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Post by rockstarrick on Mar 15, 2018 0:57:59 GMT -5
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Post by mnholdem on Mar 15, 2018 4:37:46 GMT -5
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Post by boca1girl on Mar 15, 2018 8:37:04 GMT -5
Mannkind should clarify RLS’s involment and correct if it’s wrong. Mike keeps promising information about RLS but we are still waiting.
I wonder if RLS will still be listed on the next set of presentation slides. I did see Andrea Bay-Lione’s (sp) name mentioned in the trial info.
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Post by mnholdem on Mar 15, 2018 11:36:20 GMT -5
I looked an couldn't find a direct reference to Andrea. Where exactly did you discover it? Under links found in the Resources section?
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Post by boca1girl on Mar 15, 2018 14:53:01 GMT -5
I looked an couldn't find a direct reference to Andrea. Where exactly did you discover it? Under links found in the Resources section? I could be confused with the STAT study. I did see her name listed with one of those. |
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Post by nylefty on Mar 21, 2018 16:17:49 GMT -5
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Post by comnkd on Mar 21, 2018 16:55:59 GMT -5
Mannkind should clarify RLS’s involment and correct if it’s wrong. Mike keeps promising information about RLS but we are still waiting. I wonder if RLS will still be listed on the next set of presentation slides. I did see Andrea Bay-Lione’s (sp) name mentioned in the trial info. Mike spoke about RLS during the Oppenheimer presentation. RLS is manufacturing an inhaled version of cannabinoid for chemo patients dealing with nausea and vomiting. RLS’s treatment will compete with the slower acting oral synthetic, Marinol. |
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Post by mnholdem on Mar 21, 2018 17:39:35 GMT -5
Yep. Only a 5 minute onset compared to 1 to 2-1/2 hours for the other brands listed PLUS no effect on appetite, which the others cannot claim. I'm hoping that ,with Andrea helping with its development, an IND will soon be filed. That may trigger a 2nd milestone payment, too.
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Post by peppy on Mar 21, 2018 17:57:54 GMT -5
Yep. Only a 5 minute onset compared to 1 to 2-1/2 hours for the other brands listed PLUS no effect on appetite, which the others cannot claim. I'm hoping that ,with Andrea helping with its development, an IND will soon be filed. That may trigger a 2nd milestone payment, too.  |
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Post by digger on Mar 21, 2018 22:07:17 GMT -5
Yep. Only a 5 minute onset compared to 1 to 2-1/2 hours for the other brands listed PLUS no effect on appetite, which the others cannot claim. I'm hoping that ,with Andrea helping with its development, an IND will soon be filed. That may trigger a 2nd milestone payment, too. When did he said there was no effect on appetite? That hardly seems possible since that's the main reason for using dronabinol to treat AIDS anorexia -- to boost their appetite. |
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Post by mnholdem on Mar 22, 2018 4:42:52 GMT -5
Perhaps I misinterpreted "food effect". I'll have look at that more closely.
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Post by peppy on Mar 22, 2018 6:17:00 GMT -5
Yep. Only a 5 minute onset compared to 1 to 2-1/2 hours for the other brands listed PLUS no effect on appetite, which the others cannot claim. I'm hoping that ,with Andrea helping with its development, an IND will soon be filed. That may trigger a 2nd milestone payment, too. When did he said there was no effect on appetite? That hardly seems possible since that's the main reason for using dronabinol to treat AIDS anorexia -- to boost their appetite. I think the first effect it has on food, is food can be kept down, vs emesis. Perhaps there are no munchies.  |
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Post by digger on Mar 22, 2018 8:39:10 GMT -5
When did he said there was no effect on appetite? That hardly seems possible since that's the main reason for using dronabinol to treat AIDS anorexia -- to boost their appetite. I think the first effect it has on food, is food can be kept down, vs emesis. Perhaps there are no munchies. No, I think it refers to the effect that food has on drug absorption. Being inhaled, obviously food would not affect absorption. |
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Post by peppy on Mar 22, 2018 8:44:00 GMT -5
I think the first effect it has on food, is food can be kept down, vs emesis. Perhaps there are no munchies. No, I think it refers to the effect that food has on drug absorption. Being inhaled, obviously food would not affect absorption. oh, thanks you figured it out. You came in handy once. |
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Post by mnholdem on Mar 22, 2018 8:44:46 GMT -5
That makes sense...consistent delivery of the desired API dosage may be one of the biggest benefits of pulmonary delivery technology.
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