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Post by jmkopp on Mar 26, 2018 10:28:29 GMT -5
I am astonished at the lack of partnerships over the past couple of years. I really can't believe other companies can't find the value in Afrezza and/or the potential of partnering on a drug for Technosphere.
Is it more likely that MNKD is :
1. Trying to create success with Afrezza first to justify that other Technosphere drugs can be successful 2. No upfront cash offered from potential partners makes MNKD wait for other deals 3. The deals they are being offered are low ball offers 4. Other companies hoping MNKD goes bankrupt to bid on techology 5. No one is interested
The lack of Technosphere partners is staggering in that there is so much opportunity. Companies with eligible drugs for Technosphere that are running out of IP can create a new form of their drug that will probably be way more efficient on Technosphere and also adds a substantial amount of years to their IP on the drug. I just can't understand the apparent lack of interest.
On a side note. I was heartened a little in a call I put into Dr. Richard Bernstein in January. He is the father of the low carb diet strategy for PWD and was one of the first to try to measure his blood sugar many times throughout the day with a cgm. I asked him his thoughts on Afrezza and he responded by saying, they (meaning his clinic) will be trying it out next month. If that is the case he has probably seen Afrezza in action for about a month. Hopefully he will see the same amazing results we have all witnessed. I believe he would be another great advocate for Afrezza moving forward.
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Post by nadathing on Mar 26, 2018 10:48:34 GMT -5
I was certain our fortune was twofold. Afrezza being a success and BP lining up for TS partnerships. I can’t believe how wrong I was. I hold no hope for the prospect of paying TS partnerships going forward. I am no longer of the belief that Afrezza will be successful in this he adult diabetes population. I hold in the belief that the market is Juvenile T1’s. Kids embrace technology. Combine Afrezza with a CGM with blue tooth and they will figure out how to titrate it successfully.
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Post by digger on Mar 26, 2018 11:09:16 GMT -5
Where is Bernstein's clinic? At 83, I figured he'd be retired by now.
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Post by sportsrancho on Mar 26, 2018 11:12:34 GMT -5
Brendan, “I am being contacted on social media by folk living in the USA who have never heard of #Afrezza I can't believe this is still happening. 😠 It will come good in the end. Admittedly i was heavily motivated to do my research on #Afrezza when current therapies failed me. Most people don't take this approach and need some1 with a white coat 2save them. I may not agree with this strategy but i understand why this is so.”
Agree the kids will lead the way. Plus parents are much more motivated to demand it from the Endo’s for their kids than they are themselves.
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Post by boca1girl on Mar 26, 2018 11:46:18 GMT -5
I was certain our fortune was twofold. Afrezza being a success and BP lining up for TS partnerships. I can’t believe how wrong I was. I hold no hope for the prospect of paying TS partnerships going forward. I am no longer of the belief that Afrezza will be successful in this he adult diabetes population. I hold in the belief that the market is Juvenile T1’s. Kids embrace technology. Combine Afrezza with a CGM with blue tooth and they will figure out how to titrate it successfully. I agree with your statement about the kids. I am also disappointed in the lack of TS partnerships a slow uptake in adults, but I have NOT lost all hope as you have. It has just taken much longer to turn the big “battle ship” than I, or most here had expected.
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Post by lojothehus on Mar 26, 2018 12:48:35 GMT -5
Whenever Babe Ruth went up to bat, he would point to the area where he'd hit his homerun. Whenever Mike Tyson stepped in the ring, someone was going to get knocked out. Whenever Michael Jordan stepped into the arena, his opponents already knew what he planned to do to them. Muhammad Ali, would use every vowel in his vocabulary to his advantage.
Greatness always precedes itself. You'd better believe that everyone in those stadiums, or arenas, knew what each and every one of those men could do. However, as great as these men were; they relied on more than their greatness in their paths to success. They made noise, they created a stir, in a form of uniqueness they let the world know what they could do.
Afrezza will and can be successful, but Mankind needs to create a stir.....they need to introduce Afrezza's GREATNESS! It's one thing to prove its superiority in the medical world, but it only becomes great when the "common man" gets to hear about it! Sound the trumpets Mankind; yell from everywhere; don't fear the giants...defeat them! It's time to create an Afrezza movement!
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Post by jmkopp on Mar 26, 2018 12:49:35 GMT -5
Where is Bernstein's clinic? At 83, I figured he'd be retired by now. I believe he still works with patients in Mamaroneck, New York.
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Post by mnholdem on Mar 26, 2018 14:31:40 GMT -5
Retirement isn't always what it's cracked up to be for some people. The only post-retirement plan I've made so far is to attend my funeral. ;-)
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Post by brotherm1 on Mar 26, 2018 14:31:49 GMT -5
Where is Bernstein's clinic? At 83, I figured he'd be retired by now. For those sincerely interested, a quick Google search brings him right up at the top of results: Richard K. Bernstein (born June 17, 1934) is a physician and an advocate for a low-carbohydrate diabetes diet to help achieve normal blood sugars for diabetics. Bernstein has type 1 diabetes. His private medical practice in Mamaroneck, New York is devoted solely to treating diabetes and prediabetes. He is a fellow of the American College of Nutrition, the American College of Endocrinology and The College of Certified Wound Specialists. He is the author of six books on diabetes and normalizing blood sugars. en.m.wikipedia.org/wiki/Richard_K._Bernstein
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Post by brotherm1 on Mar 26, 2018 14:38:13 GMT -5
Retirement isn't always what it's cracked up to be for some people. The only post-retirement plan I've made so far is to attend my funeral. ;-) Just remember what Yogi Berra said. “If you don’t attend other people’s funerals, they won’t attend yours.”
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Post by falconquest on Mar 26, 2018 19:20:29 GMT -5
The lack of Technosphere partnerships has been the big disappointment of Mannkind in my opinion. It's almost like Big Pharma has a gentlemen's agreement amongst themselves that they will not allow this technology to become successful. In my head I want to believe that Al Mann was far brighter than BP will accept. He stepped out of the norm and created a delivery system that skunked everyone and they're intent on not allowing it to be successful. Think Tesla. I don't know that this is the case but it's what I really want to believe. Hakan and Matt believed but the Pharma realm didn't and wouldn't allow it to be a success. That's why I got out. I seriously believe in this drug and the delivery platform, I just don't believe to this point it will be allowed to succeed. Hate to say it but them's the facts as I see it folks.
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Post by brotherm1 on Mar 26, 2018 19:53:03 GMT -5
OK there Falcon. It’s been real. You take good care now. Perhaps we’ll see you sometime on a board about another stock. Take care now. ✋
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Post by digger on Mar 26, 2018 20:17:40 GMT -5
Where is Bernstein's clinic? At 83, I figured he'd be retired by now. I believe he still works with patients in Mamaroneck, New York. When I googled for his clinic,, it gave the gave, "New York Diabetes Center 1160 Greacen Point Rd Mamaroneck, NY 10543." But when I google mapped that , it turns out to be a nice house -- an appraised at 3 million dollar nice house -- in a ritzy community. I would doubt that he sees patients there.
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Post by nylefty on Mar 26, 2018 21:57:25 GMT -5
I believe he still works with patients in Mamaroneck, New York. When I googled for his clinic,, it gave the gave, "New York Diabetes Center 1160 Greacen Point Rd Mamaroneck, NY 10543." But when I google mapped that , it turns out to be a nice house -- an appraised at 3 million dollar nice house -- in a ritzy community. I would doubt that he sees patients there. I also GoogleMapped that address and on the map at that location it says "Diabetes Center."
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Post by #NoMoreNeedles on Mar 27, 2018 3:22:07 GMT -5
Yeah, Hakan and Pfeffer did a wonderful job! Mike has to rebuild everything from scratch, it will take 2 years for MannKind to become major pharma player.
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