|
Post by itellthefuture777 on Jul 8, 2021 3:51:11 GMT -5
|
|
|
Post by itellthefuture777 on Jul 8, 2021 4:03:05 GMT -5
|
|
|
Post by itellthefuture777 on Jul 8, 2021 8:24:33 GMT -5
|
|
|
Post by MnkdWASmyRtrmntPlan on Jul 8, 2021 10:22:05 GMT -5
Itell, those are great articles/video. It's great to see the TIR campaign has sprouted legs. That's great news for diabetics, and for Afrezza/MNKD.
|
|
|
Post by akemp3000 on Jul 8, 2021 11:45:26 GMT -5
Soon enough there will be hundreds, then thousands of users of the Afrezza/CGM combination getting excellent results back and sharing this with their endos and fellow diabetics. Simultaneously, pediatric use will get approval proving to doctors the safety that we've all known. It will become increasingly difficult for the big three to challenge and compete using their antiquated standards-of-care that will not deliver comparable results. A multi-billion dollar global industry is at stake. IMO, the timing might just motivate one big player to place a bet and make an offer to partner/merge/buy Afrezza or even the company. If there's another idea on how this is going to play out or how BP is going to compete using today's failing standards of care, it would be interesting to hear.
|
|
|
Post by sayhey24 on Jul 8, 2021 12:44:37 GMT -5
It would be nice if Nick Jonus included afrezza on his website. Right next to Dexcom would be nice. I wonder how much he knows about it. IMO this TIR is a big first step but after you know what your real time profile is sometimes action will be needed and there is only one real time tool for this.
Finally after years and years of talking about TIR and AGPs and the wide use of CGMs on this board, its starting to become a reality.
|
|
|
Post by itellthefuture777 on Jul 9, 2021 2:02:06 GMT -5
It would be nice if Nick Jonus included afrezza on his website. Right next to Dexcom would be nice. I wonder how much he knows about it. IMO this TIR is a big first step but after you know what your real time profile is sometimes action will be needed and there is only one real time tool for this. Finally after years and years of talking about TIR and AGPs and the wide use of CGMs on this board, its starting to become a reality. It's clear Afrezza adds at least 4 hours in range per day...or basically when it's used at meal time..don't see insulin providers other than Afrezza with in range results...at meal times...where loss of control..happens...Dexcom devices are an awesome real world real time powerful way to watch the glory..of ultra rapid Afrezza..mimic mother natures healthy pancreas...Indeed
|
|
|
Post by akemp3000 on Jul 9, 2021 6:24:37 GMT -5
It would be nice if Nick Jonus included afrezza on his website. Right next to Dexcom would be nice. I wonder how much he knows about it. IMO this TIR is a big first step but after you know what your real time profile is sometimes action will be needed and there is only one real time tool for this. Finally after years and years of talking about TIR and AGPs and the wide use of CGMs on this board, its starting to become a reality. It's clear Afrezza adds at least 4 hours in range per day...or basically when it's used at meal time..don't see insulin providers other than Afrezza with in range results...at meal times...where loss of control..happens...Dexcom devices are an awesome real world real time powerful way to watch the glory..of ultra rapid Afrezza..mimic mother natures healthy pancreas...Indeed Well put. It's hard to imagine any diabetic that would turn down simple inhalation versus shots, more than four hours a day of time-in-range, and fewer hypos. No competitor can offer this. Whereas Mannkind hasn't previously had the funds, horsepower or strong test data to get this message out, IMO diabetics using Afrezza and a CGM will. The grandiose projections by Al Mann and others years ago now seem within sight. I know it won't happen quickly but I also don't believe for a second that Afrezza is going to be limited to a niche solution as some used to suggest.
|
|
|
Post by mango on Jul 9, 2021 11:49:54 GMT -5
It's clear Afrezza adds at least 4 hours in range per day...or basically when it's used at meal time..don't see insulin providers other than Afrezza with in range results...at meal times...where loss of control..happens...Dexcom devices are an awesome real world real time powerful way to watch the glory..of ultra rapid Afrezza..mimic mother natures healthy pancreas...Indeed Well put. It's hard to imagine any diabetic that would turn down simple inhalation versus shots, more than four hours a day of time-in-range, and fewer hypos. No competitor can offer this. Whereas Mannkind hasn't previously had the funds, horsepower or strong test data to get this message out, IMO diabetics using Afrezza and a CGM will. The grandiose projections by Al Mann and others years ago now seem within sight. I know it won't happen quickly but I also don't believe for a second that Afrezza is going to be limited to a niche solution as some used to suggest. Afrezza is the safest mealtime insulin on the market, plus it delivers unmatched TIR results, no weight gain, no pain, no scarring or insulin amyloid masses, and SIGNIFICANTLY less hypoglycemic events. We all know what’s going on here. Just look at who the top ADA donors are for ADA and the financial disclosures, AACE consensus statement disclosures, and so on. The Insulin Cartel has everything to lose. These guys are pay-to-play. There’s BIG money at stake here. Only a matter of time though since you can only suppress the truth for so long!
|
|
|
Post by sayhey24 on Jul 9, 2021 12:24:54 GMT -5
Mango - its bigger than the insulin cartel. Its BP providing the SGLT-2s, DDP4s and GLP1s. Look at Merck. Their #3 revenue drug is Januvia.
The new medicare policy has probably created an unintended consequence and that is opening up the T2 market to the CGM vendors if they can convince the PCPs to by-pass steps 2 and 3 in the SoC and just prescribe afrezza. What we hoped Kendall could do with the SoC maybe the CGM vendors can do for us by selling direct to the Corporate PCP groups which keep getting bigger.
Lets see if we don't start seeing a few studies announced by CGM vendors comparing TIR between metformin, SGLT-2s, DDP4s,GLP1s and afrezza. Lets hope the heavy lifting for studies we always hoped for the CGM vendors will now do for us. Lets also hope they see this market opportunity as being as big as we do. We do know Sayer in the article the other week said it was huge. I also think Medtronic has to do something.
|
|
|
Post by harryx1 on Jul 9, 2021 12:37:03 GMT -5
|
|
|
Post by sayhey24 on Jul 9, 2021 12:47:46 GMT -5
|
|
|
Post by mango on Jul 9, 2021 16:17:17 GMT -5
Mango - its bigger than the insulin cartel. Its BP providing the SGLT-2s, DDP4s and GLP1s. Look at Merck. Their #3 revenue drug is Januvia. The new medicare policy has probably created an unintended consequence and that is opening up the T2 market to the CGM vendors if they can convince the PCPs to by-pass steps 2 and 3 in the SoC and just prescribe afrezza. What we hoped Kendall could do with the SoC maybe the CGM vendors can do for us by selling direct to the Corporate PCP groups which keep getting bigger. Lets see if we don't start seeing a few studies announced by CGM vendors comparing TIR between metformin, SGLT-2s, DDP4s,GLP1s and afrezza. Lets hope the heavy lifting for studies we always hoped for the CGM vendors will now do for us. Lets also hope they see this market opportunity as being as big as we do. We do know Sayer in the article the other week said it was huge. I also think Medtronic has to do something.
|
|
|
Post by akemp3000 on Jul 9, 2021 17:28:41 GMT -5
Yep. The horse is finally getting out of the barn and it's hard to imagine what BP is going to do about it...other than make a play!
|
|
|
Post by goyocafe on Jul 10, 2021 4:58:08 GMT -5
Yep. The horse is finally getting out of the barn and it's hard to imagine what BP is going to do about it...other than make a play! I always thought it was the cow that got out of the barn, the cat got out of the bag, and the rooster came home to roost. But I’ll take horses, cows, cats, or roosters if it means Mannkind may finally be growing some teeth, or is it growing a pair?
|
|