Spiro's Early Results

[sullykraft]

Wow, amazing results. Thank you so much for sharing.

[mannmade]

Spiro as I understand it you are a T2 who is only using Afrezza. Also do I understand correctly that you were never on a GLP-1 such as Metformin? This would make you among the first to begin the paradigm shift as I understand current T2 treatment protocols generally look at products like Metformin first and then finally basal insulin. Congratulations for beginning the paradigm shift...

[Deleted]

Mar 5, 2015 18:27:02 GMT -5 mannmade said:

Spiro as I understand it you are a T2 who is only using Afrezza. Also do I understand correctly that you were never on a GLP-1 such as Metformin? This would make you among the first to begin the paradigm shift as I understand current T2 treatment protocols generally look at products like Metformin first and then finally basal insulin. Congratulations for beginning the paradigm shift...

another user who is t2

[spiro]

Mannmade,

You are exactly right, I am a Type 2 without any exposure to any diabetes medications except for Afrezza 4mg. I asked my doctor about Afrezza and we decided to give it try. Because the early results were acceptable, I will be staying on Afrezza for at least 3 months and then repeat blood work. I don't know about this paradigm shift stuff, but I sure the heck wasn't going to take Metformin. Spiro thinks the word of Afrezza will spread like wild fire from diabetic to diabetic, from doctor to doctor and then from country to country. Ok, I'm stopping before Liane thinks I'm pumping again.

Spiro

[afrizzle]

Spiro, please thank Spiro ever so much for Sprio's willingness to share Sprio's most excellent results.

[liane]

What is very significant about spiro being placed on Afrezza is that he is T2 and oral anti-diabetic naive, insulin naive. Most of the insurance plans we were seeing in the past few months had these criteria for prescribing Afrezza:

There is a diagnosis of type 2 diabetes mellitus and both criteria 1 and 2 below are met:

1.Treatment with metformin is ineffective in reducing A1C to goal of 7% or less after 90 days of therapy, unless contraindicated or not tolerated.

AND

2.Treatment with an injectable insulin regimen containing a prandial insulin (See Appendix 1) is ineffective for reducing A1C to goal of 7% or less after 90 days of therapy, unless contraindicated or not tolerated.

Now certainly if you want to pay out of pocket, you can have any drug your doctor will prescribe. But getting insurance to pay usually requires adhering to their criteria. And certainly, spiro's physician could be really good at making prior authorizations go through.

But it sounds like spiro had an extremely easy time getting this approved. The paradigm could shift faster than any of us would think possible. 

[mannmade]

Spiro now we have verification that you are indeed leading the pardigm shift... You made YMB,

franksmom44 • 2 minutes 25 seconds ago
0users liked this postsusers disliked this posts0Reply
Another new user posting results
YMB won't let me post a link but it is on proboards. Guys name is "spiro"

[savzak]

Mar 5, 2015 19:43:46 GMT -5 mannmade said:

Spiro now we have verification that you are indeed leading the pardigm shift... You made YMB,

franksmom44 • 2 minutes 25 seconds ago
0users liked this postsusers disliked this posts0Reply
Another new user posting results
YMB won't let me post a link but it is on proboards. Guys name is "spiro"

What do you know? My old MannKind pal is famous!

[spiro]

Spiro doesn't want to be famous. He wants MNKD;s share price to be much higher than his A1C level, not much lower. I am sitting here with my glucose level at 82, three hours after dinner, totally convinced that Afrezza is the real deal. It's rather obvious that something extraordinary is happening. Spiro would appreciate it, if someone could explain how he has gotten to these favorable glucose levels so quickly. He thought it would take much longer.

[liane]

The rapidity of the response should not surprise you. You're finally getting insulin precisely when you need it, and not when you don't.

[tripoley]

Mar 5, 2015 20:50:59 GMT -5 spiro said:

Spiro doesn't want to be famous. He wants MNKD;s share price to be much higher than his A1C level, not much lower. I am sitting here with my glucose level at 82, three hours after dinner, totally convinced that Afrezza is the real deal. It's rather obvious that something extraordinary is happening. Spiro would appreciate it, if someone could explain how he has gotten to these favorable glucose levels so quickly. He thought it would take much longer.

The Afrezza takes the place of your first phase insulin which your pancreas isn't doing a very good job of producing.  Your pancreas then takes over for the second phase and basal insulin which it still does okay.  Afrezza also suppresses hepatic glucose production which keeps your BS low too.  Another benefit is you are less hyperinsulinemic which would tend to cause less insulin resistance.  Oh, and btw, YOU are the exact patient many of us have been waiting for but no one will do a study on because it's not the standard of care.  It soon will be.

[kball]

Mar 5, 2015 20:50:59 GMT -5 spiro said:

Spiro doesn't want to be famous. He wants MNKD;s share price to be much higher than his A1C level, not much lower. I am sitting here with my glucose level at 82, three hours after dinner, totally convinced that Afrezza is the real deal. It's rather obvious that something extraordinary is happening. Spiro would appreciate it, if someone could explain how he has gotten to these favorable glucose levels so quickly. He thought it would take much longer.

Spiro, if its not too personal, am i right in thinking that you were first an investor in Mannkind, and diagnosed T2 at some point after?

I think you must be among the first in THAT category if this is the case.

Another trailblazer...especially not being on any other meds for it as it opens up a new frontier for doctors to now consider.
ANd patients not be afraid to bring it up and request Afrezza sooner rather than later

[spiro]

Liane and Tripoley, thanks for answering my question. Kball, don't worry, Spiro tells all. He has owned MNKD a lot longer than his diabetes diagnosis. After listening to Al Mann talk about Afrezza for so long, it was sort of a no-brainer to push my doctor try Afrezza. My insurance company has paid for the first month. We are working on month's 2 and 3. If I have to, I will pay out of pocket to continue on Afrezza.

[rockyp]

Mar 5, 2015 19:26:26 GMT -5 liane said:

What is very significant about spiro being placed on Afrezza is that he is T2 and oral anti-diabetic naive, insulin naive. Most of the insurance plans we were seeing in the past few months had these criteria for prescribing Afrezza:

There is a diagnosis of type 2 diabetes mellitus and both criteria 1 and 2 below are met:

1.Treatment with metformin is ineffective in reducing A1C to goal of 7% or less after 90 days of therapy, unless contraindicated or not tolerated.

AND

2.Treatment with an injectable insulin regimen containing a prandial insulin (See Appendix 1) is ineffective for reducing A1C to goal of 7% or less after 90 days of therapy, unless contraindicated or not tolerated.

Now certainly if you want to pay out of pocket, you can have any drug your doctor will prescribe. But getting insurance to pay usually requires adhering to their criteria. And certainly, spiro's physician could be really good at making prior authorizations go through.

But it sounds like spiro had an extremely easy time getting this approved. The paradigm could shift faster than any of us would think possible. 

liane, you forget that Spiro bought Mnkd way back before others saw the merits of Afrezza and MNKD was less than $30/share; he is flush.  

[gomnkd]

Mar 5, 2015 18:56:28 GMT -5 spiro said:

Mannmade,

You are exactly right, I am a Type 2 without any exposure to any diabetes medications except for Afrezza 4mg. I asked my doctor about Afrezza and we decided to give it try. Because the early results were acceptable, I will be staying on Afrezza for at least 3 months and then repeat blood work. I don't know about this paradigm shift stuff, but I sure the heck wasn't going to take Metformin. Spiro thinks the word of Afrezza will spread like wild fire from diabetic to diabetic, from doctor to doctor and then from country to country. Ok, I'm stopping before Liane thinks I'm pumping again.

Spiro

Gomnkd likes to know why Spiro doesn't want to take Metformin? 

Ah, I should have named my moniker Go-up-mnkd.