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Post by joeypotsandpans on Jan 16, 2018 14:55:41 GMT -5
The kids take theirs 10 minutes into a meal, they eat fast. the latest and greatest I read/saw is 20 mins after the start of the meal. I was surprised. vex saids 15 to 20 mins. it was the tube video of Matt B mattdownunder he said 20 mins into the meal. I would do VDEX. So much proof and work there. Teenagers, they do eat fast, they can be done in 10 mins. dosing: www.seventhform.com/vdexdownloads/vdex-whitepaper-072817.pdf page 22. Comments
Afrezza’s speed of action is both a blessing and a curse. Clearly, it is a large factor in the safety of the
product, but for longer meals, you may need more Afrezza to keep the post prandial levels in check. We
recommend follow-on doses. For example, we advise with a standard meal to dose Afrezza 15-20
minutes after the start of the meal, and then another dose of the same size about 45 minutes later.
With very long meals, we have even advised patients to administer two follow-on doses, for very tight
control.
Read more: mnkd.proboards.com/thread/7878/afrezza-starting-titrating#ixzz54NUHT5aqThis is spot on, this is how I have been dosing and with the Libre it really helps regarding your altitude, I liken the Libre to an altimeter and flying, it lets me know if I need to pull back on the throttle or give it some gas (afrezza) and depending on meal, when and how much. It has only taken me about two weeks with the Libre now to fine tune and hone in keeping my "flight path" closer to in-range. So again, depending on one's metabolism, diet, exercise, etc. it would correlate with timing and frequency of dosing. It varies from day to day depending on the variables. Hope that helps make sense but that is what Vdex is basically saying in the above statement. Here's the bottom line however, having the ability to control spikes with Afrezza and "dial in" has brought my BG avg down over 100 mg/dL (milligrams/deciliter) since I started my readings on 1/3. I so look forward to my next set of labs  , can't wait to see quite a few reactions AND collect on some family bets  |
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Post by joeypotsandpans on Jan 16, 2018 14:04:02 GMT -5
Googling suggests that firm is one of the smallest brokerages in the country and has only four offices in Florida. Is presenting there really worth the cost, time, and effort? So why does their website show offices in New York & Boston then? That's what came up when I went "digging", please source your link to the above referenced by you, thank you Source: noblecapitalmarkets.com/testimonialsContact NOBLE CAPITAL MARKETS BOSTON OFFICE 160 Federal Street, 21st Floor Boston, MA 02110 T +1 617-692-9346 Trading: +1 617-692-4344 F: +1 857-362-7350NEW YORK OFFICE 733 3rd Avenue, 16th Floor New York, NY 10017 T:+1 646-790-5873BOCA RATON OFFICE HQ 225 N.E. Mizner Boulevard Suite 150 Boca Raton, FL 33432 T +1 561-994-1191 Trading: +1 561-998-5489 F: +1 561-994-5741 FINRA | SIPC | MSRB | FINRA’s BROKERCHECK | PRIVACY | BUSINESS DISRUPTION | MARGIN | EXECUTION STATS | EXTENDED HOURS |
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Post by joeypotsandpans on Jan 10, 2018 17:20:34 GMT -5
That Dexcom sensor can send the info to a smartphone and from there, automatically send the data to Verily. Every 5 minutes, patient Doe sends their glucose reading. Smartphone has accelerometer to track activity. Smartphone can be loaded with apps the help coach the patient. Healthcoach and txt patient to set up time to speak and patient can talk to health coach , dietician, CNP with a diabetes specialty about anything that impacts patient Doe's diabetes. Follow up as well. Wanna see a hospital that has no patient beds? www.mercyvirtual.netMy understanding of HIPAA is that the data could not be sent to third party even with identity stripped unless consent is given. There are real concerns about the ability to identify individuals even when their nominal identity (name or social security number) has been stripped. Onduo, which is a spin off of Verily, is one of those companies that provides app and remote coaching. When one consents to use Onduo they are likely consenting to Onduo using the data for analysis and coaching purposes. Though still, that doesn't give Onduo right to share/sell data... likely not even sharing with Sanofi or Verily (its owners). I consider that a relative non issue, what's the difference between that and the standard form the patient signs when they check in for the first time giving consent for the physician to share lab results etc., with any referring physicians, etc...I would venture to say that most patients sign those forms without even reading past the first paragraph. |
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Post by joeypotsandpans on Jan 9, 2018 15:22:04 GMT -5
I originally was going to post this on the thread about the sales and marketing individual who accepted a position at the other company but think it is more appropriate here.
From what I understand there have been a fair amount that have come over from DEXCOM that are now in the sales and marketing area, what I was told is that they (the hires that came from DEXCOM) see MNKD the same as DEXCOM was 5 yrs. ago and know that this is the way the treatment will be heading. They are also very committed and understand the educational aspect of the new paradigm with physicians as well as patients. Now with the availability of the lesser expensive Libre which is much more conducive to real time monitoring for T2's it will help significantly with each T2 individual's situation ie., the differences in metabolism, other medications they are taking, etc.
It isn't like there is a uniform dosing/titration that covers everyone, each T2 requires different regimens depending on where they are on the spectrum of disease progression...for example, Spiro only requires 4u at mealtime and a 4u correction dose when snacking and that is enough to keep him in range...I on the other hand require 8-12u at mealtime with a 4u correction dose depending on carbs at mealtime. I suspect this (lack of understanding by the physicians regarding same) along with the insurance issues were the biggest culprits regarding the drop off in refills. With the ability to constantly monitor this will help tremendously with the learning curve they will continue to go through with the shift towards real time management of the disease.
I can definitely envision a joint marketing endeavor between MNKD and Abbott and/or DEXCOM at some point as it would be akin to the wireless carriers model with the various phones they market in packages IMO.
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Post by joeypotsandpans on Jan 9, 2018 15:16:50 GMT -5
joeypotsandpans ... would be interesting to know of your Afrezza supportive doc, what percent of patients needing to have prandial added to their treatment is he now prescribing Afrezza? Is it basically all that have insurance coverage? Is he switching some patients already on RAA to Afrezza? Good questions, I can ask on next visit |
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Post by joeypotsandpans on Jan 8, 2018 14:26:55 GMT -5
I met with my new endo friday, they took my Libre and downloaded the data and printed out the graphs etc. This particular endo has been working with Afrezza since its inception with Sanofi. You can tell he has experience with it as he is starting me out on a specific regimen with an initial dose with each meal and then if above target range after 2 hrs. a supplemental correction dose. The previous endo I recently went to if you recall I was her first patient she was seeing on Afrezza as they were part of the OPTUM network (UHC) and although she was enthusiastic now that my coverage has changed for the better I went with the one experienced and has worked with the local reps (both prior rep that was with SNY and now with DEXCOM and the current rep that was with DEXCOM and now with MNKD) The reason I bring this up on this particular thread is because at the end of my visit I asked, so overall what are your thoughts about Afrezza? He used the specific term in the title of this thread, his response was very direct....."GAME CHANGER!!" ...he did add the biggest issue was coverage but he had the Afrezza posters both in the waiting rooms and in the room I was attended to so it showed his commitment and advocacy of the product. BTW, his waiting room was at full capacity. He is pretty high on the DEXCOM, I was his first patient that was using the Libre, he has seen many with the freestyle Pro over the last few mos. He asked why I chose the Libre over the DEXCOM since I knew the DEXCOM rep formerly from SNY....I said primarily the cost difference and then joked...well she bailed on Afrezza to which he correctly replied no SNY bailed on her
If you had the time and your old doc had the time it would be interesting to explain the protocol and share your results.Absolutely, as you have witnessed with other testimonials where they posted their graphs from CGM's it reflects the same direct correlation when dosing with Afrezza. If I have a spike from mealtime intake it "attacks" the spike and brings down to range target quickly....regarding the "old doc" they had no real protocol because I had to educate them, the current endo is just the opposite, he has experienced working with Afrezza for awhile now and actually is setting me up on a daily regimen/protocol along with a bi-weekly monitoring of how it is going...I have to email him my downloaded data from the Libre every two weeks...he's on top of his game |
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Post by joeypotsandpans on Jan 8, 2018 14:20:00 GMT -5
and according to the latest from the as he states "non-conflicted" lol SO, his latest article regarding ARNA (of which he is long) he refers to Wells Fargo analyst that gives a $25/sh valuation boost for ARNA's possible treatment for PAH. www.investorvillage.com/groups.asp?mb=19370&mn=12274&pt=msg&mid=17842603the part about favorable FDA environment is akin to what Mike stated on the conference call regarding their conversations with the FDA regarding the technosphere application for Trepostinil. Where's Mike's checklist again? |
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Post by joeypotsandpans on Jan 7, 2018 17:04:36 GMT -5
I met with my new endo friday, they took my Libre and downloaded the data and printed out the graphs etc. This particular endo has been working with Afrezza since its inception with Sanofi. You can tell he has experience with it as he is starting me out on a specific regimen with an initial dose with each meal and then if above target range after 2 hrs. a supplemental correction dose. The previous endo I recently went to if you recall I was her first patient she was seeing on Afrezza as they were part of the OPTUM network (UHC) and although she was enthusiastic now that my coverage has changed for the better I went with the one experienced and has worked with the local reps (both prior rep that was with SNY and now with DEXCOM and the current rep that was with DEXCOM and now with MNKD) The reason I bring this up on this particular thread is because at the end of my visit I asked, so overall what are your thoughts about Afrezza? He used the specific term in the title of this thread, his response was very direct....."GAME CHANGER!!" ...he did add the biggest issue was coverage but he had the Afrezza posters both in the waiting rooms and in the room I was attended to so it showed his commitment and advocacy of the product. BTW, his waiting room was at full capacity. He is pretty high on the DEXCOM, I was his first patient that was using the Libre, he has seen many with the freestyle Pro over the last few mos. He asked why I chose the Libre over the DEXCOM since I knew the DEXCOM rep formerly from SNY....I said primarily the cost difference and then joked...well she bailed on Afrezza to which he correctly replied no SNY bailed on her |
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Post by joeypotsandpans on Jan 3, 2018 20:28:40 GMT -5
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Post by joeypotsandpans on Jan 3, 2018 19:39:56 GMT -5
Yes Peppy, went to CVS to get script RENEWED today, had to get them to correct from the old script of 90 4 unit cartridges to the 60/60/60 count box....copay with Express Scripts only 50 smackaroos and even better was picking up my Freestyle Libre with co-pays as well, comes w/3 10 day sensors...I call this tremendous PROGRESS!!! ....or as you would say Peppy Huge Hair Day Little NYE story for you, was at a pretty large (about 100 tables of 10) dinner party and when taking my Afrezza one of the wives of another guest inquired about it. Turns out her husband who was paying attention to the band is T2 and when she heard it was insulin put her finger over her mouth as to infer shhhh...then she pointed to her husband, I mouthed is he T2? She nodded affirmative....so I inhaled and showed her how incredibly easy it was, I guess she was so taken by it...she tapped her husband on the shoulder and told him to turn around and explained what I had just inhaled. He couldn't believe it so I handed him the dreamboat and the cartridge....he just looked amazed. Turns out they were from Vancouver BC so I told them it wasn't available in Canada yet, however they were pretty close to the Washington border and gave them the Mannkind contact info. I can't wait to take out the Libre now and wave it by my arm to get my BG reading and show that off as well....it will take time but when this senior gets done, a lot of other seniors are going to be educating their physicians and/or endo's. They will also know about Express Scripts as opposed to UHC and affiliates....one brick at a time, eventually the wall crumbles, what a difference a year makes Good stuff Joey. Did you have the same insurance in 2017 and if so what was the co-pay then? How much co-pay for the Freestyle? You mean you've been on this board for almost two years and you're asking me that insurance question? If I was invested in this company and there was a poster pounding the table about the insurance issues from day 1 along with their own personal experience regarding their carrier on many posts I would certainly be paying attention. Please don't take that the wrong way, just was kind of surprised about the question especially with the sticky that has been on the board for the last few weeks regarding United Healthcare....so to answer your question, no to my detriment, I had United Healthcare the last two years which fought tooth and nail to keep me from obtaining Afrezza. I was able to switch to Express Scripts beginning this year which led me to get to the pharmacy asap yesterday. The co-payment for the Libre was $65 for the reader, and $75 for the monthly supply of sensors. So my monthly out of pocket going forward for both Afrezza and the sensors will only be $125/mo (for which I will gladly sacrifice one steak and potato dinner ) to stay in range, live a healthier and hopefully extended life, and as a bonus remain needle and prick free The cherry on top will be really PRICK (you know who they are lol) free when the rest of society both medically and socially have their awakening which I suspect is a lot closer than it was when Sanofi was in charge. I saw numbers today that I haven't seen since I can remember, I am looking forward to collecting on some bets come March when I receive my next set of labs I am so stoked about this combination of Afrezza and the Libre, truly amazing breakthroughs...I would go long Abbott as well because although the CGM may be the current monitor of choice, this one is perfect for T2's and a heck of a lot less expensive and very convenient....can an individual take a 4 hour drive from Vegas to LA and not have to worry about stopping to inject or prick fingers to check your BG levels on an hourly basis....instead you can just take the Libre reader wave it by the sensor outside of your clothes and then take a correction breath if needed....again amazingly powerful and so easy, yes it seems too good to be true but it really is THE REAL DEAL combination and I'm now experiencing what the founding father visionary knew way back when. |
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Post by joeypotsandpans on Jan 3, 2018 1:19:11 GMT -5
what is really interesting about MNKD/AFREZZA is everyone and their brother can see this stuff works great. All they have to do is look at a continuing glucose monitor. All we need is insurance. Joey now has a prescription and is coverage by insurance,
things have changed.Smoke and mirrors insurance. Afrezza works great. "Afrezza insulin human,keeps your blood glucose from going high in the first place." Deerfield can see the stuff works great. Yes Peppy, went to CVS to get script RENEWED today, had to get them to correct from the old script of 90 4 unit cartridges to the 60/60/60 count box....copay with Express Scripts only 50 smackaroos and even better was picking up my Freestyle Libre with co-pays as well, comes w/3 10 day sensors...I call this tremendous PROGRESS!!! ....or as you would say Peppy Huge Hair Day Little NYE story for you, was at a pretty large (about 100 tables of 10) dinner party and when taking my Afrezza one of the wives of another guest inquired about it. Turns out her husband who was paying attention to the band is T2 and when she heard it was insulin put her finger over her mouth as to infer shhhh...then she pointed to her husband, I mouthed is he T2? She nodded affirmative....so I inhaled and showed her how incredibly easy it was, I guess she was so taken by it...she tapped her husband on the shoulder and told him to turn around and explained what I had just inhaled. He couldn't believe it so I handed him the dreamboat and the cartridge....he just looked amazed. Turns out they were from Vancouver BC so I told them it wasn't available in Canada yet, however they were pretty close to the Washington border and gave them the Mannkind contact info. I can't wait to take out the Libre now and wave it by my arm to get my BG reading and show that off as well....it will take time but when this senior gets done, a lot of other seniors are going to be educating their physicians and/or endo's. They will also know about Express Scripts as opposed to UHC and affiliates....one brick at a time, eventually the wall crumbles, what a difference a year makes |
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Post by joeypotsandpans on Dec 22, 2017 15:18:50 GMT -5
Looks like the shorts are leaving us a lump of coal in our stocking for Christmas. Maybe we end the day in the red after such a hopeful beginning to the day. Someday, they will get what they so richly deserve. They may be leaving a lump of coal "on borrowed time" but MNKD gave me (and other PWD) the best gift of all and its the gift that keeps on giving year round The shares that continue on borrowed time will have to come home to roost sooner or later, they didn't come home to roost at near 100% gains so that still is the question that has yet to be answered....sounds like a potential enigma to me.....it's like owing the bookie and the chasing the bet and doubling down hoping to get "square" at some point prior to settlement day lol...sometimes they get lucky but more often it doesn't end up well. Looks like this one could end up as a bad beat considering they were near the full profit area and let it slip away......oh that's right according to SO they could let an almost 100% gain slip away because it was hedged with a convertible note lol...so no reason not to let those profits evaporate instead of realizing it twice so to speak....gifts that keep on giving |
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Post by joeypotsandpans on Dec 22, 2017 13:34:57 GMT -5
joeypotsandpans like I wrote before, Osborne has never deleted my posts but Feroldi does, hence the reason I quit posting on Feroldi's articles. In regards to PAH, I respectfully disagree. I don't see a conflict owing shares in Arena and writing about MannKind. Completely different products and by the way, MannKind much work to do before I would consider it a product. Respectfully disagree with that thought process....the same could be said for Arezza compared to the other Raa's, completely different products but still competing in the same market. Regarding the much work to do, we don't know that unless you have had discussions with MNKD directly regarding same. They alluded to the positive response that they received from the FDA due to the drug already approved in an alternative form, so it is hard to say what the time frame would be, ARNA is still in trials on a drug that has not been approved yet so IMO they may have the bigger hurdle to clear pending trial results etc. Again, he (Osborne) tried to make light of MNKD in regard to being a viable competitor to ARNA, yet they MNKD may have an easier path regarding coming to market with an inhalable form of treprostinil a proven treatment as opposed to one that has not been validated and approved yet. So, I'll just agree to disagree with you on that and take pleasure in knowing that this post won't be deleted Happy Holidays!! |
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Post by joeypotsandpans on Dec 22, 2017 12:08:04 GMT -5
Dear fellow Mannkind Corp. long term stock investors: I've been lurking around here for a very long time, only to subscribe as a member only few days ago after seeing ST falling apart. I wanted you guys to know that I really appreciate the effort, valuable information and quality discussion here and of course writing this to say Merry Christmas and a happy New Year!! It reminds me of me when Yahoo went into the wasteland, now ST, SA is a joke now....same M.O. as the pilot fish swim with the nefarious sharks that are able to pen whatever they want and you're censored if you call them out. Is it any wonder that the membership here keeps growing, I call it natural selection lol.... nat·u·ral se·lec·tion ˈnaCH(ə)rəl səˈlekSHən/Submit nounBIOLOGY the process whereby organisms better adapted to their environment tend to survive and produce more offspring. The theory of its action was first fully expounded by Charles Darwin and is now believed to be the main process that brings about evolutionSame to you, I'll take if a bit further....Happy Holidays to fellow longs and shorts and those on the fence. There will be a day when everyone loves the shorts, they serve purpose at the end of the day, you just have to learn how to live/co-exist with them |
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Post by joeypotsandpans on Dec 22, 2017 11:55:04 GMT -5
Obviously it's a sore spot with him as he has went through the trouble of deleting all my truthful and factual posts. What a hoot this tool is, writes what he wants but can't take the heat in the kitchen when the temperature rises. Knew it when I had my first interaction with him, I inquired why he was writing what amounted at the time to roughly a ratio of about 15/1 articles on one company, he got so defensive in his response it seemed rather odd to me at the time... Kastanes, he is equivalent to the one sided "news" stations (left and right) that run 24/7 a year later after an election that they can't seem to get over. Instead, they alienate the masses with their daily drivel while more important things are happening globally on a daily basis. I call it selective journalism, censorship at its blatant extreme, no worries, it's good to know he reads the proboards or what he terms the echo chamber. When he mentioned that term (echo chamber) I asked him if he had realized what the membership was and the average number of viewers on a daily 24 hr. basis. He then went on with one of his sarcastic rants, I have zero respect for the individual as he has no backbone IMO...keep running from confrontation Spence, it doesn't look good when you write about a company whilst owning another that inherently causes a conflict of interest. The reason Nate and Kovacocy wouldn't come on SA to confront you directly is because you would have their comments deleted in a heartbeat if you couldn't defend and own up to something. Very weak indeed. Your welcome to respond here, your comments won't get deleted here as different points of view are welcomed here in a respectful manner, TG. Kastanes, this is what I get when I attempt to respond, see bold above, he can comment what he chooses yet if I try to respond this is what appears: Thank you for your patience. Your comment is being reviewed by our moderators and will be posted shortly if it is approved. For more info about moderation on Seeking Alpha, click here. Time to posting may be longer outside of US business hours and at times of high comment volume. If your comment is not approved, you may not receive any notification.
I call it selective journalism, censorship at its blatant extreme, So in essence he can say whatever he wants and if someone calls him out on it they are blocked.... Curious Kastanes what would you call it lol? |
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, can't wait to see quite a few reactions AND collect on some family bets 
