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Post by peppy on Mar 12, 2017 12:46:54 GMT -5
following the discussion above:
IF REversed is using afrezza, heh
Anecdotal accounts could mean something here.
Heh, physicians know insulin will put type two in remission, too dangerous to use! Until Afrezza?
weehaw
Al Mann was telling us? What a brain! |
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Post by peppy on Mar 12, 2017 12:47:48 GMT -5
And where are all these studies showing man made injectable insulin puts T2D into remission? Start with this paper (http://spectrum.diabetesjournals.org/content/29/1/50), plus it's recent so it has a good set of references. We are dogging you! You information fountain you! weehaw.
Heh, look at the title. "Case Study: Remission of Type 2 Diabetes After Outpatient Basal Insulin Therapy" Jeese Louise.
(I love the word sequelae.)
And here is the point: As the disease progresses, drug therapies are often intensified and rarely reduced to control glycemia. www.screencast.com/t/nOwBa4aaA
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Post by peppy on Mar 12, 2017 13:14:48 GMT -5
Are you kidding me?
She presented with an A1C of 17.6% (target <7%) and a fasting blood glucose (FBG) of 452 mg/dL (target 70–130 mg/dL).
In this case there was no choice but to start insulin?
One month later (July 2011), the patient’s fasting SMBG values had improved to a range of 71–212 mg/dL with a single hypoglycemic episode (58 mg/dL); her weight and BMI increased slightly to 74.1 kg and 32.9 kg/m2, respectively.
During the drug-free period of March 2012 to May 2014,
Past studies demonstrated induction of a drug-free period when patients newly diagnosed with type 2 diabetes were treated with 2–3 weeks of intensive insulin therapy.
So knowing this, have the physicians in charge of the American diabetic association considered afrezza? as the insulin initiation?
Be still my heart.
This is making me angry in every sense of the word. Physician know and have not allowed afrezza to try this? Why? www.screencast.com/t/nOwBa4aaA
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Post by agedhippie on Mar 12, 2017 15:31:16 GMT -5
Are you kidding me?
She presented with an A1C of 17.6% (target <7%) and a fasting blood glucose (FBG) of 452 mg/dL (target 70–130 mg/dL).
In this case there was no choice but to start insulin?
One month later (July 2011), the patient’s fasting SMBG values had improved to a range of 71–212 mg/dL with a single hypoglycemic episode (58 mg/dL); her weight and BMI increased slightly to 74.1 kg and 32.9 kg/m2, respectively.
During the drug-free period of March 2012 to May 2014,
Past studies demonstrated induction of a drug-free period when patients newly diagnosed with type 2 diabetes were treated with 2–3 weeks of intensive insulin therapy.
So knowing this, have the physicians in charge of the American diabetic association considered afrezza? as the insulin initiation?
Be still my heart.
This is making me angry in every sense of the word. Physician know and have not allowed afrezza to try this? Why? www.screencast.com/t/nOwBa4aaA
Look at the second paper they referenced - it was dated 1997, that's 20 years ago! This is not new stuff at all but it has never been seriously used anywhere. |
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Post by peppy on Mar 12, 2017 16:22:44 GMT -5
Are you kidding me?
She presented with an A1C of 17.6% (target <7%) and a fasting blood glucose (FBG) of 452 mg/dL (target 70–130 mg/dL).
In this case there was no choice but to start insulin?
One month later (July 2011), the patient’s fasting SMBG values had improved to a range of 71–212 mg/dL with a single hypoglycemic episode (58 mg/dL); her weight and BMI increased slightly to 74.1 kg and 32.9 kg/m2, respectively.
During the drug-free period of March 2012 to May 2014,
Past studies demonstrated induction of a drug-free period when patients newly diagnosed with type 2 diabetes were treated with 2–3 weeks of intensive insulin therapy.
So knowing this, have the physicians in charge of the American diabetic association considered afrezza? as the insulin initiation?
Be still my heart.
This is making me angry in every sense of the word. Physician know and have not allowed afrezza to try this? Why? www.screencast.com/t/nOwBa4aaA
Look at the second paper they referenced - it was dated 1997, that's 20 years ago! This is not new stuff at all but it has never been seriously used anywhere. care.diabetesjournals.org/content/20/9/1353?ijkey=d21cbf0584de29121c64a198122bb23aa9bf8944&keytype2=tf_ipsecsh
RESULTS Four patients were considered therapeutic failures since CSII failed to induce euglycemia (n = 1) or glucose control deteriorated within 6 months after CSII (n = 3). The remaining nine patients were maintained on diet alone with adequate control from 9 to > 50 months (median ± SE, 26 ± 4.8 months). In five patients, glycemic control deteriorated after 9–36 months, but a repeat 2-week CSII treatment reestablished control in four patients. One of these patients underwent a third CSII treatment 13 months later. At the time this article was written, six patients of the initial group were still controlled without medication 16–59 months (median ± SE, 45.5 ± 6.6 months) after the initiation of treatment. Body weight remained unchanged in all patients.
Euglycemia = normal glucose levels. Geeze Louise (woof)
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Post by mango on Mar 14, 2017 8:53:25 GMT -5
Too bad, the insulin companies and dexcom already work together.
Al Mann hired a man that eventually became Dexcom CEO. That same man made a fake speech in honor of Al. That same man is now a sellout, and doesn't help now that Al is gone. Lots of people quit hanging around when they can't get your money anymore
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Post by peppy on Mar 17, 2017 13:45:17 GMT -5
from the 4th quarter CC
Mike C
The next is, we’ve partnered with third-party, such as Charles Mattocks who’s putting a reality show on for diabetes on this Discovery Life in the summer. That will be one of the first time you will see our TV commercial aired. It’s part of our sponsorship. We are going to get exclusive commercials during that show.
So the more successful that show is, the more viewers will see our ad. And it’s a very targeted population, and that’s in the process of being filmed and we’ll continue to be excited about seeing that starting in July.
The next, as many of you may have seen at Damon Dash, he’s a gentlemen who is bigger than life himself. He really has a ton of passion. He’s been a Type 1 diabetic for over 30 years, and he happens to be a person taking Afrezza. He has genuinely taken an interest in the product and with diabetes and educating others around their diabetes health. He’ll be launching something called Dash diabetes network over the coming weeks and there will be targeted content launching out of that process.
And then finally, Outcome Health, which was formerly known as Context Media, I’ll talk about in a second, which is really the in-office iPads, wireless, et cetera, that you see. He is launching affective yesterday with commercials for Afrezza showing there in the office. We also will be expanding our social media capabilities, which I’ll touch on in a second.
Just a highlight, when I get the e-mails from you all on DTC and when you’re going to launch your commercial. The first is that, our market share today, you really don’t want to launch TV in a broad spectrum. You would literally be flushing your money down the toilet relative to return.
First, you’re going to need over $40 million just to launch a real TV campaign. And second, the impact from TV to prescribing is typically three to six months. And you have to have enough reach in frequency of those commercials to impact the patient at the time they’re going to see their doctor. So they see the ad and make an appointment, and you have to make sure, they’re continuing to see your ad although we have until the day they make that appointment.
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Post by sportsrancho on Mar 17, 2017 14:16:08 GMT -5
Pretty obvious this is taking off in the black community. I think it's great. Word will spread fast now.
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Post by cretin11 on Mar 17, 2017 14:43:54 GMT -5
Sports, what are you basing that on (that it's taking off in the black community)? Agree that sounds great.
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Post by Deleted on Mar 17, 2017 14:50:39 GMT -5
Sports, what are you basing that on (that it's taking off in the black community)? Agree that sounds great. Dash and Charles mattocks aren't black enough for you? ( hopefully I dont sound racist) |
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Post by cretin11 on Mar 17, 2017 14:57:23 GMT -5
Ha, i am not questioning that part of it, just wondering how we measure the extent to which it's "taking off" and what that really means, given that the TV show isn't scheduled to air until several months from now. I hope it is gonna take off, but my concern is that this TV show and our commercials will be viewed by a small audience and have a similar impact as our MLB playoffs program ads. I would love to be pleasantly surprised. I'll be tuning in for the show, assuming my cable package includes this network.
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Post by Deleted on Mar 17, 2017 15:06:51 GMT -5
Ha, i am not questioning that part of it, just wondering how we measure the extent to which it's "taking off" and what that really means, given that the TV show isn't scheduled to air until several months from now. I hope it is gonna take off, but my concern is that this TV show and our commercials will be viewed by a small audience and have a similar impact as our MLB playoffs program ads. I would love to be pleasantly surprised. I'll be tuning in for the show, assuming my cable package includes this network. yes.. taking off has certainly a degree of variation among each poster here.. sports may have to disclose her's |
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Post by sportsrancho on Mar 17, 2017 15:40:10 GMT -5
Ha, i am not questioning that part of it, just wondering how we measure the extent to which it's "taking off" and what that really means, given that the TV show isn't scheduled to air until several months from now. I hope it is gonna take off, but my concern is that this TV show and our commercials will be viewed by a small audience and have a similar impact as our MLB playoffs program ads. I would love to be pleasantly surprised. I'll be tuning in for the show, assuming my cable package includes this network. yes.. taking off has certainly a degree of variation among each poster here.. sports may have to disclose her's I was not thinking really about the TV show. I was thinking about what Mike said about Dashes passion. IMO he's probably telling every PWD he knows. Then there is the celebrity chef circuit. So many of them know each other. |
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Post by cretin11 on Mar 17, 2017 16:26:27 GMT -5
I like it. Now we just need to infiltrate the celebrity endo circuit!
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Post by mnholdem on Mar 17, 2017 17:05:37 GMT -5
At the earnings call, Mike stated their target is 30,000 doctors. That means they'll be introducing Afrezza to more HCP than just endos, since there are only 5800 board certified endos in the USA and about 2,000 of those are academics who don't see many patients.
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