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Post by goyocafe on Mar 22, 2018 8:52:56 GMT -5
That makes sense...consistent delivery of the desired API dosage may be one of the biggest benefits of pulmonary delivery technology. And you can take it with grapefruit juice!  |
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Post by brotherm1 on Mar 23, 2018 22:10:37 GMT -5
That makes sense...consistent delivery of the desired API dosage may be one of the biggest benefits of pulmonary delivery technology. Yes, consistent delivery of the desired API dosage would be the greatest benefit (along with not being interfered with by food such as would be in the case of digestables). Pennsylvania just started medical marijuana prescriptions for about 17 different afflictions, including afflictions such as epilepsy and autism which I would think it very important to treat with more precise amounts and no greater than needed. Also, with so many patients of medical marijuana driving, the DUI laws pertaining to drugs other than alcohol are being more closely enforced. I don’t recall the specific limit in Pennsylvania, for example for driving under the influence of marijuana that I recently saw, but there is a statutory legal limit measured in parts per milliliter. I’m hoping RLS is also working on inhalation other than just for Drobinal which is cannabinol based. The THC combined with cannabinol produces the best medical results. I was very surprised recently when I read through all of the medical marijuana treatments legalized in Pennsylvania to find out almost all have a much greater percentage of THC than CBD (with the exception of the skin cancer treatment, named after the Canadian that successfully discovered and used it to cure his skin cancer (which is CBD based). The orals and vapable oils and waxes (and possibly soon smokable as is being considered), the latter two of which are extremely potent (not talking old time rag weed here), would in no way be quantifiable as would be a quantifiable dose such as RLS - I’m assuming - is working with. |
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Post by brotherm1 on Mar 23, 2018 22:49:39 GMT -5
Pennsylvania’s available medical marijuana forms. Note the majority are THC and little CBD. Thus I hope RLS will also be working in the THC market. “Keystone Kush, wax and shatter: Here's what medical marijuana products you can find in Pa. Posted February 17, 2018 at 07:02 AM | Updated February 17, 2018 at 12:11 PM Medical marijuana became available for purchase in Pennsylvania on Feb. 15, and a total of six dispensaries are opening across the state this week. But there has been much secrecy surrounding pricing of products and patients who walk into a dispensary for the first time might be overwhelmed by the different forms available. While dispensary staff can provide case-by-case guidance, here is a look at the basics: what the different forms mean, what benefits they provide and how much they cost. This list includes items available at the Cresco Yeltrah store in Butler. Cannabis contains many compounds. Here are brief descriptions of some terms most useful in understanding the differences between medical marijuana products: THC: Tetrahydrocannabinol is known as the cannabinoid that produces a "high." It binds to the areas of the brain that manage pain, emotions, appetite, nausea and sleep. CBD: Cannabidiol does not have psychoactive properties but has been shown to calm nerves, relieve pain and have anti-convulsive effects. Terpenes: These are the oils that give marijuana its aroma and taste. Bio Jesus THC: 78.3% CBD: 1.9% 0.5 gram: $45 1 gram: $75 Sojay Haze THC: 62.5% CBD: 3.1% Terpenes: 5.4% 0.5 gram: $55 1 gram: $85 Cresco Cookies THC: 65.6% CBD: 4.9% Terpenes: 2.1% 0.5 gram: $55 1 gram: $85 Durban THC: 57.3% CBD: 2.7% Terpenes: 1% 0.5 gram: $55 1 gram: $85 Blueberry THC: 70.3% CBD: 2.7% Terpenes: 5.9% 0.5 gram: $55 1 gram: $85 ]Shatter This form is smooth, clear and solid. It's the most potent form of medical marijuana because it goes through two extraction processes. Bio Jesus THC: 89.3% CBD: 1.9% Terpenes: 0.7% 0.5 gram: $50 1 gram: $80 .RSO Rick Simpson Oil is named after a Canadian who documented his extraction process to treat his skin cancer. It can be applied topically or taken orally. Harlequin 1:1 THC: 31.9% CBD: 35.4% 500mg syringe: $65 DJ Flo THC: 62.1% CBD: 0% 500mg syringe: $65 Chunky Diesel THC: 73.1% CBD: 0% 500mg syringe: $65 GG #4 THC: 70.6% CBD: 0% 500mg syringe: $65 Capsules Medical marijuana is also available in pill form CBD 1:1 THC: 100mg CBD: 100mg 10 pack: $45 Vape pens and cartridges There are a few kinds of vape cartridges available: e-liquid, CO2 and liquid live resin. These forms are produced differently but are consumed in the same fashion: the extract is heated in a pen or cartridge until the active components vaporize and can be inhaled. Blueberry (e-liquid) THC: 39.7% CBD: 0% 250mg pen: $30 Cappuccino (e-liquid) THC: 44.2% CBD: 1.3% 250mg pen: $30 Orange Mango (e-liquid) THC: 42.1% CBD: 0% 250mg pen: $30 1:1 Harlequin (CO2) THC: 32.7% CBD: 27.8% 500mg cartridge: $80 Pineapple Express (CO2) THC: 56% CBD: 0% 500mg cartridge: $80 Bio Jesus (CO2) THC: 35.4% CBD: 10% 500mg cartridge: $80 Katsu Bubba Kush (CO2) THC: 52.1% CBD: 3.7% 500mg cartridge: $80 Northern Lights #5 (CO2) THC: 52.1% CBD: 6.6% 500mg cartridge: $95 Lime Skunk (liquid live resin) THC: 69.4% CBD: 1.9% 250mg pen: $40 500mg cartridge: $70 Blueberry (liquid live resin) THC: 63.6% CBD: 0% 250mg pen: $40 500mg cartridge: $70 Keystone Kush (liquid live resin) THC: 67.6% CBD: 0% 250mg pen: $40 500mg cartridge: $70 Durban (liquid live resin) THC: 66.7% CBD: 0% 500mg cartridge: $70 Kosher Tangie (liquid live resin) THC: 67.1% CBD: 1.2% 500mg cartridge: $70 Alien Bubba (liquid live resin) THC: 69% CBD: 1.8% 500mg cartridge: $70 Joliet Jake (liquid live resin) THC: 67.4% CBD: 1.5% 500mg cartridge: $95 Lime Sorbet (liquid live resin) THC: 66.2% CBD: 2.3% 500mg cartridge: $95 Blueberry Space Cake (liquid live resin) THC: 62.4% CBD: 1.6% 500mg cartridge: $95” www.pennlive.com/news/2018/02/medical_marijuana_names_prices_pa.html |
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Post by brotherm1 on Mar 24, 2018 9:59:32 GMT -5
My above: “Pennsylvania’s available medical marijuana forms. Note the majority are THC and little CBD. Thus I hope RLS will also be working in the THC market”
Upon further reading I found dronabinol/marinol is a cannabinoid - and not a simply a CBD,, cannabidiol - if any but does have THC as I was hoping. Thus it appears RLS will be in the THC market as I was hoping (albeit it is synthetic form of the natural THC found in the plant). Sorry for any confusion. I’m stressed out. Perhaps I myself should go light one up (cannabis, cannabidiol, cannabinol, tetrahydrocannibinol....I think whomever came up with these names for these different chemicals might have been ingesting them at the same time).
And since dronabinol was already approved by the FDA in 1985 (at least for the treatment of cancer treatment side effects, and then for anorexia associated with weight loss in patients with AIDS.) RLS might be closer than we might think to a viable and salable measured- dronabinol-inhalation product?
PS where’s our expert Mango?
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Post by akemp3000 on Mar 24, 2018 11:28:24 GMT -5
This technical language is over my head. I suspect Andrea Leone Bay joined RLS because of her deep understanding of how TS could provide fast relief for serious symptoms from serious issues; i.e. migraines, cancer, cardio-pulmonary and possibly more. The pain relief use seems to have originated from Al's wife suffering from severe migraines and we know how Al dedicated his life trying to tackle the biggest health issues. I'm doubtful RLS intentions have ever had anything to do with getting high. Has the recent information found for RLS clarified exactly what they're working towards? I apologize if this has already been answered.
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Post by digger on Mar 25, 2018 1:09:15 GMT -5
Does RLS have a lab somewhere or are they using Mannkind's? Their business address is a suburban house, and I presume they're not doing any lab work there.
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Post by brotherm1 on Mar 25, 2018 11:10:00 GMT -5
This technical language is over my head. I suspect Andrea Leone Bay joined RLS because of her deep understanding of how TS could provide fast relief for serious symptoms from serious issues; i.e. migraines, cancer, cardio-pulmonary and possibly more. The pain relief use seems to have originated from Al's wife suffering from severe migraines and we know how Al dedicated his life trying to tackle the biggest health issues. I'm doubtful RLS intentions have ever had anything to do with getting high. Has the recent information found for RLS clarified exactly what they're working towards? I apologize if this has already been answered. akemp: page 20 investors.mannkindcorp.com/static-files/e2aba247-3760-43ca-8312-10e46e8ee001 |
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Post by akemp3000 on Mar 25, 2018 12:28:58 GMT -5
Thanks! I had to look up CINV but now I know.
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Post by uvula on Mar 25, 2018 20:11:21 GMT -5
Does RLS have a lab somewhere or are they using Mannkind's? Their business address is a suburban house, and I presume they're not doing any lab work there. Why not? Most meth labs are in suburban houses. |
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Post by mnholdem on Mar 25, 2018 20:39:56 GMT -5
Andrea Leone-Bay, Chief Scientific Officer for Receptor Life Sciences, still has her home address in Ridgefield CT, which is just a few miles SE of Danbury. I remember reading that MannKind has a research lab on the grounds of their Danbury manufacturing facility. 'Nuff said?  |
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Post by mango on Mar 25, 2018 20:56:29 GMT -5
Does RLS have a lab somewhere or are they using Mannkind's? Their business address is a suburban house, and I presume they're not doing any lab work there. Yes, they are are Mannkind. I mean, yes, they are at MannKind. License and lab were under Ray's name at the time. |
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Post by dreamboatcruise on Mar 26, 2018 16:02:20 GMT -5
My above: “Pennsylvania’s available medical marijuana forms. Note the majority are THC and little CBD. Thus I hope RLS will also be working in the THC market” Upon further reading I found dronabinol/marinol is a cannabinoid - and not a simply a CBD,, cannabidiol - if any but does have THC as I was hoping. Thus it appears RLS will be in the THC market as I was hoping (albeit it is synthetic form of the natural THC found in the plant). Sorry for any confusion. I’m stressed out. Perhaps I myself should go light one up (cannabis, cannabidiol, cannabinol, tetrahydrocannibinol....I think whomever came up with these names for these different chemicals might have been ingesting them at the same time). And since dronabinol was already approved by the FDA in 1985 (at least for the treatment of cancer treatment side effects, and then for anorexia associated with weight loss in patients with AIDS.) RLS might be closer than we might think to a viable and salable measured- dronabinol-inhalation product? PS where’s our expert Mango? It appears they haven't yet started any clinical trials. |
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Post by brotherm1 on Mar 26, 2018 16:45:23 GMT -5
I’ve done some searching also, on the clinical trials website. Perhaps they hid it well or perhaps they are doing it in another country, or perhaps a combination of the aforementioned and by another company such as GW Pharma, or something. Or something.
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Post by uvula on Mar 27, 2018 7:36:33 GMT -5
Not clever enough to satisfy the trademark office but able to conduct a secret clinical trial. Not likely.
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Post by sportsrancho on Mar 27, 2018 8:51:45 GMT -5
This thread gives me a headache!
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