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Post by mango on Mar 25, 2019 15:19:06 GMT -5
So does mean you could be a t2d even if the FBG is good? Does it also mean the charts correlating FBG to a1c are too simplistic and misleading? Diabetes is on a spectrum. In reality there is no T1, T2, or most of the other terms. It all comes down to how much insulin is being made for that indivuals needs. Most fat, lazy people do not have diabetes. Why? Their bodies make enough insulin. Their body's adapt. In fact they grow extra beta cells to make the extra insulin needed by their bodies. What happens (if you believe Joslin's research) is a virus attacks and kills off beta cells. They have already identified certain viruses and there may be more. Once the virus hits then its up to the immune system and how well it can fight off the attack. What we see in T1s is almost complete destruction of the beta cells, more or less depending on the PWD. With all T1s and T2s we see the initial robust release of insulin at mealtime. Thats what I described above. He has some loss but still has a lot of function. Could he have another viral attack, sure. Could he be under attack now, yes. Could he then loose his good 2nd phase action, yep.
Could a person like this be helped by afrezza? I would say this is the perfect candidate to use afrezza to supplement those times when they eat food which spikes them 160+. Of course this assumes they are using a CGM and watching the BG numbers. The alternative is to change diet and not eat those foods. Doing both and staying under 140 will probably allow beta cell regeneration assuming his immune system fights o the attack.
The second-phase is dependent on the first-phase, and so if the first-phase is diminished then the second-phase would be adversely affected and thus would be deficient.
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Post by sportsrancho on Mar 27, 2019 10:49:46 GMT -5
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Post by sportsrancho on Mar 27, 2019 17:43:26 GMT -5
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Post by sportsrancho on Mar 28, 2019 14:09:30 GMT -5
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Post by sportsrancho on Mar 28, 2019 15:15:28 GMT -5
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Post by cedafuntennis on Mar 29, 2019 6:55:57 GMT -5
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Post by sportsrancho on Mar 29, 2019 11:34:02 GMT -5
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Post by sportsrancho on Mar 29, 2019 11:35:05 GMT -5
A reminder to vote for Bill/Vdex for Board of Directors!
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Post by sportsrancho on Mar 29, 2019 15:11:54 GMT -5
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Post by sportsrancho on Mar 29, 2019 15:13:10 GMT -5
ST....$MNKD Notice how VDEX engages the audience sharing diabetes articles? Mannkind can learn something from VDEX! Open social media accounts!
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Post by careful2invest on Mar 29, 2019 17:50:31 GMT -5
ST....$MNKD Notice how VDEX engages the audience sharing diabetes articles? Mannkind can learn something from VDEX! Open social media accounts! I agree Sports! Thank God for Vdex! It is shocking to me that MannKind doesn’t utilize all of the aspects of social media. With all the benefits of how many people one can reach via social media, combined with the low cost of doing so, it really doesn’t make sense NOT to have a team of social media savvy experts promoting AFREZZA all over the internet. Hopefully, they (MNKD) is putting together a social media team as I write. Like most all of us, I was disappointed with the basically flat script numbers again after the influx of the television commercials. The 6 to 8 week model (that Mike Castagna expected) of a spike in scripts after TV ads are running doesn’t seem to be panning out. If AFREZZA is going to become the “Standard of Care”, MNKD Management needs to start doing something differently. IMHO, there is no down side to using various forms of social media. Are you reading this Mike Castagna and team at MannKind? Your investors are tired of a stock price hovering under $2.00/share for what we know is a paridigm changing treatment for Diabetes. Especially those of us that owned stock in MNKD before the reverse split! GLTA LONGS!
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Post by sportsrancho on Mar 29, 2019 18:03:02 GMT -5
This is Wall Street!...your performance as a CEO is judged on your stock price, on your promises, on your transparency! It’s been 6-8weeks ... we have no answers We have no social media, we have no Mike on Twitter. And just when I thought he was going to smash the shorts ..he smashes us. Again!
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Post by cedafuntennis on Mar 29, 2019 18:41:35 GMT -5
This is Wall Street!...your performance as a CEO is judged on your stock price, on your promises, on your transparency! It’s been 6-8weeks ... we have no answers We have no social media, we have no Mike on Twitter. And just when I thought he was going to smash the shorts ..he smashes us. Again! While I'm not happy at $2 it's a lot better than at $0 where it would have been with the previous CEOs. I think we are over reacting as we don't think any shares will be sold unless the $1.6 warrants get exercised. Company is in no need of money immediately unless they are merging with another company and clean their books off all long term debts or they want to have the I dotted for the future as now they practically don't have any more authorized shares left. However I really hope they are keeping their end of the agreement with United so they get that money we desperately need. That we need to hear from management very soon.
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Post by sportsrancho on Mar 29, 2019 18:55:33 GMT -5
I understand, I just don’t want another share plus warrant fiasco again that leads to being toxic for the share price.
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Post by sportsrancho on Mar 30, 2019 15:01:47 GMT -5
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