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Post by peppy on Mar 24, 2017 18:14:42 GMT -5
Quote: I see this as good news since ultra rapid insulin plus basal now exists as an invention presumably means mnkd can refer to the combined therapy as being a use of 'ultra rapid insulin', given that TI is FDA approved, basals are FDA approved, and the combined regime is a patented invention concerning one type of use of ultra rapid insulin.
Reply: dumb this down for me. when you say ultra rapid and basal now exists as an invention. Name the ultra rapid part? name the basal part of the invention? I want to make sure I understand.
Hi Peppy Looking at the initial summary paragraph it says: Disclosed herein are improved methods of treating hyperglycemia with a combination of an ultrarapid acting insulin and insulin glargine comprising prandial administration of the ultrarapid insulin, and administration of a first dose of insulin glargine within 6 hours of waking for a day. In other words the patented invention is the method namely treatment with what the patent defines (as a term of art) 'ultrarapid' prandial insulin, plus glargine daily. Hence the patented invention is that form of combination therapy. As I think it to be, this means that the patented combination therapy can be referred to with physicians since it consists of fda approved drugs (so no worries using them) and the invention is simply the patented method which uses certain terms per the patent (you could equally say 'part one and part two' for TI and basal respectively, if that's what the patent said, or "head" and "handle" if someone invented a combination tool with a wooden shaft plus a heavy metal bit for bashing nails in called a "hammer"). I think that means 'ultrarapid' is therefore ok as an expression to describe the first part of the therapy when this dual treatment is used. But then what do I know, I'm not a US lawyer, don't take my view as more than for the purposes of discussion, for fun only, the value of your life can go down as well as up, not FDIC protected, and the lifestyle you ordered is out of stock. Terms and conditions apply, see website for details, E and OE (etc).. you are brilliant. I had read it, and made an assumption that the meaning was in addition to long acting or basal meaning subq. I see what you mean. It is right before my eyes. Thank you. So it spells out afrezza is a mealtime and needs to be used on combination with basal. Dual treatment. We know mealtime and basal are a treatment option on the standards of care, plus metformin. If physicians started ordering/prescribing that treatment option (combination injectables) it is there.
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Post by sayhey24 on Mar 24, 2017 18:14:52 GMT -5
The thing is that description has no standing medically, you can call it what you like in a patent. If you try to use it in sales though the FDA will be on you like a ton of bricks. I think MNKD should give it a try. I suspect with the new government and Trump getting an ear full from Cummings last week they just may like having a new American company which makes insulin and which can replace most of the current RAA sales. After today Trump needs a win and announcing a huge deal for insulin from an American company for medicare/medicaid/VA could put a smile on his face. Danbury once projected 4000 new jobs making afrezza. Thats way high as the manufacturing is fully automated but its a nice number to use in a press conference.
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Post by drman7 on Mar 25, 2017 19:33:42 GMT -5
Patents are challenged all the time when infringed. My ex-partner had a company he keep going for years challenging digital photocell infringement. Your cell phone which has that camera. He had the patent until it expired. In this case no one else has monomer insulin. Victoria's comment about the use of Ultra rapid is interesting. While I never liked it Mannkind now has a patent which grants its use. I am not sure the FDA can now stop them from using it. If I where Matt I would put out an Ad and run it by the FDA with the patent number and see what they do. If they challenge it I would probably file suit since its patent approved. Infringement, I gotcha. I thought ya'll meant something else. Al talked publicly a lot about his "team" researching patents and also making sure they aren't infringing. Technosphere was originally an anti-bioterrorism patent and one of a kind. I wonder when they will file for granting the heat-stable patent. Hmm. Such a great patent. Would be used with TechnoVax's vaccines, could be used with Afrezza, Mintaka's oxytocin. I know that other company that has a heat-stable inhaled oxytocin doesn't have anything close to what MannKind does. MannKind has the best inhaler, they have patents for a multi-dose inhaler as well. It is round, holds mulitple cartridges. MannKind has a lot of patent applications brewing. Ready to be filed at the right time? Maybe when everything falls into place? Al Mann talked about building a better mousetrap... Hi Mango..is there a topic on this board regarding Technosphere developed for anti-bioterrorism. I believe that Technosphere is the key for MNKD. Afrezza is just the like the Tesla Roadster which did not sell much but once the Model S came out the stock just went crazy and look at Tesla now (besides the fact the company is not profitable).
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Post by mango on Mar 25, 2017 19:46:03 GMT -5
Infringement, I gotcha. I thought ya'll meant something else. Al talked publicly a lot about his "team" researching patents and also making sure they aren't infringing. Technosphere was originally an anti-bioterrorism patent and one of a kind. I wonder when they will file for granting the heat-stable patent. Hmm. Such a great patent. Would be used with TechnoVax's vaccines, could be used with Afrezza, Mintaka's oxytocin. I know that other company that has a heat-stable inhaled oxytocin doesn't have anything close to what MannKind does. MannKind has the best inhaler, they have patents for a multi-dose inhaler as well. It is round, holds mulitple cartridges. MannKind has a lot of patent applications brewing. Ready to be filed at the right time? Maybe when everything falls into place? Al Mann talked about building a better mousetrap... Hi Mango..is there a topic on this board regarding Technosphere developed for anti-bioterrorism. I believe that Technosphere is the key for MNKD. Afrezza is just the like the Tesla Roadster which did not sell much but once the Model S came out the stock just went crazy and look at Tesla now (besides the fact the company is not profitable). Compositions for treatment or prevention of bioterrorismType: Grant Filed: January 17, 2003 Date of Patent: January 31, 2006 Assignee: MannKind Corporation Inventors: Solomon S. Steiner, Cohava Gelber, Robert S. Feldstein, Roderike Pohl patents.justia.com/patent/6991779
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