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Post by compound26 on Mar 9, 2017 17:17:15 GMT -5
www.afrezzajustbreathe.com/tv-news-report-on-afrezza/www.tudiabetes.org/forum/t/afrezza-question/59564/10?u=charles5Inhaled Insulin Is Quick & Easy To Use, But Is It A Game-Changer?
March 8, 2017 5:45 PM By Dr. Maria Simbra pittsburgh.cbslocal.com/2017/03/08/inhaled-insulin-is-quick-easy-to-use-but-is-it-a-game-changer/PITTSBURGH (KDKA) – Could insulin that you inhale, instead of inject be a game-changer for diabetics? For some people with diabetes, injecting insulin is the only way to keep their blood sugars under control. What if there was another way? “When you inhale something, it gets in the body very quickly, and works very quickly, and then goes away quickly,” Dr. Wayne Evron, a diabetes specialist at St. Clair Hospital, said. Inhaled insulin is a quicker, easier way to get the medicine into your body. People get less of a spike in blood sugar after eating. Inhaled insulin came about six years ago, and has undergone some refinement. The initial versions were linked to a decrease in lung function at six months, and had to be taken off the market. Even with the current version, doctors have to watch carefully how well the lungs work. “Even now, any inhaled insulin, you still have to make sure they don’t have COPD or any other lung problem. And, you still have to measure lung function before and during. So, that’s a deterrent a little bit to doctors,” Dr. Evron said. The device looks like an inhaler. You insert capsules of insulin in different doses, depending on your needs based on blood sugar readings. “There are some preparations you have to do. You have to put a capsule in the bottle, you have to measure it right, not that you don’t have to measure insulin, but it’s a little more involved,” Dr. Evron said. “The advantage, I guess is that people don’t like to take shots.” It tends to be more popular with his younger, more tech savvy patients. But even so, it isn’t for most of them. “We live in Pittsburgh. And, there’s a lot of COPD both from smoking as well as pollutants,” Dr. Evron said. It’s also about double the cost of injectable insulin. “Very few insurances are paying for it now. Because it’s very expensive,” Dr. Evron said. There are a few case reports of cancer. “It’s irritating. Insulin is a growth hormone. So, when you put insulin in the lung, there’s always that fear that you get growth of lung tissue as well,” Dr. Evron said. It also may not work well in the long run. “It’s in a foreign place. So, the body attacks it. So, there was some worry about anti-insulin antibodies forming from this. So yes, the question is this could become less effective with time?” Dr. Evron said.
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Post by dreamboatcruise on Mar 9, 2017 17:32:18 GMT -5
Started out good, but dragging up a lot of issues that have already been addressed by studies and trials.
Interesting on the pricing issue as well. Hard to know what comparison he is making.
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Post by cjm18 on Mar 9, 2017 17:41:13 GMT -5
"The advantage I guess is no shots".... this is one of the problems. Doctors don't understand why it's better. There's no way I would switch from injectable after reading this unless I hated needles.
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Post by goyocafe on Mar 9, 2017 17:48:15 GMT -5
"The advantage I guess is no shots".... this is one of the problems. Doctors don't understand why it's better. There's no way I would switch from injectable after reading this unless I hated needles. Get me that friggin' label change!!!!! |
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Post by dreamboatcruise on Mar 9, 2017 17:58:47 GMT -5
"The advantage I guess is no shots".... this is one of the problems. Doctors don't understand why it's better. There's no way I would switch from injectable after reading this unless I hated needles. But it seems like he forgets what he's talking about half way through... or his statements were simply butchered in editing. He started out with... “When you inhale something, it gets in the body very quickly, and works very quickly, and then goes away quickly,” Dr. Wayne Evron, a diabetes specialist at St. Clair Hospital, said. I suppose he could say that and yet not view that as an advantage? Strange! |
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Post by agedhippie on Mar 9, 2017 18:05:49 GMT -5
"The advantage I guess is no shots".... this is one of the problems. Doctors don't understand why it's better. There's no way I would switch from injectable after reading this unless I hated needles. But it seems like he forgets what he's talking about half way through... or his statements were simply butchered in editing. He started out with... “When you inhale something, it gets in the body very quickly, and works very quickly, and then goes away quickly,” Dr. Wayne Evron, a diabetes specialist at St. Clair Hospital, said. I suppose he could say that and yet not view that as an advantage? Strange! Because it's not necessarily an advantage. If he is used to IV delivered insulin then he knows the problems of fast in/fast out insulins. Quick clearance is great for corrections, but not so good for meals. |
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Post by kc on Mar 9, 2017 18:25:44 GMT -5
I don't like his knowledge or comments. So I went to check and see if he was a paid representative of a another big Pharma. But he has been paid very little. $3,200. openpaymentsdata.cms.gov/physician/242728/payment-information Many of the endocrinologist are in the six-figure range with payments. from pharma's |
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Post by peppy on Mar 9, 2017 19:18:53 GMT -5
I don't like his knowledge or comments. So I went to check and see if he was a paid representative of a another big Pharma. But he has been paid very little. $3,200. openpaymentsdata.cms.gov/physician/242728/payment-information Many of the endocrinologist are in the six-figure range with payments. from pharma's He seems to be working on a bonus. |
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Post by peppy on Mar 9, 2017 19:19:51 GMT -5
www.afrezzajustbreathe.com/tv-news-report-on-afrezza/www.tudiabetes.org/forum/t/afrezza-question/59564/10?u=charles5Inhaled Insulin Is Quick & Easy To Use, But Is It A Game-Changer?
March 8, 2017 5:45 PM By Dr. Maria Simbra pittsburgh.cbslocal.com/2017/03/08/inhaled-insulin-is-quick-easy-to-use-but-is-it-a-game-changer/PITTSBURGH (KDKA) – Could insulin that you inhale, instead of inject be a game-changer for diabetics? For some people with diabetes, injecting insulin is the only way to keep their blood sugars under control. What if there was another way? “When you inhale something, it gets in the body very quickly, and works very quickly, and then goes away quickly,” Dr. Wayne Evron, a diabetes specialist at St. Clair Hospital, said. Inhaled insulin is a quicker, easier way to get the medicine into your body. People get less of a spike in blood sugar after eating. Inhaled insulin came about six years ago, and has undergone some refinement. The initial versions were linked to a decrease in lung function at six months, and had to be taken off the market. Even with the current version, doctors have to watch carefully how well the lungs work. “Even now, any inhaled insulin, you still have to make sure they don’t have COPD or any other lung problem. And, you still have to measure lung function before and during. So, that’s a deterrent a little bit to doctors,” Dr. Evron said. The device looks like an inhaler. You insert capsules of insulin in different doses, depending on your needs based on blood sugar readings. “There are some preparations you have to do. You have to put a capsule in the bottle, you have to measure it right, not that you don’t have to measure insulin, but it’s a little more involved,” Dr. Evron said. “The advantage, I guess is that people don’t like to take shots.” It tends to be more popular with his younger, more tech savvy patients. But even so, it isn’t for most of them. “We live in Pittsburgh. And, there’s a lot of COPD both from smoking as well as pollutants,” Dr. Evron said. It’s also about double the cost of injectable insulin. “Very few insurances are paying for it now. Because it’s very expensive,” Dr. Evron said. There are a few case reports of cancer. “It’s irritating. Insulin is a growth hormone. So, when you put insulin in the lung, there’s always that fear that you get growth of lung tissue as well,” Dr. Evron said. It also may not work well in the long run. “It’s in a foreign place. So, the body attacks it. So, there was some worry about anti-insulin antibodies forming from this. So yes, the question is this could become less effective with time?” Dr. Evron said. Compound your site is the best! <----- frequent visitor
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Post by sayhey24 on Mar 9, 2017 19:33:56 GMT -5
But it seems like he forgets what he's talking about half way through... or his statements were simply butchered in editing. He started out with... “When you inhale something, it gets in the body very quickly, and works very quickly, and then goes away quickly,” Dr. Wayne Evron, a diabetes specialist at St. Clair Hospital, said. I suppose he could say that and yet not view that as an advantage? Strange! Because it's not necessarily an advantage. If he is used to IV delivered insulin then he knows the problems of fast in/fast out insulins. Quick clearance is great for corrections, but not so good for meals. It would be really nice if when these news shows cover afrezza our CCO works with them to get a doctor who knows what they are talking about. That was a disaster. Inhaling Exubera did not make it work faster. In fact it did not work any better than injected short-acting insulin. What makes afrezza work faster is that it is the exact same monomer insulin the pancreas secretes. Now, the pancreas must think fast action to provide that phase 1 insulin release to signal the liver is a good thing and is a must during meals for the body to work correctly. Quick clearance is also needed for the liver to work correctly to counter over dosing the amount of insulin needed. Having some analog hanging around is like that guest who came for a day and is still there a week later. |
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Post by kc on Mar 9, 2017 19:39:08 GMT -5
The company should contact that particular TV station and that doctor and try to present a different view of the product. The TV station might be willing to listen to it to update their report.
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Post by gamblerjag on Mar 9, 2017 20:24:50 GMT -5
i see this article as one of the worse articles that gives the illusion of pro- afrezza. I don't see this guy as an advocate... AT ALL
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Post by mnholdem on Mar 9, 2017 20:34:35 GMT -5
“There are some preparations you have to do. You have to put a capsule in the bottle, you have to measure it right, not that you don’t have to measure insulin, but it’s a little more involved,” Dr. Evron said.
A capsule in a bottle? This author apparently doesn't realize that he's talking about the disadvantages of Exubera, an inhaled insulin that was pulled off the market many years ago. 
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Hey, doc, you need to do better research before you publish. Afrezza doesn't use capsules. Afrezza doesn't come in a bottle. The delivery device is a cartridge that is inserted into a whistle-size inhaler. Snap. Click. Inhale. Simple.
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Post by agedhippie on Mar 9, 2017 20:43:09 GMT -5
“There are some preparations you have to do. You have to put a capsule in the bottle, you have to measure it right, not that you don’t have to measure insulin, but it’s a little more involved,” Dr. Evron said.
A capsule in a bottle? This author apparently doesn't realize that he's talking about the disadvantages of Exubera, an inhaled insulin that was pulled off the market many years ago.
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Hey, doc, you need to do better research before you publish. Afrezza doesn't use capsules. Afrezza doesn't come in a bottle. The delivery device is a cartridge that is inserted into a whistle-size inhaled. Snap. Click. Inhale. Simple.
I was wondering what the bottle was about! |
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Post by slugworth008 on Mar 9, 2017 20:55:06 GMT -5
"The advantage I guess is no shots".... this is one of the problems. Doctors don't understand why it's better. There's no way I would switch from injectable after reading this unless I hated needles. But it seems like he forgets what he's talking about half way through... or his statements were simply butchered in editing. He started out with... “When you inhale something, it gets in the body very quickly, and works very quickly, and then goes away quickly,” Dr. Wayne Evron, a diabetes specialist at St. Clair Hospital, said. I suppose he could say that and yet not view that as an advantage? Strange! What he forgot to say was that - He's been paid off by the BP cartel. |
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