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Post by mnholdem on May 17, 2018 7:30:18 GMT -5
From link provided by digger (above):
CONCLUSION
Assessing only the cost of treatment by direct cost analysis performed in this study, it was possible to conclude that Regular insulin and NPH were the best options for the treatment of DM. Still considering direct cost analysis, the insulins aspart and detemir were alternatives as the best choice among the insulin analog options, and aspart presented no possibilities of being more costly than the other fast-acting insulin options evaluated. According to sensitivity analysis, the best options among the insulin analogs were detemir and aspart. However, the insulin detemir was a dominated option according to uncertainty scenarios. Thus, our study showed there was evidence for aspart to be the most cost-effective insulin option when targeting an increment in reducing HbA1c and possible improvement in glycemic control.
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The study compared, among other factors, the cost of analog/regular/NPH insulin with it's effectiveness at reducing A1c, using a formula that resulted in aspart being the most cost-effective. However, Afrezza Inhaled Insulin (human) was not included in the study. Once the science behind Technosphere Insulin becomes common knowledge, I'm certain that Afrezza will take that top spot away from aspart, as the STAT study may soon confirm.
MannKind CMO David Kendall MD will probably work with international partners Biomm (Brazil) and Cipla (India) to communicate the significant medical and cost advantages of Afrezza over the other analog/regular insulin brands, especially compared to aspart, the current #1 prandial insulin analog.
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Post by goyocafe on May 17, 2018 7:44:37 GMT -5
What happened to the list of questions the members of this board helped compile for the ASM?
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Post by uvula on May 17, 2018 8:02:52 GMT -5
Mike talked about scripts rising & said he is not interested in seeing scripts go from 500 to 550 a week. He wants to see scripts go from 500 to 5000 a week! He mentioned 5000 scripts a week a couple of times today. Great mtg overall but I didn't like some of the "pandering to the audience" comments that sound nice but are meaningless. |
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Post by mango on May 17, 2018 8:04:14 GMT -5
I got to thinking about the man with T1D that died last year in jail from being deprived of medical care (insulin) for like 3 days.So I thought about how bad it probably is for all PWD that are incarcerated and wondered what the numbers were. I found something from 2012 by the ADA that estimated 4.8% of the prison population in the US had diabetes. I bet it is currently close to 8-10%, what do ya'll think? I asked MannKind what they thought about it too. MannKind already made plans to target this population sometime in the future. Thought that was really cool.
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Post by uvula on May 17, 2018 8:09:45 GMT -5
Mango, that is cool. A group of people that shouldn't have access to needles and syringes.
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Post by hellodolly on May 17, 2018 8:11:41 GMT -5
I got to thinking about the man with T1D that died last year in jail from being deprived of medical care (insulin) for like 3 days.So I thought about how bad it probably is for all PWD that are incarcerated and wondered what the numbers were. I found something from 2012 by the ADA that estimated 4.8% of the prison population in the US had diabetes. I bet it is currently close to 8-10%, what do ya'll think? I asked MannKind what they thought about it too. MannKind already made plans to target this population sometime in the future. Thought that was really cool. Working in corrections now, I know the hurdle will be the dreamboat being introduced into the prison population. Lord knows what else they'll try and 'smoke' or 'inhale' with it besides Afrezza? Can the prison infirmaries keep those locked up and account for them? Probably, but with some trepidation. Needles are 'one and done' and pills are even better in these environments. My boss always tells me that this is the biggest hospital n the county. BS! It's the biggest glorified clinic in the county. I tell my inmates during their orientation, "Do NOT get sick in here." |
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Post by peppy on May 17, 2018 8:15:31 GMT -5
I am waiting for sports sunshine/ and other attendees to wake up.
Good day sunshine.
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Post by MnkdWASmyRtrmntPlan on May 17, 2018 9:13:44 GMT -5
1. Concern about meeting revenue forcast? 2. Why do refills appear low? 3. How do we go back and get the people who tried Afrezza and stopped? 4. How do we spread the word about Afrezza? Anyone remember the answers to these questions? |
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Post by uvula on May 17, 2018 9:20:49 GMT -5
1. Concern about meeting revenue forcast? 2. Why do refills appear low? 3. How do we go back and get the people who tried Afrezza and stopped? 4. How do we spread the word about Afrezza? Anyone remember the answers to these questions? 1. We will meet forcast with small % month over month increase. Not concerned. 2. Mike deflected with his " I'm not interested in going from 500 to 550. I want to go from 500 to 5000". (Not an exact quote) 3. We will contact people who contacted us for info on afrezza . It wasn't clear to me if they have access to the identities of past users who stopped using. 4. Publish publish publish. |
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Post by mango on May 17, 2018 10:11:50 GMT -5
Mango, that is cool. A group of people that shouldn't have access to needles and syringes. Hmm. My best friend is a veteran and participated in a war, both him and his dad together in Apaches to keep these prisons up and running. Then spent two years in one for being addicted to heroin. That war wasn't justified but at least there are people willing and wanting to lay their life down for others. Anyways, he developed PTSD and depression from that became an addict. This country has suffered from an opium addiction since the 1800's. Those people that smoked in the opium dens around California were never thrown in prison for it. Instead, Cannabis was made illegal and addiction was regulated and tolerated. Al Mann helped drop an atomic bomb on people, does that mean he is less than yourself? He spent his entire life to help others, and I imagine that war had a lot to do with shaping his life. That's why no one needs to be playing judge. Al Mann laid his life down for others in an effort to save a lot of people. The past can't define you, it's what you believe in that does. I'm sorry but damn I just simply do not understand that thinking. I would want any person in any prison to have access to a needle and syringe if the needed it. Why judge and assume "they" cannot be trusted? I am sure you cannot be trusted with something, I know I can't be trusted to keep my mouth shut. Amazing people make mistakes and end up in that hell hole. The ones that want to keep them open are the ones I would worry about trusting, after all it was the jail administrator that deliberately killed the dude with T1D. |
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Post by uvula on May 17, 2018 10:27:20 GMT -5
Whoa mango, I'm not sure how my comment resulted in your post.
Insulin syringes could be used for injecting other bad things. A dreamboat cannot be abused this way. Eliminating syringes in the prison would be a good thing. In fact eliminating all pointy objects would be good.
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Post by hellodolly on May 17, 2018 10:28:40 GMT -5
Mango, that is cool. A group of people that shouldn't have access to needles and syringes. They don't have that access. The meds and the equipment are all maintained in the infirmaries. No inmate has a needle...or, they shouldn't have access. Nurses make their rounds to the cells each day and administer the daily meds, as prescribed by the doctor after a careful medical screening. It would be cool if the nurses could some how be available in the dining halls to administer a dose of Afrezza, each meal. All they have to do is look at the inmate wristband to confirm their ID and see if they are on the list of approved inmates and the dose amount. FWIW |
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Post by akemp3000 on May 17, 2018 10:48:25 GMT -5
Seems time to close a thread regarding "Notice of Annual Stockholders Meeting". Results of the meeting are in another thread.
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Post by sportsrancho on May 17, 2018 11:01:41 GMT -5
I am waiting for sports sunshine/ and other attendees to wake up. Good day sunshine. Thanks Peppy, love you! I just woke up I was so exhausted. One thing I remember is that when someone goes to order a prescription and gets three months it’s counted as one refill not three. Tom stood up in the meeting and asked several good questions, that was one of the answers. Little piece of trivia: Mike reached over in between his two fingers and held Beazer’s paw while he was talking to someone else. Beazer usually scared of everyone kissed his fingers:-)) |
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Post by liane on May 17, 2018 11:03:17 GMT -5
Beazer is a good judge of character!!!
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