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Post by Deleted on Apr 7, 2016 13:41:02 GMT -5
lakon, what if we were on Opra's favorite things list! I can see her holding up the little Dreamboat saying, THIS has changed my life! I could happen, and will with someone at some point. Thanks for the link about Al:-). I still tear up over him being gone, and I seldom cry about anything. Like you say, his plans will be played out. Something tells me when the shorts least expect it:-) So you are saying your investment in MNKD is really that emotionally driven...
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Post by sportsrancho on Apr 7, 2016 13:49:25 GMT -5
lakon, what if we were on Opra's favorite things list! I can see her holding up the little Dreamboat saying, THIS has changed my life! I could happen, and will with someone at some point. Thanks for the link about Al:-). I still tear up over him being gone, and I seldom cry about anything. Like you say, his plans will be played out. Something tells me when the shorts least expect it:-) So you are saying your investment in MNKD is really that emotionally driven... It's my gut. It tells me this stock is way undervalued!
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Post by stevil on Apr 7, 2016 14:04:30 GMT -5
Don't know what other thread I should put this in and didn't want to start one just for this, but I ran into a 1st year pharm student on campus today and they'd said they'd learned about "this new inhaled insulin" in class recently. I'd asked if they'd been taught the PD/PK profile and they didn't seem to know much about it... I thought that was odd, but at least they're being taught about it in school! Even pharmacy school can't get us any added exposure beyond it's inhaled! Really need some studies!!!
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Post by lakon on Apr 7, 2016 14:13:18 GMT -5
Lets not speculate about what MNKD wants to do. The whole altruistic motives for MNKD or Al's actions (about how MNKD wants to _help_ as many patients as possible) is really unprovable. We may wish someone of Mr.Hanks's nature to endorse Afrezza but it won't happen. That costs money. Enough money that MNKD may just survive for an extra couple months to twiddle their thumbs as usual. What's required first and foremost right now is MNKD to articulate a strategy for keeping the lights on through 2016. Celebrity endorsements, TV ads, marketing pushes are all pipe dreams with the cash position right now. I just took the Mann at his word. He seemed trustworthy. A paid endorsement is exactly what I don't want... What's required first and foremost right now is MNKD to execute a strategy. That seems better to me. Talk is cheap. “Whether you think you can, or you think you can't--you're right.” -- Henry Ford Cheers.
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Post by esstan2001 on Apr 7, 2016 14:14:00 GMT -5
Lets not speculate about what MNKD wants to do. The whole altruistic motives for MNKD or Al's actions (about how MNKD wants to _help_ as many patients as possible) is really unprovable. We may wish someone of Mr.Hanks's nature to endorse Afrezza but it won't happen. That costs money. Enough money that MNKD may just survive for an extra couple months to twiddle their thumbs as usual. What's required first and foremost right now is MNKD to articulate a strategy for keeping the lights on through 2016. Celebrity endorsements, TV ads, marketing pushes are all pipe dreams with the cash position right now. The idea in Hank's case would simply be to help him. Increase his awareness, maybe then he decides to try it- provide more assistance with learning proper dosing, then see what happens. If he feels this solves many of his health complications and finds this far and above better than anything else, and he is made aware that this is new, and it is just insulin, who is to say that he does NOT decide to evangelize about it in terms of helping diabetics in our society.. .especially if he learns anything about what Al Mann was trying to do from his Hollywood friends... You certainly can not know for a fact (as you state above) that someone of Hank's 'nature' won't endorse Afrezza. No one knows what he might do if presented with the story and if he experiences outcomes like Spiro, Afrezzauser, Eric, etc. But it sure makes sense to try (minimal effort and cost, and IMO Mnkd should not be looking for a paid celebrity endorsement if that is what you were thinking) among the other plans that the company needs to put forth.
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Post by dictatorsaurus on Apr 7, 2016 14:21:26 GMT -5
Celebrities cannot save this drug or company. I well thought out and executed plan can. So far we don't have any indications one exists or is in works.
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Post by LosingMyBullishness on Apr 7, 2016 14:48:45 GMT -5
A familiar topic:I did some search on this very board about Tom Hanks promoting Afrezza:
mannmade and bradleysbest wrote about it in Aug 14 (mannmade said that he also spoke with Matt about celebrity endorsement back then),
bospec made a list incl. Tom Hanks back in Feb 15, jlaw277 also mentioned him in Feb 15, mannmade picked it up again.
compound26 asked Can we have Tom Hanks starring the ad? in Jul 2015 and factspls88, esstan2001 joined in.
In Aug 15 mannmade dropped Tom Hanks ;-) saying 'I am avoiding the obvious of Tom Hanks, Halle Berry etc.'
...but in Sep 15 it was Tom Hanks again by fldave007 saying 'Why can't someone in management contact Tom Hanks, Halle Berry or...'. Mannmade commented that this is too expensive: 'Have to agree here and as I have posted several times before, it will likely cost Sanofi $500,000 or so just to produce a Network worthy commerical and if they use Tom Hanks or Halle Berry et al, it may cost another 1.5m or more. Then there is the media expense,..'
In Nov 15 rangersfan came up with the splendid idea: 'Tom Hanks announced 2 years ago on the late show with David Letterman that he was a diabetic. If they get him on Afrezza he would go on these shows and tell everyone how great Afrezza is. Millions of people see it including doctors and the beauty is it is FREE advertising. I sent this to Matt but he never responded. What do you think?'
factspls88 came back in Dec 15 with 'Then of course there is the Tom Hanks and Halle Berry option. Could you imagine if they agreed to appear in some Afrezza commercials?'
In Jan 16 I myself made this creative (..) comment: 'Second you need a celebrity that is a diabetic and works for broad audience. Most people see this with guy like Tom Hanks.'
And 5 hours ago myocat posted 'Tell Tom Hanks to start sniffing MNKD powder. I mean inhaling.' going for another wave of Tom Hanks or Hank's.
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Post by kc on Apr 7, 2016 14:54:42 GMT -5
In Touch has exclusively learned that Tom Hanks has been struggling with other serious health conditions in the years since he was diagnosed with type 2 diabetes.
“Tom isn’t just battling diabetes — he’s suffering from prostate flare-ups and other blood sugar problems,” a source close to the two-time Oscar winner reveals. The source states that Tom must take pills multiple times a day to help manage his issues, adding, “The side effects are what’s really affecting him.”
( <----- is backing a way from that train. )
Tom Hanks and other millions of people should have had Pre-diabetes treatment.
The problem is we have to reach the Pre-Diabetic for treatment. Al Mann knew this and never got Afrezza to that stage. You have to treat early with Afrezza before they get to the serious complications that Diabetes brings on. This article on the link from diabetes daily states the case for earlier treatment as we are all walking time bombs for T2D. Afrezza helps the pancreases and gives it a break in dealing with BG. Might Afrezza be the HOLY GRAIL in (Pre) diabetes treatment if used very early? I guess we need more studies to show that being the situation. Maybe that is what MannKind will present at the ADA. Seems to me that Al was pushing in that direction. But you need further clinical data and perhaps we have that now in the papers that will be released.
Read this link on Pre-diabetes being your wake-up call. www.diabetesdaily.com/blog/prediabetes-can-be-your-wake-up-call-266524/
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Post by victoria on Apr 7, 2016 15:43:10 GMT -5
Don't know what other thread I should put this in and didn't want to start one just for this, but I ran into a 1st year pharm student on campus today and they'd said they'd learned about "this new inhaled insulin" in class recently. I'd asked if they'd been taught the PD/PK profile and they didn't seem to know much about it... I thought that was odd, but at least they're being taught about it in school! Even pharmacy school can't get us any added exposure beyond it's inhaled! Really need some studies!!! Hi. Interesting experience, would you be able to post more detail on the conversation? Would be good to know what message students get and how. Thanks
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Post by stevil on Apr 7, 2016 15:55:59 GMT -5
Don't know what other thread I should put this in and didn't want to start one just for this, but I ran into a 1st year pharm student on campus today and they'd said they'd learned about "this new inhaled insulin" in class recently. I'd asked if they'd been taught the PD/PK profile and they didn't seem to know much about it... I thought that was odd, but at least they're being taught about it in school! Even pharmacy school can't get us any added exposure beyond it's inhaled! Really need some studies!!! Hi. Interesting experience, would you be able to post more detail on the conversation? Would be good to know what message students get and how. Thanks She had a test tomorrow and was panicking about having to know the top 175 drugs for her test tomorrow. I didn't really get to talk much about Afrezza... she was just sharing some of her stories and venting a little bit. I threw in a question about prandial insulin to see what she was getting taught and she told me that "there's this new inhaled insulin that just came on the market last year". That's when I'd asked if she'd seen the PK/PD graph, and she said that she couldn't remember, that they didn't spend a lot of time on it, just that they'd mentioned it when they were doing the rapid acting insulins. I took a quick minute to tell her that the profile nearly identically matched the pancreas, but she was like, "cool story, bro". It wasn't really all that informative of an encounter. She was stressed out and it was just a quick conversation in passing. My girlfriend is sitting for her dietitian certification exam this summer when she graduates and I've already started to work on her She can't prescribe, but she'll work closely with patients and physicians in many diabetes cases. I'm doing my part!
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Post by liane on Apr 7, 2016 16:19:40 GMT -5
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Post by stevil on Apr 7, 2016 16:26:53 GMT -5
I'm curious to hear why it isn't done for every drug... Even though I'm usually not swayed by peer pressure, I'd much rather hear about medicine from one of my favorite athletes than all of those boring commercials that play with the awful music. Although my age group probably isn't the target audience for most drugs....
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Post by slugworth008 on Apr 7, 2016 16:31:55 GMT -5
Change the label, and you have a shot. If Dr's wont prescribe you think an A list celebrity is going to Endorse? One A list celeb that has Afrezza positively impact their life - and it's game on and game over. Yeah, they'll endorse it. And a label change won't be required for them to do so.
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Post by peppy on Apr 7, 2016 16:54:39 GMT -5
The problem is, "The source states that Tom must take pills multiple times a day to help manage his issues, adding, “The side effects are what’s really affecting him.” Tom isn’t just battling diabetes — he’s suffering from prostate flare-ups and other blood sugar problems,”
Tom Hanks has money for very good kitchen help that should be able to give favor to real food. If Tom Hanks isn't feeling well it could be the medications he is on. The set up is, "we go to the physicians, he/she gives us pills, we thank them, go home and feel bad." You couldn't write a better story.
Tom's physician must be following the guidelines.
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Post by kball on Apr 7, 2016 18:36:33 GMT -5
Found this a very informative and interesting article. Thanks Liane. Among other things i wasn't aware Mary Lou Retton had a hip replacement about 10 years ago and that she went on to promote that company. Who didn't love our 84 gymnastics teams men and women!
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