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Post by mannmade on Oct 3, 2018 19:06:15 GMT -5
It would also help them justify pricing...
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Post by mannmade on Oct 2, 2018 20:06:25 GMT -5
www.yahoo.com/news/eli-lillys-diabetes-treatment-meets-main-goal-two-103258999--finance.htmlEli Lilly's diabetes treatment meets main goal in two late-stage studies Reuters Reuters 14 hours ago (Reuters) - Eli Lilly and Co said on Tuesday its experimental diabetes treatment was shown to be as effective as the drugmaker's Humalog medicine in two late-stage studies. The study also found that the drug, Ultra Rapid Lispro, significantly improved post-meal blood sugar levels in people with both type 1 and type 2 diabetes and had a similar safety profile as Humalog. Ultra Rapid Lispro is a mealtime insulin formulation being developed to help better control blood glucose levels after meals by more closely mirroring the way insulin works in people without diabetes. Lilly has an large diabetes franchise including Trulicity, Humalog and Humulin. Its bestselling Humalog brought in revenue of $769.8 million in the last quarter. About 30 million Americans suffer from diabetes, of which an estimated 90 to 95 percent have type 2 diabetes.
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Post by mannmade on Sept 28, 2018 16:04:14 GMT -5
Don’t get me wrong as I believe in both hope and faith... however one chooses to define them. However I am just trying to say that each by itself without any action is not a strategy to move the ball forward. We have hope and faith in Mike C but he has a plan that goes beyond just hope and faith...
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Post by mannmade on Sept 28, 2018 15:20:29 GMT -5
Hope is fine... but it does not work to move things forward... I am all for hope as without it there is no positive. However if I go to Las Vegas and Hope I am Going to win.... I am more likely going to lose... now if I instead took lessons on how to play poker or blackjack to learn strategy I increase my chances of winning... GLTAL’s!!!
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Post by mannmade on Sept 28, 2018 13:46:42 GMT -5
Hope is not a strategy... keep the faith!
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Post by mannmade on Sept 26, 2018 16:24:40 GMT -5
Seriously... how can her endo be so ignorant (no disrespect) but a 5.7 that is non diabetic and we see this quite often. How can AFREZZA not be the number one Prandial?  ?? Yes I know the issues... just frustrating when you read stories like the above. |
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Post by mannmade on Sept 26, 2018 16:17:39 GMT -5
Found this on ST as published in Beyond Type 1:
IT’S NO LONGER JUST A NEEDLE GAME
WRITTEN BY: Ginger Gault FacebookTwitterEmail
Talk about a roller coaster ride.
Like most T1Ds, I started with multiple daily injections of long-acting and short-acting insulin. Several years later I started on an insulin pump, which definitely changed my life for the better.
After many years of insulin injections, pump site insertions, and CGM site insertions, however, I started having trouble with insulin absorption because of scar tissue. After years of taking care of myself I was suddenly having the worst blood sugars of my life. When your body doesn’t properly absorb your insulin, it’s impossible to keep your blood sugars stable. You go from highs to lows constantly. My CGM set alarms off all night long, and I had to feed lows throughout the day, leading to rebound highs and weight gain. Talk about frustrating!
I’d heard about Afrezza, the inhaled insulin, a couple years earlier and was interested in trying it. But my endocrinologist said it wasn’t a good fit for a T1D and claimed I could never get the same kind of control as with a pump. At that point I listened to my doctor and gave up. Big mistake! While not all doctors are on board with Afrezza yet, I believe it’s just because they haven’t given it a chance. After having so many problems with insulin absorption, I knew it was time to find an endocrinologist who would prescribe an inhaled version for me. I did just that, and the move has changed my life.
Guess what? My blood sugars stay steady all night long. I’d forgotten what it was like to sleep through the night. Overall my BGLs have shown an average of about 30 points of improvement using inhaled insulin versus a pump. My most recent A1C was 5.7 – the lowest it’s ever been in my 27 years as a T1D.
Not having an insulin pump attached me to 24 hours a day has changed my life as well. I never realized just how much wearing a pump bothered me until it was no longer there. It’s been difficult to get my insurance company to cover for inhaled insulin, but I will keep fighting. Being able to manage my blood sugar is worth i
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Post by mannmade on Sept 7, 2018 15:55:35 GMT -5
Only a guess on my part but am sure they have contingencies for that event which they must judge as remote. Also UTHR seems to have an underlying interest in TS judging by the quick follow up to start and pay for research on other molecules. With that in mind I don’t see them walking away very easily. Just my opinion.
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Post by mannmade on Sept 5, 2018 18:09:52 GMT -5
I once mentioned to Matt P mnkd should try seeing if 5hr Energy would work. Not only would it be faster there would not be the awful taste.
I also mentioned aspirin in a cricket for key chains as a faster way to prevent heart damage when having a heart attack. Am not a doctor but both seems practical and commercially marketable on a mass scale at decent price points.
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Post by mannmade on Sept 5, 2018 18:05:17 GMT -5
True, but I would rather have us put more effort in getting epinephrine out sooner. not sure Epi is best. Liane as a doctor would know more, however as much as I hate needles I am not sure how well inhaling would work when your throat is closing up on you. Just my opinion. |
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Post by mannmade on Sept 5, 2018 12:29:19 GMT -5
Does not need to be a buyout. As Peppy says and I have been telling Sports for the last few years.... best thing that could happen to Mannkind is a deal like Regeneron did with Sanofi. Last time I checked Regeneron stock was $405. And I believe they may have started their relationship with Sanofi similar to way mnkd has with United. We now have a big brother/sister to protect us from big pharma. And they seem to have a different kind of CEO who just may have the right combination of vision, drive, pathos and compassion that we need from a big brother... or sister... GLTAL’s!
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Post by mannmade on Sept 2, 2018 21:22:07 GMT -5
Then I was mistaken but do recall it being mentioned somewhere. So much the better then for what I was trying to say about BK not being an issue imho for the foreseeable future.
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SA
Sept 2, 2018 17:32:47 GMT -5
Post by mannmade on Sept 2, 2018 17:32:47 GMT -5
I did not recal it either until saw it postd on board somewhere before. That's why I put the question mark after it.
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SA
Sept 2, 2018 11:54:09 GMT -5
via mobile
Post by mannmade on Sept 2, 2018 11:54:09 GMT -5
This is not my area of expertise... however as I see it, mnkd really only has 22m to Deerfield, another 15m to Union Bank? And the amphistar contract of about 14m a year. That’s really only $51m
I am obviously not counting the 90m mann foundation Debt as it is very likely going to stay friendly for a while longer.
So mnkd is not in the same financial situation.
Mike has to be able to show anyone who would get involved in financing the tecap that mnkd can get to break even and beyond in next 12 to 18 months that is the key in my opinion. If he can’t then I would start to be concernered about possible BK
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Post by mannmade on Aug 30, 2018 16:21:21 GMT -5
Yes
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??