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Post by slugworth008 on Jun 27, 2017 10:45:08 GMT -5
He said in this interview that the worst thing about Afrezza is he has gained a little weight and he has to hit the gym more often. I think that is a huge turn off for anyone wanting to start using Afrezza. Most people with diabetes already are over weight and the the way he puts it it's a weight gainer. Is there any real data that says Afrezza is a weight gainer compared to other meal time insulins ? I think he has to be more aware of what he says but over all it was a great interview and it will spread awareness. Most of the early adopters discussed losing weight. And NO there is ZERO data regarding Afrezza and weight gain. I interpreted it as a positive meaning he can eat whatever the hell he wants to, when he wants to....Just my take on it.
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Post by straightly on Jun 27, 2017 10:47:23 GMT -5
The data says you lose a little weight. Laura mentioned that once. But it does let you eat what you want and that is part of the freedom of it. He was honest about his own experience. And it's clear he loves it:-) Should he have said it? IDK .....But he'll have a lot of time to say more and have talks with people who will have their own experiences. Beyond great move on Mikes part! I agree. But I still think he has to watch what he says. Do you think he knew he was going to say he gained weight and needs to go to the gym more often or that it just slipped. I think the latter and it was un rehearsed. It could be that he is gaining weight for other reasons then from using Afrezza and he should be careful from referring it's because of Afrezza. I think he is a great spokesperson and has a great heart and a good advocate. I don't men to sound like I'm bashing Damon Dash but I do think someone should tell him to not say your gaining weight using Afrezza is all. If everything goes as it SHOULD, Afrezza SHOULD have been a blockbuster already. I actually thought his slip made this very real. Love it.
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Post by dg1111 on Jun 27, 2017 10:50:57 GMT -5
With respect to his comment about weight gain, he clearly states that he gained weight because he is able to eat more with Afrezza. Some may actually see this as a positive.
He spoke convincingly for 6 minutes about how much Afrezza improved his life. He appears passionate and clearly believes Afrezza has improved his life and wants to share his experience with other. This is the kind of voice Afrezza has needed for a while.
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Post by sellhighdrinklow on Jun 27, 2017 10:52:25 GMT -5
Not to rain on the Damon parade but he refers to A1C as "A-1" and he says Afrezza starts working in 30-minutes. Thirty minutes?! Not true! It starts working in about 5-minutes. Even Humalog starts working in less than 30-minutes unless your blood sugar is floating in the 250+ range.
If this guy is going to be a spokesperson for Mannkind and Afrezza he needs to communicate the facts! The positive is he was talking about Afrezza on a news show. The negatives....I've already expressed and they are relevant. He spouted misinformation.
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Post by straightly on Jun 27, 2017 10:54:34 GMT -5
nadathing Yes, medications affect metabolism, however, excess calories causes weight gain. If your metabolism decreases and one continues consuming the same calories as before, that equates to weight gain. If a medication causes a decrease in metabolism and one doesn't want to gain weight, decrease your food intake. If Dash has gained weight, it is because he is eating more. My own experience: I ate MUCH less, exercised a little more, but changed from 110 pounds to 160 in a year because the use of a drug. BTW, that was a good thing and exactly what the doctor ordered.
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Post by myocat on Jun 27, 2017 10:55:43 GMT -5
My daughter at first loss some weight because we afraid of incorrectly count the carbs. Once she masters it, she tends to eat more regularly with loaded carbs. Translates that to belly fat.
Before the diagnoses, the excess glucose is flush out thru urine. Now, with the insulin carries the glucose to the blood stream which inturn becomes energy. If you don't burn the energy ---- energy is stored - we call it "FAT".
Damon Dash seems to enjoy his large dose carb meals.
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Post by Deleted on Jun 27, 2017 11:00:20 GMT -5
sellhighdrinklow there is a difference between pharmacokinetics and pharmacodynamics. Dash's comment is not incorrect.
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Post by straightly on Jun 27, 2017 11:06:39 GMT -5
He said in this interview that the worst thing about Afrezza is he has gained a little weight and he has to hit the gym more often. I think that is a huge turn off for anyone wanting to start using Afrezza. Most people with diabetes already are over weight and the the way he puts it it's a weight gainer. Is there any real data that says Afrezza is a weight gainer compared to other meal time insulins ? I think he has to be more aware of what he says but over all it was a great interview and it will spread awareness. Most of the early adopters discussed losing weight. And NO there is ZERO data regarding Afrezza and weight gain. I interpreted it as a positive meaning he can eat whatever the hell he wants to, when he wants to....Just my take on it. Well put: Loving it like in Loving life more because of Afrezza is really the key. I personally do consider being able to have a piece of Pizza once in two blue moons a wonderful thing. Forgive me but I believe we have Afrezza for people AFRaid of Eating piZZA! Go Damon, gop pizza, go Afrezza.
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Post by peppy on Jun 27, 2017 11:12:41 GMT -5
@kastanes has a valid point. Anyone can write a book and make all sorts of claims. I have not read the book; he may have some good ideas. But the gold standard is a controlled study published in a peer-reviewed journal. Why insulin causes weight gain. Weight gain is a normal side effect of taking insulin. Insulin helps you manage your body sugar by assisting your cells in absorbing glucose (sugar). ... If you have diabetes, too much glucose in your bloodstream can cause weight loss, although it's mostly water weight.Dec 7, 2016
Tips for Managing Insulin-Related Weight Gain - Healthline www.healthline.com/health/diabetes/tips-for-managing-insulin-weight-gain
Certain types of insulin are more likely to lead to weight gain than others: NPH insulin causes more weight gain than Lantus, for example, and Lantus causes more weight gain than Levemir. Now let's look at ways you can prevent weight gain. First, make sure you are not consuming more calories than your body requires.Jul 28, 2008 Maintaining Weight Loss While Taking Insulin - Everyday Health www.everydayhealth.com/specialists/diabetes/getenah/qa/weight...insulin/index.aspx
www.google.com/search?site=&source=hp&q=does+insulin+make+you+gain+weight&oq=does+insulin+&gs_l=hp.1.1.35i39k1j0l9.1854.9633.0.13326.14.13.0.0.0.0.414.2143.0j7j3j0j1.11.0....0...1.1.64.hp..3.11.2136.0..0i67k1j0i20k1j0i131k1.w8z6zF78wx8
www.joslin.org/info/why_did_i_gain_weight_when_i_started_taking_insulin.html
www.mayoclinic.org/diseases-conditions/diabetes/in-depth/insulin-and-weight-gain/art-20047836 Mayo Clinic Diet Insulin and weight gain: Keep the pounds off Insulin and weight gain often go hand in hand, but weight control is possible. If you need insulin therapy, here's how to minimize — or avoid — weight gain. By Mayo Clinic Staff
Let me know how many more meta analysis and peer view anyone would tolerate. ----------------------------------------------------------------------------------------------------------------------------------- Afrezza, the phase 1
![](https://content.screencast.com/users/mpeppy/folders/Jing/media/aeb8a93e-81e1-455a-86c9-9a6819ff01e0/2016-10-22_1319.png)
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Post by Deleted on Jun 27, 2017 11:57:44 GMT -5
It is amusing to read how people blame medications for their weight gain instead of their lack of self-control when eating. Wow we agree on something
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Post by babaoriley on Jun 27, 2017 12:26:10 GMT -5
He said in this interview that the worst thing about Afrezza is he has gained a little weight and he has to hit the gym more often. I think that is a huge turn off for anyone wanting to start using Afrezza. Most people with diabetes already are over weight and the the way he puts it it's a weight gainer. Is there any real data that says Afrezza is a weight gainer compared to other meal time insulins ? I think he has to be more aware of what he says but over all it was a great interview and it will spread awareness. Most of the early adopters discussed losing weight. And NO there is ZERO data regarding Afrezza and weight gain. I interpreted it as a positive meaning he can eat whatever the hell he wants to, when he wants to....Just my take on it. Don't forget, we understand this stuff pretty well, some here, extremely well. We are not the target of those types of promos. He did a great job, and don't forget, he's not a doctor, so should not be held to the same standard. Of course, I would prefer he stay away from the weight game comment in the future, but no big deal.
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Post by Deleted on Jun 27, 2017 12:29:17 GMT -5
I thought the interview was great. I can see how some uptight investors might be rubbed the wrong way by how he speaks. Is he your typical spokesperson, no, is Afrezza your typical diabetes drug, no. I thought he was sharp.
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Post by slugworth008 on Jun 27, 2017 13:45:00 GMT -5
Most of the early adopters discussed losing weight. And NO there is ZERO data regarding Afrezza and weight gain. I interpreted it as a positive meaning he can eat whatever the hell he wants to, when he wants to....Just my take on it. Don't forget, we understand this stuff pretty well, some here, extremely well. We are not the target of those types of promos. He did a great job, and don't forget, he's not a doctor, so should not be held to the same standard. Of course, I would prefer he stay away from the weight game comment in the future, but no big deal. Agreed on all points. Probably something Mike can and should discuss with him to change his verbiage a bit. Happy Independence day to ya.
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Post by sportsrancho on Jun 27, 2017 13:52:08 GMT -5
This is the last post regarding this topic since I don't want us to hijack this thread. I am a scientist that looks at data objectively. If data validates a claim I will accept the claim as truthful. If data does not exist it is a theory at best and science fiction at worse. If Dash wants to claim Afrezza is the cause of his weight gain and not his eating habits that is his choice, however, it doesn't imply it is truthful. No he said he gained weight because he can eat what he wants. Because Afrezza will control it. That is freedom for all PWD. There is one way to lose weight. Eat less caleries or gain muscle so you burn more caleries at rest. It's simple math. He also said Afrezza is like the internet! Gamechanger And yes promann I think it just slipped out:-)
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Post by Deleted on Jun 27, 2017 13:54:09 GMT -5
It is amusing to read how people blame medications for their weight gain instead of their lack of self-control when eating. Wow we agree on something There is a first for everything.
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