result. But the FBG test is not actually an a1c test.
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Post by mytakeonit on Mar 23, 2019 22:48:02 GMT -5
Maybe it is actually a turd test? Ha! Or, take your pick from the list ... hemoglobin A1C, glycated hemoglobin test, glycohemoglobin, blycoslated hemoglobin, oral glucose tolerance test, etc.
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Post by babaoriley on Mar 24, 2019 0:32:38 GMT -5
The city of hope paper is poorly written and the study is crap. "The simple blood test has grown in popularity because it doesn’t require patients to fast, unlike the two other most common diabetes tests." What the heck are they talking about. The hba1c test is supposed to be a fasting blood glucose test. Of course they get bad results if people aren't fasting. The only time you do a nonfasting a1c test if if the patient forgets to fast and everyone knows the results are crap but better than nothing. The paper also says there are 3 common tests but never says what the third test is. Before you go calling the study by a fairly prestigious medical institution crap, perhaps you ought to check if fasting is required for accurate results before an hba1c test - it measures the average blood sugar over two or three months, so it seems to be what you ate a few minutes before the test doesn't mean much.
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Post by mango on Mar 24, 2019 1:56:27 GMT -5
I never have really been a fan of A1C...
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Post by liane on Mar 24, 2019 5:08:09 GMT -5
A1C test does not need to be fasting. It measures the percentage of hemoglobin that has glucose attached - and this happens over time (months). It has nothing to do with the free glucose in the blood - which can rise and fall depending on recent meals.
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Post by uvula on Mar 24, 2019 7:30:52 GMT -5
I posted a message attacking the city of hope article that other people quoted so I can't make it disappear completely. I'm an idiot. I was thinking of the FBG test. There are charts that show what A1c corresponds to the FBG result. But the FBG test is not actually an a1c test.
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Post by sportsrancho on Mar 24, 2019 7:37:29 GMT -5
It’s ok:-)
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Post by sayhey24 on Mar 24, 2019 8:24:51 GMT -5
I posted a message attacking the city of hope article that other people quoted so I can't make it disappear completely. I'm an idiot. I was thinking of the FBG test. There are charts that show what A1c corresponds to the FBG result. But the FBG test is not actually an a1c test. What the CoH study highlights is exactly what we are starting to see with more wide spread use of the Libre.
Someone I am working with started with the Libre about a month ago. He has lost his robust first phase release but still has good beta cell function and gets back to baseline in a couple of hours. However, give him a bowl of ice cream and his BG shoots well over 200+. You will never see this with an A1c test nor morning FBG test.
His family history is both his brother and mom are PWDs. The mom is an uncontrolled T2 who needs to be on insulin but won't do the shots. She knows it will make her blind - sad but true, she knows this as truth.
He asked me what he should do. The simple answer is don't eat the ice cream. He went on a keto diet and got kidney stones which is pretty usual. I gave him the best book out there on what PWDs should eat and not eat and told him to memorize pages 8-13, take a walk and lose a few pounds.
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Post by uvula on Mar 24, 2019 13:24:10 GMT -5
So does mean you could be a t2d even if the FBG is good? Does it also mean the charts correlating FBG to a1c are too simplistic and misleading?
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Post by sportsrancho on Mar 24, 2019 13:41:24 GMT -5
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Post by sayhey24 on Mar 24, 2019 15:55:06 GMT -5
So does mean you could be a t2d even if the FBG is good? Does it also mean the charts correlating FBG to a1c are too simplistic and misleading? Diabetes is on a spectrum. In reality there is no T1, T2, or most of the other terms. It all comes down to how much insulin is being made for that indivuals needs.
Most fat, lazy people do not have diabetes. Why? Their bodies make enough insulin. Their body's adapt. In fact they grow extra beta cells to make the extra insulin needed by their bodies.
What happens (if you believe Joslin's research) is a virus attacks and kills off beta cells. They have already identified certain viruses and there may be more. Once the virus hits then its up to the immune system and how well it can fight off the attack.
What we see in T1s is almost complete destruction of the beta cells, more or less depending on the PWD. With all T1s and T2s we see the initial robust release of insulin at mealtime. Thats what I described above. He has some loss but still has a lot of function. Could he have another viral attack, sure. Could he be under attack now, yes. Could he then loose his good 2nd phase action, yep.
Could a person like this be helped by afrezza? I would say this is the perfect candidate to use afrezza to supplement those times when they eat food which spikes them 160+. Of course this assumes they are using a CGM and watching the BG numbers. The alternative is to change diet and not eat those foods. Doing both and staying under 140 will probably allow beta cell regeneration assuming his immune system fights o the attack.
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Post by mytakeonit on Mar 24, 2019 17:46:25 GMT -5
A1C test does not need to be fasting. It measures the percentage of hemoglobin that has glucose attached - and this happens over time (months). It has nothing to do with the free glucose in the blood - which can rise and fall depending on recent meals. liane please tell the VA that because they always have me do a 12 hour fast. And they call it fasting ... but, time goes very slow during this 12 hours. So, they should call it slowing.
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Post by mnholdem on Mar 25, 2019 14:42:37 GMT -5
So does mean you could be a t2d even if the FBG is good? Does it also mean the charts correlating FBG to a1c are too simplistic and misleading? Diabetes is on a spectrum. In reality there is no T1, T2, or most of the other terms. It all comes down to how much insulin is being made for that indivuals needs.
Most fat, lazy people do not have diabetes. Why? Their bodies make enough insulin. Their body's adapt. In fact they grow extra beta cells to make the extra insulin needed by their bodies.
What happens (if you believe Joslin's research) is a virus attacks and kills off beta cells. They have already identified certain viruses and there may be more. Once the virus hits then its up to the immune system and how well it can fight off the attack.
What we see in T1s is almost complete destruction of the beta cells, more or less depending on the PWD. With all T1s and T2s we see the initial robust release of insulin at mealtime. Thats what I described above. He has some loss but still has a lot of function. Could he have another viral attack, sure. Could he be under attack now, yes. Could he then loose his good 2nd phase action, yep.
Could a person like this be helped by afrezza? I would say this is the perfect candidate to use afrezza to supplement those times when they eat food which spikes them 160+. Of course this assumes they are using a CGM and watching the BG numbers. The alternative is to change diet and not eat those foods. Doing both and staying under 140 will probably allow beta cell regeneration assuming his immune system fights o the attack.
High glucose levels can lead to glocuse toxicity, which also kills beta cells. See Blood Sugar 101 in the Resources section. mnkd.proboards.com/thread/3407/blood-sugar-101-tell-diabetes
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