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Post by dreamboatcruise on Mar 27, 2018 10:19:09 GMT -5
I’ve done some searching also, on the clinical trials website. Perhaps they hid it well or perhaps they are doing it in another country, or perhaps a combination of the aforementioned and by another company such as GW Pharma, or something. Or something. If they want to use it for FDA approval they need to register it even if it is carried out in a foreign country. Often large trials involve international sites. It seems you are not at all a believer in Occam's razor, so I shall postulate it involves a secret society of ninjas operating from black sites in South America. This is why Mike only teases us with mention of RLS but few details, lest he be taken out by a ninja star mid presentation. |
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Post by hellodolly on Mar 27, 2018 13:27:14 GMT -5
I’ve done some searching also, on the clinical trials website. Perhaps they hid it well or perhaps they are doing it in another country, or perhaps a combination of the aforementioned and by another company such as GW Pharma, or something. Or something. If they want to use it for FDA approval they need to register it even if it is carried out in a foreign country. Often large trials involve international sites. It seems you are not at all a believer in Occam's razor, so I shall postulate it involves a secret society of ninjas operating from black sites in South America. This is why Mike only teases us with mention of RLS but few details, lest he be taken out by a ninja star mid presentation. The simplest explanation is usually the right one. |
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Post by mango on Apr 27, 2018 17:58:37 GMT -5
The stability of the cannabinoid acids (precursors) is poor. Phytocannabinoids (THC and CBD, etc...) are secondary compounds---they must undergo decarboxylation. Decaroxylation is dependent on two factors: heat and time. The issue is that the precursors are important and have numerous therapeutic properties (differing from their decarboxylated form) but are extremely difficult to work with because of their volatile stability.
Technospehere could, I would think, provide a solution to studying the acids. The properties of FDKP with-in-of-itself could/can be adjusted to accommodate for the degradation factors typical for producing the carboxylated states and could theoretically be prevented utilizing protection with FDKP particles.
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Post by nylefty on May 14, 2018 20:15:43 GMT -5
apnews.com/9d36d2784bf94c7684f03b014989e17f/Marijuana-growers-turning-to-hemp-as-CBD-extract-explodesSPRINGFIELD, Ore. (AP) — A glut of legal marijuana is driving Oregon pot prices to rock-bottom levels, prompting some nervous growers to start pivoting to another type of cannabis to make ends meet — one that doesn’t come with a high. Applications for state licenses to grow hemp — marijuana’s non-intoxicating cousin — have increased more than twentyfold since 2015, making Oregon No. 2 behind Colorado among the 19 states with active hemp cultivation. The rapidly evolving market comes amid skyrocketing demand for a hemp-derived extract called cannabidiol, or CBD, seen by many as a health aid. In its purified distilled form, CBD oil commands thousands of dollars per kilogram, and farmers can make more than $100,000 an acre growing hemp plants to produce it. That distillate can also be converted into a crystallized form or powder. (snip) Like marijuana, the hemp plant is a cannabis plant, but it contains less than 0.3 percent of THC, the compound that gives pot its high. Growing industrial hemp is legal under federal law, and the plant can be sold for use in things like fabric, food, seed and building materials. But the increasing focus in Oregon is the gold-colored CBD oil that has soared in popularity among cannabis connoisseurs and is rapidly going mainstream. At least 50 percent of hemp nationwide is being grown for CBD extraction, and Oregon is riding the crest of that wave, Eric Steenstra said, president of Vote Hemp, a nonpartisan organization that advocates for pro-hemp legislation. (snip)
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Post by digger on May 15, 2018 8:57:22 GMT -5
apnews.com/9d36d2784bf94c7684f03b014989e17f/Marijuana-growers-turning-to-hemp-as-CBD-extract-explodesSPRINGFIELD, Ore. (AP) — A glut of legal marijuana is driving Oregon pot prices to rock-bottom levels, prompting some nervous growers to start pivoting to another type of cannabis to make ends meet — one that doesn’t come with a high. Applications for state licenses to grow hemp — marijuana’s non-intoxicating cousin — have increased more than twentyfold since 2015, making Oregon No. 2 behind Colorado among the 19 states with active hemp cultivation. The rapidly evolving market comes amid skyrocketing demand for a hemp-derived extract called cannabidiol, or CBD, seen by many as a health aid. In its purified distilled form, CBD oil commands thousands of dollars per kilogram, and farmers can make more than $100,000 an acre growing hemp plants to produce it. That distillate can also be converted into a crystallized form or powder. (snip) Like marijuana, the hemp plant is a cannabis plant, but it contains less than 0.3 percent of THC, the compound that gives pot its high. Growing industrial hemp is legal under federal law, and the plant can be sold for use in things like fabric, food, seed and building materials. But the increasing focus in Oregon is the gold-colored CBD oil that has soared in popularity among cannabis connoisseurs and is rapidly going mainstream. At least 50 percent of hemp nationwide is being grown for CBD extraction, and Oregon is riding the crest of that wave, Eric Steenstra said, president of Vote Hemp, a nonpartisan organization that advocates for pro-hemp legislation. (snip) Of course, when they start switching to hemp, that will drive down the cost of the CBD oil, and that $100,000 an acre will rapidly shrink. Welcome to the life of a farmer. |
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Post by mango on May 17, 2018 0:53:53 GMT -5
apnews.com/9d36d2784bf94c7684f03b014989e17f/Marijuana-growers-turning-to-hemp-as-CBD-extract-explodesSPRINGFIELD, Ore. (AP) — A glut of legal marijuana is driving Oregon pot prices to rock-bottom levels, prompting some nervous growers to start pivoting to another type of cannabis to make ends meet — one that doesn’t come with a high. Applications for state licenses to grow hemp — marijuana’s non-intoxicating cousin — have increased more than twentyfold since 2015, making Oregon No. 2 behind Colorado among the 19 states with active hemp cultivation. The rapidly evolving market comes amid skyrocketing demand for a hemp-derived extract called cannabidiol, or CBD, seen by many as a health aid. In its purified distilled form, CBD oil commands thousands of dollars per kilogram, and farmers can make more than $100,000 an acre growing hemp plants to produce it. That distillate can also be converted into a crystallized form or powder. (snip) Like marijuana, the hemp plant is a cannabis plant, but it contains less than 0.3 percent of THC, the compound that gives pot its high. Growing industrial hemp is legal under federal law, and the plant can be sold for use in things like fabric, food, seed and building materials. But the increasing focus in Oregon is the gold-colored CBD oil that has soared in popularity among cannabis connoisseurs and is rapidly going mainstream. At least 50 percent of hemp nationwide is being grown for CBD extraction, and Oregon is riding the crest of that wave, Eric Steenstra said, president of Vote Hemp, a nonpartisan organization that advocates for pro-hemp legislation. (snip) Of course, when they start switching to hemp, that will drive down the cost of the CBD oil, and that $100,000 an acre will rapidly shrink. Welcome to the life of a farmer. A large % of CBD oil sold on the market has always been processed using industrial hemp and then deliberate false claims about the oil are made and people are ripped off. This has been going on for a long time. Industrial hemp contains such a small amount of CBD to start with that an enormous and ungodly amount of material is required to extract a small amount of CBD. Some of these so-called CBD oils contain no CBD at all. |
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Post by dreamboatcruise on May 17, 2018 0:56:46 GMT -5
Of course, when they start switching to hemp, that will drive down the cost of the CBD oil, and that $100,000 an acre will rapidly shrink. Welcome to the life of a farmer. A large % of CBD oil sold on the market has always been processed using industrial hemp and then deliberate false claims about the oil are made and people are ripped off. This has been going on for a long time. Industrial hemp contains such a small amount of CBD to start with that an enormous and ungodly amount of material is required to extract a small amount of CBD. Some of these so-called CBD oils contain no CBD at all. That would make it a homeopathic cure? |
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Post by mango on May 17, 2018 2:02:19 GMT -5
A large % of CBD oil sold on the market has always been processed using industrial hemp and then deliberate false claims about the oil are made and people are ripped off. This has been going on for a long time. Industrial hemp contains such a small amount of CBD to start with that an enormous and ungodly amount of material is required to extract a small amount of CBD. Some of these so-called CBD oils contain no CBD at all. That would make it a homeopathic cure? Funny, I just read on Wiki they are now having to use quantum physics to try to explain things in homeopathy. Somehow the placebo effect is a foundational standard used in clinical trials for Orthodox medicine and yet homeopathy is considered quackery. Obviously someone is confused, and his name was Abraham Flexner. Homeopathy cannot be quackery as long as the placebo effect is used in clinical trials for Orthodox medicine. |
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Post by digger on May 17, 2018 6:58:04 GMT -5
That would make it a homeopathic cure? Funny, I just read on Wiki they are now having to use quantum physics to try to explain things in homeopathy. Somehow the placebo effect is a foundational standard used in clinical trials for Orthodox medicine and yet homeopathy is considered quackery. Obviously someone is confused, and his name was Abraham Flexner. Homeopathy cannot be quackery as long as the placebo effect is used in clinical trials for Orthodox medicine. Quackery implies either ignorance or deliberate fraud. By ignorance, it is meant lack of scientific evidence of the mechanism something works and the ability to replicate treatment under different circumstances -- for example, with different therapists. Technically, acupuncture is quackery. No one knows how to discern "qi" or "meridians." No one knows how to discern whether the "qi" is flowing along the correct "meridian" during treatment. By the same token, what studies have found is that it doesn't matter whether a needle is inserted in any particular meridian -- one works just as well as another. When acupuncture does work, it is likely due to a placebo effect. The placebo effect is well known -- a patient perceives an improvement or in worsening of a condition due to personal expectations. The effect can be tested scientifically and is used in many trials as the basis for determination of true effectiveness of a drug. Homeopathy allegedly administers negligible amounts of a compound that if given in higher doses would produce symptoms similar to the illness the patient presents. There simply is no science to justify such a claim. Moreover, there are no scientifically valid trials showing that one particular homeopathic mixture produces anything more than a placebo effect. |
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Post by mango on May 17, 2018 7:29:58 GMT -5
Funny, I just read on Wiki they are now having to use quantum physics to try to explain things in homeopathy. Somehow the placebo effect is a foundational standard used in clinical trials for Orthodox medicine and yet homeopathy is considered quackery. Obviously someone is confused, and his name was Abraham Flexner. Homeopathy cannot be quackery as long as the placebo effect is used in clinical trials for Orthodox medicine. Quackery implies either ignorance or deliberate fraud. By ignorance, it is meant lack of scientific evidence of the mechanism something works and the ability to replicate treatment under different circumstances -- for example, with different therapists. Technically, acupuncture is quackery. No one knows how to discern "qi" or "meridians." No one knows how to discern whether the "qi" is flowing along the correct "meridian" during treatment. By the same token, what studies have found is that it doesn't matter whether a needle is inserted in any particular meridian -- one works just as well as another. When acupuncture does work, it is likely due to a placebo effect. The placebo effect is well known -- a patient perceives an improvement or in worsening of a condition due to personal expectations. The effect can be tested scientifically and is used in many trials as the basis for determination of true effectiveness of a drug. Homeopathy allegedly administers negligible amounts of a compound that if given in higher doses would produce symptoms similar to the illness the patient presents. There simply is no science to justify such a claim. Moreover, there are no scientifically valid trials showing that one particular homeopathic mixture produces anything more than a placebo effect. Abraham Flexner, the man from Kenucky with a degree in ancient Greek literature, reformed and standardized medical education. Medical Quackery exists because of him penning every medical discipline outside of orthodox medicine as quackery. "The placebo effect is well known -- a patient perceives an improvement or in worsening of a condition due to personal expectations. The effect can be tested scientifically and is used in many trials as the basis for determination of true effectiveness of a drug." If the patient "perceives an improvement" or percieves anything for that matter, it is not manifested physiologically by having personal expectations before, during, and after taking a fake drug. Perception is awareness. I do not need to measure my own awareness against your awareness to validate that my own perception is real. The body is actually reacting. Perception is experienced through the body's senses. In real life, a fake pill is exactly that, a fake pill. The human brain is pretty amazing. This is why in real life no one becomes aware of experiencing a placebo effect. What is experienced outside of a controlled experiement where nothing is infact controlled, includings someone's perception, is quackery. Placebo is measured against the actual drug because placebo is equal to X, in that settings and only to the people that know this already. Placebo demonstrates how awesome the human mind is. Perception is not opinion. Perception is awareness. Perception is felt with the body's senses. Placebo effect is not an opinion, if it were, opinions would matter in clinical trials. Likewise, clinical trials are a known and proven failure. Highly unreliable. Can placebo be used to evaluate and compare real life evidence? How? Randomized, controlled double blind etc etc and on and on clinical trials are most definitely quackery. If the FDA considers one's perception as a scientific principle and a demonstrable fact, then why does the FDA ignore people's opinions? Any guesses? |
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Post by mnholdem on May 17, 2018 7:39:44 GMT -5
This discussion has gone off on a tangent and your hemp/homeopathy/quackery discussion has no direct bearing on Receptor Life Sciences. I suggest that you continue your debate via Private Message so we can keep this thread on topic.
Thank you!
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