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Post by mannmade on Feb 20, 2019 10:34:14 GMT -5
I am not so sure about that. As I recall someone mentioned that mnkd assets also tied to milestone payments. However I Have not confirmed.
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Post by mannmade on Feb 8, 2019 17:00:07 GMT -5
Regardless where is the social media campaign geared to them!
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Post by mannmade on Feb 8, 2019 15:50:35 GMT -5
Weren’t we as s/h’s promised more transparency?
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Post by mannmade on Feb 8, 2019 15:42:56 GMT -5
If so they are not doing much... imho
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Post by mannmade on Feb 8, 2019 12:24:53 GMT -5
Yes what is mnkd doing to target it’s message to mellenials and pwd in their late teens, early 20’s to 30’s. They are the tech savvy new adopters! Not sure they are watching CNN, Fox et al... this is where they should run ads on college campus networks, and fb, social media etc...
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Post by mannmade on Feb 8, 2019 11:21:19 GMT -5
Still do not understand why mnkd did not do more with this. It is an endorsement from one of two leading diabetes groups in US. Should also be using with doctors and insurance companies if not already.
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Post by mannmade on Feb 8, 2019 9:17:54 GMT -5
Don’t mess with the Beezer or the Bezos!
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Post by mannmade on Feb 5, 2019 8:52:16 GMT -5
It’s a crowded boat...
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Post by mannmade on Feb 2, 2019 23:33:48 GMT -5
I often disagree with Aged’s posts but I respect that he generally backs them with facts and/or well reasoned rationales. Perhaps he is just too aged to change... not enough to call him a short imho...
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Post by mannmade on Feb 1, 2019 15:32:50 GMT -5
Good catch Joey... one and the same?
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Post by mannmade on Feb 1, 2019 11:07:39 GMT -5
And less expensive... However can’t wait to see included with my Apple Watch.
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Post by mannmade on Feb 1, 2019 11:06:22 GMT -5
Maybe it’ll Work for Type 1: Clinical Trial Results Announced
Published February 1, 2019 in Glucose control, Research News
A protein, called glucokinase (or GK), acts as a key regulator of sugar levels in the body, and its expression is limited to tissues that require sugar-sensing, mainly the liver and pancreatic beta cells. If blood glucose levels are deemed too high, activation of GK in the liver increases glucose utilization which in turn lowers blood glucose.
vTv Therapeutics, has developed a GK activator (GKA) that mainly works in the liver, called TTP399. In a clinical trial in people with type 2 diabetes (T2D), published this month by Science Translational Medicine, they wanted to test if administration of TTP399 was associated with a significant and sustained reduction of HbA1c from baseline to six months of treatment. The results showed that it worked, as the levels of HbA1c in the largest dose of TTP399 were significantly reduced by 0.9 percent. What’s more, in this type 2 population, TTP399 did not cause hypoglycemia, as had been the case with previous GKA that were less liver-specific, and could act in beta cells to increase insulin release. The liver selectivity of this drug, therefore, provides additional rationale for testing the therapeutic potential of TTP399 in type 1 diabetes (T1D).
Although this trial was not funded by JDRF, JDRF has an active interest in GK activators for T1D. vTv Therapeutics and JDRF joined forces in 2017, to test TTP399 in people with T1D. After careful evaluation and establishing collaborations with expert T1D clinicians, vTv is currently carrying out a phase I/II clinical trial. This trial will recruit up to 126 participants, who will receive TTP399 or a placebo as an add-on to insulin. The goal of the trial is to test safety and efficacy in reducing HbA1c after 12 weeks of treatment. For more information on this trial, or to find out if you qualify, go to the ClinicalTrials.gov page here.
If it’s anything like the clinical trial in T2D, it will be a big thing for the T1D community!
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Post by mannmade on Jan 31, 2019 15:52:52 GMT -5
I know it seems like business as usual with mnkd given the low weekly scripts, but imho things do seem to be changing... The doctor Edelman video followed by the Dr. Pettus video. The JDRF statement a few weeks back. Today three different posted articles on how great afrezza is. And a new group of users and pwd posting about being on afrezza or trying to get it. Etc...
Sure the two biggest obstacles remain, doctor education and acceptance and insurance coverage...
But it does seem the times are a changing...
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Post by mannmade on Jan 31, 2019 10:33:13 GMT -5
Agree Boca, I think this is the most fair approach under the recent and current “snapshot” of the companies current position.
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Post by mannmade on Jan 31, 2019 10:31:32 GMT -5
I like seeing the commercial or hearing about it being aired, or hearing about how a diabetic has seen the commercial and been interested enough to investigate further. The fact that this latest campaign appears to be even more broadscale and perhaps on par with other insulin commercials such as Toujeo in terms of air play, air timing (e.g., prime time) and distribution across the varioius media outlets does comfort me in terms of making me feel like I'm invested in a "legitmate" product that I can now perhaps mention in conversation and have people say, "oh yeah, I've heard of Afrezza, that's that inhalable insulin, right?". I like that very much. OK, I have another advertising idea but this time it's not a story board idea for producing a commercial. My wife likes to watch The Price Is Right. I've found over time a suprisingly large number of (I presume mostly older) people like this show. Drew Carey is a good host and George Gray is a good announcer and they and the spokesmodels on the set appear to have a genuine good chemistry. They seem to enjoy interacting with contestants and make the show "fun". i.e., it isn't all about the prizes as much as having fun and getting real joy from giving away good prizes too. I noticed recently that the promotional aspect of products on the show has evolved over time. In the old days they might show a box of Kraft Macaroni & Cheese for instance and George (or his predecessor) would describe the product and mention the manufacturer's name. They don't that nowadays. Instead they mention what the product is, but in a generic way and not it's product or brand name. There are exceptions. When a car is the prize, those get product and manufacturer name. I saw another exception this last week that caught my attention. It was in a line up of common products you might get at a grocery store for the game that was being played for a prize. One of the products was Coricidin HBP which is an over-the-counter antihistamine drug. But the product placement description included the drug name and I think also the manufacturer's name. I don't know how much it would cost or how the FDA would feel about an Afrezza product placement on The Price Is Right, but I assume the producers of the show or at least the makers of Coricidin had to get FDA approval the same as for conventional TV DTC advertising. Given the presumed demographics of the show and the possible lower cost of airtime for a game show, this might be an opportunity to get even more mind share from adult onset T2s (and I think especially those in their "honeymoon" phase). Will never happen for way too many reasons to post. I used to be a compliance attorney for NBC Network when I first started my career and worked on Price and did many integrations of products in programs including a pharma launch in Biggest Loser but that was a very tough sell and really the exception. |
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