|
|
Post by sayhey24 on Jan 15, 2024 9:52:19 GMT -5
Thats a super video - thanks for sharing.
|
|
|
|
Post by agedhippie on Jan 15, 2024 10:02:53 GMT -5
Wow - I did not realize those little cartridges we put the insulin in are made of gold. And whats driving the $760; the plastic inhaler; plastic cartridge; insulin cost; FDKP cost; rent on the factory Tyvaso DPI is paying for; something else? ... First, that's TRx, not per box if you read the post. Second, those are all MNKD sourced numbers from their presentations and SEC filings. I have no idea of how the cost breaks down since that isn't reported but those are the numbers MNKD is reporting. |
|
|
|
Post by letitride on Jan 15, 2024 10:11:34 GMT -5
If you consider those little cartridges cost billions to get to market I would say they are easily worth there weight in gold.
|
|
|
|
Post by cretin11 on Jan 15, 2024 10:20:22 GMT -5
Thats a super video - thanks for sharing. It sure is. Bill’s done more (and continues to do more) for Afrezza than all our BOD members combined. |
|
|
|
Post by prcgorman2 on Jan 15, 2024 10:36:20 GMT -5
Lot of chatter for what was the flagship product. Feels to me like 2024 is the year in between the start of Tyvaso DPI (2023) and the year Peds trial results are released and we’ll see what the marketing looks like then. Really think things get interesting the closer we get to Tyvaso DPI for both PAH and IPF, end of (current) debt obligations, clofazimine for NTM, and Afrezza post-Peds.
|
|
|
|
Post by daisyz on Jan 15, 2024 10:59:17 GMT -5
Sad that the video only has 45 views after one year on YouTube. |
|
|
|
Post by sportsrancho on Jan 15, 2024 11:09:27 GMT -5
Sad that the video only has 45 views after one year on YouTube. It’s not something we promoted. It’s just a trial demo ( not done yet) that we want to put on our new website when we get that up. I believe it will be more detailed on Afrezza and promote the new website. I just posted it for you guys. |
|
|
|
Post by sportsrancho on Jan 15, 2024 11:31:25 GMT -5
Well, since we know that the the profit margin on Afrezza runs around 53 to 57% lets call it 60% for simplicity. Looking at 2022 for simplicity since they broke out Afrezza there, combine that with the TRx numbers from the JPM conference presentation, and we have a cost per prescription of just over $1,900. With a profit margin of 60% that means that each prescription costs MNKD $760. I don't think your numbers work. Non-profits are not working to subsidize drug companies. The pattern for that is well established and followed by every other drug company - they eat the costs. Wow - I did not realize those little cartridges we put the insulin in are made of gold. And whats driving the $760; the plastic inhaler; plastic cartridge; insulin cost; FDKP cost; rent on the factory Tyvaso DPI is paying for; something else? I am sure Bill has at one time or another asked Mike to sell direct. I would also not be surprised if Mike said he can't. However, now we have LillyDirect and Zepbound. VDex is also working with the New Mexico medical school which probably has a pharmacy. I doubt real cost to MNKD is $760 yet they joined the SSM and offered to provide for $35. As far as the non-profits having run several I see no reason as an educational diabetes program, afrezza could not be provided as part of the program. It seems just fine when the ADA does whatever they are doing through "Project Power" - which started as a true non-profit out of some Philadelphia churches. diabetes.org/project-powerFrom Bill… “Interesting exchange btw aged and Sayhey. What they might not know is that the price of Afrezza is extremely volume sensitive. So if the schedule script cost is $1900 at present volumes one could probably reduce that by 75% (a very rough guess) at high volume.” |
|
|
|
Post by lennymnkd on Jan 15, 2024 12:59:25 GMT -5
Sad that the video only has 45 views after one year on YouTube. It’s not something we promoted. It’s just a trial demo ( not done yet) that we want to put on our new website when we get that up. I believe it will be more detailed on Afrezza and promote the new website. I just posted it for you guys. That is what I meant by a hurt them to help them advertisement : 👍 done all the time … done in every product category imaginable. |
|
|
|
Post by sayhey24 on Jan 15, 2024 19:22:54 GMT -5
Wow - I did not realize those little cartridges we put the insulin in are made of gold. And whats driving the $760; the plastic inhaler; plastic cartridge; insulin cost; FDKP cost; rent on the factory Tyvaso DPI is paying for; something else? I am sure Bill has at one time or another asked Mike to sell direct. I would also not be surprised if Mike said he can't. However, now we have LillyDirect and Zepbound. VDex is also working with the New Mexico medical school which probably has a pharmacy. I doubt real cost to MNKD is $760 yet they joined the SSM and offered to provide for $35. As far as the non-profits having run several I see no reason as an educational diabetes program, afrezza could not be provided as part of the program. It seems just fine when the ADA does whatever they are doing through "Project Power" - which started as a true non-profit out of some Philadelphia churches. diabetes.org/project-powerFrom Bill… “Interesting exchange btw aged and Sayhey. What they might not know is that the price of Afrezza is extremely volume sensitive. So if the schedule script cost is $1900 at present volumes one could probably reduce that by 75% (a very rough guess) at high volume.” I have no idea where Aged got the $1900. I am a simple guy. What do you and Bill think the price is your people in New Mexico can afford out of pocket. It sounds like many don't have insurance and if they did afrezza is not going to be covered anyway. Can they afford $35 a box? Would they pay $50 or $99? Bill wants 50k scripts a week. To keep this simple let say the script is for one box - just like the old $99 Sterling deal. Lets say Mark Cuban can guarantee 200k boxes a month and MNKD cost is $25. Using the costplusdrug model the manufacturer gets 15% profit or $28.75 per box and Mark gets 15% on top of that or $33.06. Lets round up and MNKD gets $29 a box and costplusdrugs.com sells for $35. MNKD profit is $4 a box. Is that good enough to get afrezza widespread usage - $35 and 200k boxes a month? The goal is not to make a profit but rather "flood the zone" and take insurance out of the game. Leverage this 200k PWD base to get SoC coverage and open more VDexes. At $35 a box does VDex still need to prescribe the "next best thing" or can they prescribe afrezza? |
|
|
|
Post by agedhippie on Jan 15, 2024 21:13:53 GMT -5
From Bill… “Interesting exchange btw aged and Sayhey. What they might not know is that the price of Afrezza is extremely volume sensitive. So if the schedule script cost is $1900 at present volumes one could probably reduce that by 75% (a very rough guess) at high volume.” I have no idea where Aged got the $1900. I am a simple guy. ... Read my post I told you exactly how I got that number. |
|
|
|
Post by sayhey24 on Jan 16, 2024 7:34:43 GMT -5
I have no idea where Aged got the $1900. I am a simple guy. ... Read my post I told you exactly how I got that number. Whats a script? Is it 1 box or is it 3 boxes or something else. I am just trying to understand what a price per box is that Bill and Sport's people would pay so VDex does not have to look for "the next best thing". No one is paying $1k per box let alone $1900. The Sterling program at $99 is getting in the ballpark. Bill said the cost was variable based on volume. I put out the $35 number based on 200k boxes a month based on Bill's desire to get 50k scripts. Can MNKD make a box of afrezza for $25 if they were selling 200k boxes per month? The issue VDex has right now is afrezza affordability. After the kids data and Cipla data comes in the one remaining issue afrezza still has is affordability. This problem needs to be solved and its going to take a little creativity to do it as BP will do everything possible to block afrezza. Thats 28cents a cartridge. Maybe $25 is a crazy number but the price a PWD is willing to pay of $35 is not. |
|
|
|
Post by prcgorman2 on Jan 16, 2024 8:24:02 GMT -5
aged said he didn’t know what the “average script” is. None of us do.
|
|
|
|
Post by wmdhunt on Jan 17, 2024 14:07:20 GMT -5
That's a good VDEX commercial. Simple, to the point, and effective in my opinion. If there was an ad agency or advisor for this item, Mike might consider engaging them because hamburgers on a hook was dumb; again, in my opinion.
|
|
|
|
Post by ktim on Jan 18, 2024 12:11:19 GMT -5
That's a good VDEX commercial. Simple, to the point, and effective in my opinion. If there was an ad agency or advisor for this item, Mike might consider engaging them because hamburgers on a hook was dumb; again, in my opinion. You've got to have flying hamburgers or people dancing around a fountain to give time for the FDA disclaimer voice overs to be done. Take your pick, but due to FDA requirements most drug commercials are pretty lame. Of course it helps if a drug has some metric of superiority proven to the FDA's satisfaction and thus allowed mention in the commercial, which of course we know Afrezza does not. |
|
