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Post by sportsrancho on Jun 2, 2018 20:21:06 GMT -5
When he said it I was mesmerized, but then I thought....wow, how true that is. Knowing kids that have used shots and Afrezza. They get used to the shots, used to the pain, used to the inconvenience, they never really get used to the scar tissue on their belly though! But they keep their chin up. It’s not till you use Afrezza you think of the other way as barbaric. Dr. Kendall evidently knows what’s coming:-) After all the medical community is getting away from anything that pierces the skin.
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Post by Deleted on Jun 2, 2018 20:52:30 GMT -5
primitive, ancient, obsolete, dinosauric, torturous, annoying as all heck, antiquated, monotonous, not conducive to being compliant, etc. etc. oh yeah, forgot a big one NOT AS SAFE, less convenient, do you think those physicians would get turned off with the use of those descriptions as well?
I prefer respectful dialogue, but I'll entertain your question. Primitive, ancient, obsolete, and antiquated would all be better than "barbaric". If you look at the first definition of barbaric (found by googling "barbaric"), which is the one I think the vast majority of users intend when they say barbaric it, you would get: savagely cruel; exceedingly brutal. A graphic of needles sticking out of a child is certainly a powerful image, but as agedhippie has said in his post(s), very few insulin injections, if any, are given with a syringe instead of a very fine pen needle. There is a psychological barrier to overcome with injection, but once it's overcome, self-injection is not that big of a deal. To call it savagely cruel or brutal would be a gross overstatement, and as such, I believe it may cause lack of credibility. To put it another way, what if someone handed you mild salsa and told you it was barbaric to eat it? Some people can't even taste the spiciness of mild salsa. They would laugh at anyone who called it barbaric. If that person instead said that mild salsa had less flavor, less zest, etc, than spicier salsa, they'd be much more effective in their communication. Primitive/obsolete has a much different meaning than savagely cruel or exceedingly brutal. While you can disagree with me if you'd like, I am of the opinion that any of the other adjectives in blue would have been better suited to address the medical community as they are more objective and less reliant on sensationalism. Does using even something like a fine pen needle require rotation of injection sites? |
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Post by sportsrancho on Jun 2, 2018 21:15:19 GMT -5
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Post by gareaudan on Jun 2, 2018 21:35:31 GMT -5
wow! And some people still saying that injection is not a big deal anymore since it is less painfull. Im not diabetic but ''you may develop hardened areas under the skin that keep the insulin from being used properly'' doesnt sound right to me... |
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Post by gareaudan on Jun 2, 2018 21:40:52 GMT -5
You're right, a more accurate way of saying it and what I should have said is that the value of the shares that i bought in 2013 is over, not mnkd. If we need another product to be successful, it will take many more years and probably many more big dilutions. Mnkd will still be there but it will be hard to recover the lost in value of those shares. You realise that some people bought at 30-35$. It is x15 from now just to get even or around 6,5 b in mc... Witout anymore dilution... Ultimately, It is very Nice if mnkd survive and all but what I want is to see my money back and more. I didnt invest in mnkd in 2013 as a charity so they can survive but to make more money. That being said, i do think 10b is attainable at some point in the futur if every things goes well and thats why i also bought a lot below 2$ so im confident that overall Ill be good but still thinking about my 2013 shares. Maybe im seeing it the wrong way. Of course if you think the mc can go to 25b, 50b dilution doesnt really matter so it is a question of perspective but i think this is a bit stretching, especially if afrezza is not a success. I do sense a change in sentiment, and believe sooner than later MNKD longs will be on the right side of the trade again. again,,just my opinion Time will tell ✌🏻😎 We are on the same page here rsr 😃. Good luck with your investment strategies. |
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Post by letitride on Jun 2, 2018 21:47:27 GMT -5
If you look at the first definition of barbaric (found by googling "barbaric"), which is the one I think the vast majority of users intend when they say barbaric it, you would get:
savagely cruel; exceedingly brutal.
Damn if that does not describe my thoughts when I saw this kid on the beach and thought to my self, if he aint lucky to be alive after taking a gut full of buck shot only to learn that's the way you treat diabetes. Barbaric maybe not at the time but sure as hell looked that way. But now given a better alternative I cant think of a better way to describe it.
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Post by Deleted on Jun 2, 2018 21:56:42 GMT -5
primitive, ancient, obsolete, dinosauric, torturous, annoying as all heck, antiquated, monotonous, not conducive to being compliant, etc. etc. oh yeah, forgot a big one NOT AS SAFE, less convenient, do you think those physicians would get turned off with the use of those descriptions as well?
I prefer respectful dialogue, but I'll entertain your question. Primitive, ancient, obsolete, and antiquated would all be better than "barbaric". If you look at the first definition of barbaric (found by googling "barbaric"), which is the one I think the vast majority of users intend when they say barbaric it, you would get: savagely cruel; exceedingly brutal. A graphic of needles sticking out of a child is certainly a powerful image, but as agedhippie has said in his post(s), very few insulin injections, if any, are given with a syringe instead of a very fine pen needle. There is a psychological barrier to overcome with injection, but once it's overcome, self-injection is not that big of a deal. To call it savagely cruel or brutal would be a gross overstatement, and as such, I believe it may cause lack of credibility. To put it another way, what if someone handed you mild salsa and told you it was barbaric to eat it? Some people can't even taste the spiciness of mild salsa. They would laugh at anyone who called it barbaric. If that person instead said that mild salsa had less flavor, less zest, etc, than spicier salsa, they'd be much more effective in their communication. Primitive/obsolete has a much different meaning than savagely cruel or exceedingly brutal. While you can disagree with me if you'd like, I am of the opinion that any of the other adjectives in blue would have been better suited to address the medical community as they are more objective and less reliant on sensationalism. Familiar with site rotation as best practice. But does using fine pen needles reduce this necessity? |
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Post by dreamboatcruise on Jun 3, 2018 0:35:56 GMT -5
If you look at the first definition of barbaric (found by googling "barbaric"), which is the one I think the vast majority of users intend when they say barbaric it, you would get: savagely cruel; exceedingly brutal. Damn if that does not describe my thoughts when I saw this kid on the beach and thought to my self, if he aint lucky to be alive after taking a gut full of buck shot only to learn that's the way you treat diabetes. Barbaric maybe not at the time but sure as hell looked that way. But now given a better alternative I cant think of a better way to describe it. While that may happen for some patients, I think that is not at all the norm to have such severe injection site reactions. For many patients, and especially doctors old enough to remember older treatment options, they would likely view today's ultra long acting basals and RAAs delivered with very fine needle pens as being amazing advancements rather than barbaric. And I would just speculate that the doctors that currently are resistant to prescribing Afrezza are unlikely to be swayed to do so by someone calling their current medical practices "barbaric". Could be wrong, what do I know about psychology... maybe calling people barbaric is persuasive? I'm just thinking I wouldn't like it if I were an endo. To me, perhaps I'm over simplifying, I think a strong marketing message is that Afrezza allows one to tailor their insulin around what they eat rather than either forcing one's diet to conform to the insulin or settling with damaging and risky glucose variability. I think current injected insulins can be perfectly good solutions for those willing to learn and adjust to the needs of the insulin... which many/most don't achieve. |
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Post by pat on Jun 3, 2018 6:13:05 GMT -5
Georgethenight - is your profile picture an animated "Wooderson" from Dazed and Confused?
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Post by letitride on Jun 3, 2018 9:22:28 GMT -5
If you look at the first definition of barbaric (found by googling "barbaric"), which is the one I think the vast majority of users intend when they say barbaric it, you would get: savagely cruel; exceedingly brutal. Damn if that does not describe my thoughts when I saw this kid on the beach and thought to my self, if he aint lucky to be alive after taking a gut full of buck shot only to learn that's the way you treat diabetes. Barbaric maybe not at the time but sure as hell looked that way. But now given a better alternative I cant think of a better way to describe it. While that may happen for some patients, I think that is not at all the norm to have such severe injection site reactions. For many patients, and especially doctors old enough to remember older treatment options, they would likely view today's ultra long acting basals and RAAs delivered with very fine needle pens as being amazing advancements rather than barbaric. And I would just speculate that the doctors that currently are resistant to prescribing Afrezza are unlikely to be swayed to do so by someone calling their current medical practices "barbaric". Could be wrong, what do I know about psychology... maybe calling people barbaric is persuasive? I'm just thinking I wouldn't like it if I were an endo. To me, perhaps I'm over simplifying, I think a strong marketing message is that Afrezza allows one to tailor their insulin around what they eat rather than either forcing one's diet to conform to the insulin or settling with damaging and risky glucose variability. I think current injected insulins can be perfectly good solutions for those willing to learn and adjust to the needs of the insulin... which many/most don't achieve. Well that makes sense as long as only a few have horrible injection site reactions and the needles are smaller. NOT! |
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Post by dreamboatcruise on Jun 3, 2018 9:40:59 GMT -5
While that may happen for some patients, I think that is not at all the norm to have such severe injection site reactions. For many patients, and especially doctors old enough to remember older treatment options, they would likely view today's ultra long acting basals and RAAs delivered with very fine needle pens as being amazing advancements rather than barbaric. And I would just speculate that the doctors that currently are resistant to prescribing Afrezza are unlikely to be swayed to do so by someone calling their current medical practices "barbaric". Could be wrong, what do I know about psychology... maybe calling people barbaric is persuasive? I'm just thinking I wouldn't like it if I were an endo. To me, perhaps I'm over simplifying, I think a strong marketing message is that Afrezza allows one to tailor their insulin around what they eat rather than either forcing one's diet to conform to the insulin or settling with damaging and risky glucose variability. I think current injected insulins can be perfectly good solutions for those willing to learn and adjust to the needs of the insulin... which many/most don't achieve. Well that makes sense as long as only a few have horrible injection site reactions and the needles are smaller. NOT!Of PWD I know on insulin, I don't know any with the type of reaction described where one could see scarring of someone at the beach. But quite frankly, I'm not even sure I know what you were trying to convey with the beach story. What you are saying doesn't make sense? The needles indeed are much smaller than were used a couple of decades ago with syringes... and "horrible" injection site reactions are indeed quite rare. And just because a few people have reactions to something doesn't to me mean it is barbaric... peanuts aren't barbaric because some nearly die when they eat them. |
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Post by sportsrancho on Jun 3, 2018 10:26:03 GMT -5
If Afrezza came first would anybody be using a pen?
In my opinion the pen will become obsolete because with Afrezza there are less steps... more convenience, no pain, ( some insulin’s really sting ) no scar tissue to contend with. It works faster. You don’t have to plan out your meals. You can keep it in your car, or wherever you want for emergency corrections because it lasts for months or years without refrigeration. And it has a cool factor! Especially with the kids:-)
10 years from now people just may think pens were barbaric...
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Post by sportsrancho on Jun 3, 2018 11:37:05 GMT -5
This is incredible! I never listen to it all the way through. Sam explains dosing, CGM’s. Says no side effects, no meal planning! Afrezza is the..”Smart insulin”
All about being in the trials. His near death experience on other insulin’s. Also talks about how ridiculous or un-needed the breath test is.
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Post by mannmade on Jun 3, 2018 11:59:44 GMT -5
Btw I recall a article from a couple of years back interviewing Bill Doub, then one of the head research scientists at the FDA in charge of among other things evaluating inhalables. Bill mentioned in the artilce that he thought this was the future especially with dry powders as they seem to be the most convenient and effective. (I am paraphasing from memory) I will try to see if I can find it and post it later...
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Post by peppy on Jun 3, 2018 12:59:53 GMT -5
If Afrezza came first would anybody be using a pen? In my opinion the pen will become obsolete because with Afrezza there are less steps... more convenience, no pain, ( some insulin’s really sting ) no scar tissue to contend with. It works faster. You don’t have to plan out your meals. You can keep it in your car, or wherever you want for emergency corrections because it lasts for months or years without refrigeration. And it has a cool factor! Especially with the kids:-) 10 years from now people just may think pens were barbaric... if afrezza came first would anyone tolerate the hyperglycemia, hypoglycemia of subq rapid acting insulin? www.screencast.com/t/NJow1xn5RzPMthe poor blood glucose control of subq rapid acting insulin is the primitive part. |
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