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Post by compound26 on Jul 2, 2015 18:06:26 GMT -5
Can we have Tom Hanks starring the ad? www.nydailynews.com/entertainment/tv-movies/tom-hanks-reveals-diabetes-diagnosis-article-1.1479293Tom Hanks joked about having Type 2 diabetes in an interview with David Letterman on 'Late Show.' Tom Hanks might be an award-winning movie star, but he still needs to watch his health. The "Captain Phillips" star stopped by David Letterman's "Late Show" to chat about his new flick, but also revealed that he has been diagnosed with Type 2 diabetes. Explaining his recent weight loss to the talk show host, Hanks, 57, said his doctor told him, "You've graduated. You've got Type 2 diabetes, young man."The two-time Oscar winning actor said he'd been struggling with high blood sugar since he was 36 years old and that his condition is "controllable.""Something's going to kill us all, Dave," Hanks joked. He isn't the first big name to be linked to the common blood sugar disease. Sherri Shepherd, Biz Markie, Paula Deen and Drew Carey are among the notable celebrities who have revealed their battles with Type 2 diabetes. Nick Jonas, the youngest of the Jonas Brothers trio, has advocated for more research on the disease, frequently speaking out about his fight with Type 1 diabetes. The "Forrest Gump" star explained to Letterman that his doctor advised he should weigh as much as he weighed in high school in order to attain complete health. "And I said to her, 'Well I'm gonna have Type 2 diabetes,'" Hanks joked. “There was no way I was gonna weigh what I weighed in high school. ... I was 96 pounds.”
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Post by compound26 on Jul 2, 2015 14:59:34 GMT -5
It took me 6 weeks to see my endocrinologist for the initial 45 minute first appointment allotment slot. Less than one week to have IOS Spirometry test scheduled and one more week to see endocrinologist to evaluate test results. Two sample kits of Afrezza obtained that carry me another 20 days. From what I'm hearing, this is a typical timeline, if not slower than mine since my schedule fit the endocrinologist's or visa versa. I will not have my first script written until I see him again with my logbook on June 1st. The whole process from the initial endo phone call to Afrezza written script takes roughly 3-4 months. Now you can see why it's taking so long to build up script numbers (Nrx) and refills (Rrx)!! It hasn't even been 4 months since official launch date.
BTW, I am a T2 Afrezza user like my friend Spiro. It appears Brian's experience is in line with what was described in the following article. This also supports Matt's remark that the current scripts numbers is about 8 weeks behind the demand curve. Endocrine shortage -Shortfall in number of US endocrinologists www.bariatricnews.net/?q=news/111524/shortfall-number-us-endocrinologistsA growing shortage of endocrinologists could force patients to wait longer to see a doctor, according to a Endocrine Society workforce analysis published in the Journal of Clinical Endocrinology & Metabolism. The analysis found there is currently a shortage of about 1,500 adult and 100 paediatric full-time endocrinologists in the US. The demand for paediatric endocrinologists is expected to be met by 2016 as the workforce grows. The gap between supply and demand for adult endocrinologists, however, is expected to remain the same or grow worse as more people are diagnosed with endocrine conditions. This could lead to longer wait times for patients seeking appointments. The Society's survey found the average wait time for adults making a non-urgent appointment with an endocrinologist was 37 days in 2012. The average wait remained unchanged from 1999, despite a 52 percent increase in the number of board-certified endocrinologists serving adults.
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Post by compound26 on Jul 2, 2015 8:39:42 GMT -5
newmnkdinvestor, I am sure Sanofi will promote Afrezza to many different potential user groups but starting with seniors is a very good idea since seniors make up the largest portion of the T2 diabetic community. They account for over 25% of all diabetics and they are very poorly administered with injection insulin therapy. Doctors allow them to remain with unhealthy A1C levels over 8 before starting night time injection. But, with Afrezza, the elderly can start with a meal time insulin, Afrezza, which will help to lower their A1C, without the same level of hypoglycemic risk associated with injections. Please take a look at an article I wrote on the subject. It should answer some of your questions: seekingalpha.com/article/3201286-mannkinds-afrezza-inhaled-insulin-a-game-changer-for-seniors-with-diabetes?auth_param=2hisp:1alqr2c:77d42ea8b2b1f626a13cdc0fb5447fa6&uprof=44Best wishes, RS Agree. Here is what the author of "The Failure of Exubera: Are We Beating a Dead Horse?" has to say about this issue: www.ncbi.nlm.nih.gov/pmc/articles/PMC2769732/As mentioned before, elderly patients might also represent a huge group of patients that are interested in an easy-to-use inhaler that requires no dialing of the insulin dose on an insulin pen or complex handling of an inhaler. For many of these patients, optimal metabolic control is the therapeutic target but application of at least some insulin with each meal would help keep their postprandial glycemic excursions in an acceptable range. We should also not ignore the fact that in many countries of the world beside the United States and Europe selfadministration of a substance/drug is disliked by patients because of cultural/religious reasons. For such patients, and their number is increasing rapidly, the possibility of inhaling a drug is a very attractive option. It might very well be that the big pharmaceutical companies of the western hemisphere, which are very much focused on the classical markets, will be surprised by the rapidity and consequence with which pharmaceutical companies in China or India will come along with developments specifically developed for their own countries, which do represent huge markets.
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Post by compound26 on Jun 26, 2015 15:02:04 GMT -5
Did a quick search on the website traffic of Afrezza.com on Compete.com. The result is attached. If the data presented there are reliable, it appears the website traffic increased substantially in May 2015 over April 2015 (from 3,116 visitors to 22,519 visitors). The June 2015 data are not available yet. The previous peak was 9,689 visitors in Feb 2015. Attachment Deleted
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Post by compound26 on Jun 25, 2015 10:50:00 GMT -5
Wow, pretty impressive. I like the videos. Thanks, harry.
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Post by compound26 on Jun 18, 2015 0:38:55 GMT -5
"Oscar, just curious, are you long or short on MNKD? If you do not mind, could you disclose that?"
I have zero financial interest in MNKD stock or in any derivative thereof.
Thanks, Oscar.
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Post by compound26 on Jun 18, 2015 0:04:18 GMT -5
Oscar, just curious, are you long or short on MNKD? If you do not mind, could you disclose that?
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Post by compound26 on Jun 16, 2015 4:11:24 GMT -5
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Post by compound26 on Jun 8, 2015 11:59:33 GMT -5
LOL, each Motley Fool article always ends with something like this "As a result, investors with an eye on the long-term may want to stick to the sidelines with this volatile biotech -- at least until Afrezza is showing clear signs of living up to its blockbuster potential". No matter what the price of a particular stock is (or was). In that way, the author can claim that he never makes any mistake because he did not take any position (one way or the other).
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Post by compound26 on Jun 7, 2015 16:07:55 GMT -5
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Post by compound26 on Jun 6, 2015 17:42:27 GMT -5
I was looking at $7 Jan. you can write the puts and buy the calls for $2.64 credit, synthetic long position equivalent to getting shares for $3.48. That's crazy, and is indicative that options are pointing to this going lower again. Ugh. fugacity, do you mean getting the shares at $4.36=($7-$2.64)?
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Post by compound26 on Jun 6, 2015 13:34:43 GMT -5
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Post by compound26 on Jun 6, 2015 4:08:15 GMT -5
There is some interesting discussion regarding this report on Tudiagetes.org. www.tudiabetes.org/forum/t/i-started-on-afrezza-last-night/23316/222crg Very cool news! The Los Angeles Times interviewed and photographed me for an article about Afrezza, and the article appeared on the front page of the Business section this Wednesday, June 3. 15 Sam19 Read that article even before I realized that was you. Very cool. I think the point that needs to be emphasized because even doctors don't understand it, is that this not just an alternative to needles... It works far better for many people. That's what frustrates me.... I've stuck myself with needles countless times every day, it really doesn't bother me or most other people who've done the same... But this med is giving me my life back. crg It's true. It's not insulin in a different form. It's a completely different product. That is hard to get people to understand. It was hard for me to believe at first, too. karen57 Quoting crg: It's true. It's not insulin in a different form. It's a completely different product. That is hard to get people to understand. It was hard for me to believe at first, too. "The nice thing about Afrezza is it works instantly for me," said Goldstein, 66, who has had Type 1 diabetes for more than 15 years. "I take my puff after I've been eating awhile, and my blood sugar never goes really high." Before Afrezza would your rapid not cover your mealtime bolus and keep you from going really high? And what about basal insulin, what happens if you don't eat at all? Does the Afrezza market sales force not recognize that basal insulin is equally necessary? This is the part of the "story" I don't see much chatter about. I see a lot of the biggest marketing push has come from Afrezza users, who have taken to social media sites such as Twitter and Reddit to spread the word. And of course the DOC is getting a dose of this. Glad it is working so well and changing lives. I wish I could try it. But I would simply die without my basal insulin. Sam19 I still take basal... Don't think I could live without it either. It's not a huge burden to take the same shot of basal I always have 1x daily.... Being able to live like a normal human being otherwise is what the big deal is all about...crg Afrezza is not instead of basal. In fact, you have to be really stable with your basal in order to use Afrezza effectively. I have a pump for my basal, so I use Afrezza only for meals. With insulin from my pump or shots, if I eat carbs, they raise my blood sugar much faster than insulin can bring it down. Because Afrezza works immediately, I don't have to worry about those highs. Tonight, I had pasta with vegetables and cheese, I had ice cream and I took 8 units of Afrezza, and my blood sugar was 145 two hours after dinner. If I'd used my pump for that meal, my blood sugar would have been in the 200s for a long time. In fact, I would not have eaten that meal if I had to use insulin from my pump or shots.
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Post by compound26 on Jun 5, 2015 12:14:13 GMT -5
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Post by compound26 on Jun 3, 2015 21:01:05 GMT -5
I see Jenny, aka Psycho Analyst is still at it, drawing a ridiculous comparison based on the inflated cost provided in the article. She wastes no time running with that, eh. Sam has posted a comment, which partly addresses Jenny's comment. www.tudiabetes.org/forum/t/afrezza-los-angeles-times-article-3rd-june-2015/46495/4Samm19 The only real inconvenience I encountered with getting it was the pharmacy had trouble getting it processed because the doctor wrote a quantity that wasn't available, which caused a delay--- just a new drug type issue... That and getting off my butt to do a PFT... Which I actually ended up doing long after I got the prescription, but it was a bit of a hassle and I kept putting it off, and totally understand how some people just don't want to jump through a hoop. I still have pens if I ran out of afrezza, and can still get more..... Both my primary and my secondary prescription plans covered it so it didn't cost me a dime. I initially shared your concern about the prescribed quantity being to rigid and not flexible, but it hasn't really become a problem at all for me. It has changed my life in terms of management.... I'd pay cash for it if I had to instead of go back to just novolog....I say it changed my life as a t1 who managed to keep A1C in the low 5s without any real hypos... I can only imagine how liberating it'd be for someone who thus far hasn't been able to avoid the BG roller coasterPs I sold my shares of MNKD, just because I'm not sure what to expect for the company itself... But I assure you afrezza is an amazing thing and if mankind doesn't have what it takes to get it to market they'll just have to sell out to someone who does.
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