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Post by Deleted on Mar 11, 2017 13:39:46 GMT -5
agedhippie "You don't get uncontrolled growth because the body is a series of interlocking systems and as one cause cell growth another kills them." Using your logic: growth in the lungs will not be an issue because of "interlocking systems". Wow!
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Post by agedhippie on Mar 11, 2017 13:51:56 GMT -5
agedhippie "You don't get uncontrolled growth because the body is a series of interlocking systems and as one cause cell growth another kills them." Using your logic: growth in the lungs will not be an issue because of "interlocking systems". Wow! Not quite The abnormal concentration is what may cause a lung issue just as it can with hyperlipotrophy. Systems have limits - you can rev an engine over the red line but then bad things are more likely to happen.
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centrn
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Post by centrn on Mar 11, 2017 14:00:24 GMT -5
So you own no shares, are a diabetic, not on Afrezza. You are on here all the time. Why? Tell me about neuropathy and diabetes.
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Post by Deleted on Mar 11, 2017 14:12:32 GMT -5
agedhippie "systems have limits" so injecting: day after day, week after week, month after month, year after year, the body reabsorbs the fat and it goes away? One does not have enough sites to inject into to allow this, unless you have an infinite skin area to inject into. Enlighten me: how does the body reabsorb fat? Cannot wait to hear this one!
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Post by agedhippie on Mar 11, 2017 15:48:58 GMT -5
agedhippie "systems have limits" so injecting: day after day, week after week, month after month, year after year, the body reabsorbs the fat and it goes away? One does not have enough sites to inject into to allow this, unless you have an infinite skin area to inject into. Enlighten me: how does the body reabsorb fat? Cannot wait to hear this one! Ok - so I'm being trolled. Sophie was right. Lol.
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Post by dreamboatcruise on Mar 11, 2017 16:14:22 GMT -5
Long term studies still need to be done. However... due to the delays in approval and now marketing, there are people that have been using Afrezza for many years. The studies and patient experience clearly sets an expectation that lung pathology is by no means a common occurrence. If anything it appears the immuno response is the more likely, but if real extremely rare, problem compared to growth factor issues.
The way bodies work, every drug is going to cause something bad to some people. Bodies aren't perfect and any change has the potential to set in motion undesirable repercussions. As pointed out above, our bodies have self correcting mechanisms (cell growth vs cell destruction, etc.)... and when they work perfectly they handle just about everything we throw at them... sadly, none of our bodies are perfect. Injected insulin causes problems and I'd be shocked if Afrezza doesn't have the rare undesirable side effect as well... as every drug I know of does.
The question is risk vs benefit. So far it seems Afrezza has a very high benefit to risk ratio within the drug world.
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Post by Deleted on Mar 12, 2017 6:53:31 GMT -5
agedhippie "systems have limits" so injecting: day after day, week after week, month after month, year after year, the body reabsorbs the fat and it goes away? One does not have enough sites to inject into to allow this, unless you have an infinite skin area to inject into. Enlighten me: how does the body reabsorb fat? Cannot wait to hear this one! Ok - so I'm being trolled. Sophie was right. Lol. You are not being "trolled", just squashing FUD. So, how does the body reabsorb fat???
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Post by peppy on Mar 12, 2017 9:11:11 GMT -5
Long term studies still need to be done. However... due to the delays in approval and now marketing, there are people that have been using Afrezza for many years. The studies and patient experience clearly sets an expectation that lung pathology is by no means a common occurrence. If anything it appears the immuno response is the more likely, but if real extremely rare, problem compared to growth factor issues. The way bodies work, every drug is going to cause something bad to some people. Bodies aren't perfect and any change has the potential to set in motion undesirable repercussions. As pointed out above, our bodies have self correcting mechanisms (cell growth vs cell destruction, etc.)... and when they work perfectly they handle just about everything we throw at them... sadly, none of our bodies are perfect. Injected insulin causes problems and I'd be shocked if Afrezza doesn't have the rare undesirable side effect as well... as every drug I know of does. The question is risk vs benefit. So far it seems Afrezza has a very high benefit to risk ratio within the drug world. Quote: The way bodies work, every drug is going to cause something bad to some people. Reply: you know you are correct. Remember aspirin went out of vogue for all the stomach ulcers. Not to mention the blood thinning. The list goes on.
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Post by Deleted on Mar 12, 2017 9:25:09 GMT -5
agedhippie "You don't get uncontrolled growth because the body is a series of interlocking systems and as one cause cell growth another kills them." Using your logic: growth in the lungs will not be an issue because of "interlocking systems". Wow! Not quite The abnormal concentration is what may cause a lung issue just as it can with hyperlipotrophy. Systems have limits - you can rev an engine over the red line but then bad things are more likely to happen. you are better off calling it a day. there is no point.
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Post by peppy on Mar 12, 2017 9:33:57 GMT -5
Not quite The abnormal concentration is what may cause a lung issue just as it can with hyperlipotrophy. Systems have limits - you can rev an engine over the red line but then bad things are more likely to happen. you are better off calling it a day. there is no point. projection
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Post by agedhippie on Mar 12, 2017 9:48:28 GMT -5
Not quite The abnormal concentration is what may cause a lung issue just as it can with hyperlipotrophy. Systems have limits - you can rev an engine over the red line but then bad things are more likely to happen. you are better off calling it a day. there is no point. I had worked that out
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Post by agedhippie on Mar 12, 2017 9:59:41 GMT -5
you are better off calling it a day. there is no point. projection Kastanes is just trolling (at least I hope he is and doesn't believe argument) and I am fine with that. Hyperlipotrophy is defined by it's transient nature, in other words that the insulin causes a fat growth in the injection site and that ceasing to inject lets the fat be absorbed and the growth dissipate - this is a medical fact not speculation. Kastanes triumphantly announcing that he has alternative facts and doesn't believe in medical facts really makes discussing medical facts with him a bit pointless.
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Post by peppy on Mar 12, 2017 10:02:44 GMT -5
I love you age, I am not trolling you. You are a fountain of information and I respect you for it. You know that I know, diabetics make their own decisions. Just like I make my own decisions.
So thank you
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Post by Deleted on Mar 12, 2017 10:12:25 GMT -5
agedhippie "Hyperlipotrophy is defined by it's transient nature, in other words that the insulin causes a fat growth in the injection site and that ceasing to inject lets the fat be absorbed and the growth dissipate - this is a medical fact not speculation." So, insulin causes fat growth which implies pancreatic insulin is causing fat to grow throughout the body. Okay!
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Post by agedhippie on Mar 12, 2017 10:18:26 GMT -5
I love you age, I am not trolling you. You are a fountain of information and I respect you for it. You know that I know, diabetics make their own decisions. Just like I make my own decisions.
So thank you
Thank you. All I really care about is that people make an informed decision, and provided they do that their decision is to be respected.
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