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Post by Clement on Jan 11, 2022 10:08:08 GMT -5
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Post by peppy on Jan 11, 2022 10:20:16 GMT -5
Thank you Clement. Hopefully there is good news. On heavy volume on a relative basis.  |
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Post by Clement on Jan 11, 2022 10:43:27 GMT -5
Pep, check out my edit above. UTHR acquired Revivicor in 2012.
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Post by boca1girl on Jan 11, 2022 10:55:27 GMT -5
Seeking Alpha early this morning:
Gene editing tools: Several biotech companies are developing pig organs for human transplant, with the heart used in the most recent operation coming from Revivicor, a subsidiary of United Therapeutics (NASDAQ:UTHR). The organ was modified to make it more acceptable to a human, including removing and inserting 10 genes to keep the heart from growing after the transplant. The team at the University of Maryland Medical Center also used a new drug made by Kiniksa Pharmaceuticals (NASDAQ:KNSA) to help prevent the organ from being rejected by the patient's body. Premarket: UTHR +8%; KNSA +5.8%.
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Post by jkendra on Jan 27, 2022 15:15:19 GMT -5
nypost.com/2022/01/27/cocaine-helped-pig-to-human-heart-transplant-breakthrough/Cocaine was the secret ingredient in pig-to-human heart transplantThe organ used during the groundbreaking pig-to-human heart transplant that took place earlier this month got a boost from an unlikely drug: cocaine. Now, doctors hope to see more of the party drug in transplant hospitals. Dr. Muhammad Mohiuddin, director of xenotransplantation — which refers to the process of transferring an animal organ into a human — at the University of Maryland Medical Center, spoke to Vice News about his historic work on a 57-year-old patient who became the host of a genetically modified pig heart. The heart was developed by lab company Revivicor, tweaked so that its DNA would be more amenable to a human host, then fortified with the party drug by Swedish medical tech company XVIVO, before traveling to the US. Usually, transplant organs originate from much shorter distances as they deteriorate within a few hours outside of the body. Mohiuddin explained how cocaine was used in a mixture among hormones, including cortisol and adrenaline, that keep the live tissue from spoiling during its long journey overseas to Maryland, but the proprietary solution raised flags with drug enforcement officials in the US, where cocaine has never before been used in this setting. “The cocaine name pops out because everybody thinks, ’Oh my God, what is cocaine doing in here?’ ” Mohiuddin told the outlet. Medical researchers aren’t clear on the mechanisms behind the amphetamine’s efficacy, but Mohiuddin wasn’t concerned with the “why” at the time, as the cocaine and hormone blend had bested the alternatives. SEE ALSO James Parsons receiving pig kidneys Pig-to-human kidney transplant a success in latest organ donor breakthrough “When we were not using this solution, we were getting failures within 48 hours. But when we started using this and infusing the heart with this solution, the heart became well preserved and started beating very well,” he said. A tedious permit process with the US Drug Enforcement Administration ensued. “It’s a bit of a hassle but it’s a routine procedure when importing controlled substances,” said Mohiuddin. The doctor encouraged further research on the use of cocaine in transplantation protocol in the US. “It will be a great advance if this process is approved by the regulatory agencies,” he said.
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Post by peppy on Jan 27, 2022 15:34:32 GMT -5
A numbing agent.
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Post by uvula on Jan 27, 2022 18:01:35 GMT -5
Why didn't they just transport the living pig to the hospital?
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Post by mytakeonit on Jan 27, 2022 20:14:06 GMT -5
Because the pig refused to buckle up in the first class seat.
But, that's mytakeonit
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Post by porkini on Jan 27, 2022 21:46:20 GMT -5
I'm concerned that one cocaine snorting pig will now stereotype all snorting pigs. Lol!
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Post by jkendra on Feb 16, 2022 21:11:54 GMT -5
Zoning change could speed up county’s review process for biohealth facilities
Further changes in review process, financial incentives considered
Thomas Kaufman, the senior director of corporate real estate for United Therapeutics, said during Wednesday’s briefing that roughly 20 years ago, the site of the company was a parking lot. Now, it is home to a roughly 50,000-square-foot facility.
In an interview, Kaufman said United Therapeutics is examining potential expansion opportunities at the Silver Spring location or at the corporation’s other location in Research Triangle Park in North Carolina. He declined to give more details.
Kaufman said the typical site plan approval process for projects like United Therapeutics’ is roughly two years, although some additions have happened faster. |
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Post by Clement on Feb 21, 2022 7:22:19 GMT -5
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Post by brentie on Feb 21, 2022 9:16:34 GMT -5
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Post by Clement on Feb 21, 2022 10:15:09 GMT -5
UTHR 9: am MNKD 5: pm same day |
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Post by jkendra on Mar 2, 2022 20:54:56 GMT -5
United Therapeutics Corporation to Present at the Cowen 42nd Annual Health Care Conference
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Post by jkendra on Mar 2, 2022 21:18:34 GMT -5
United Therapeutics Corporation to Present at the Cowen 42nd Annual Health Care Conference
Aerovate Therapeutics to Present at Cowen 42nd Annual Health Care Conference
AV-101 is a proprietary dry powder inhaled formulation of the anti-proliferative drug imatinib. Dosed specifically for pulmonary arterial hypertension (PAH), AV-101 is designed for delivery by an easy-to-use dry powder inhaler, directly into the lungs to maximize potential clinical benefit and limit systemic adverse effects. In a recent Phase 1 clinical trial, AV-101 was generally well-tolerated by healthy adult volunteers with no serious adverse events associated with AV-101.
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