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Post by spiro on Nov 17, 2013 15:52:04 GMT -5
ashiwi,
Thanks for posting this information. I had heard before that some Sanofi insulin drug reps have talked about Afrezza. Sanofi would make a great partner. But, I will take any global partner. It is still my opinion that MNKD will announce some type of arrangement before Jan 1. If that happens, things could get quite explosive with MNKD. Since the best argument against Afrezza future success remains Exhubera's failure, I don't think longs have much to worry about.
Spiro
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Post by spiro on Nov 15, 2013 13:06:11 GMT -5
Thanks for this information. So, is it likely that MNKD is using a 2nd party to produce this other insulin, under it's rights acquired from Pfizer? Also, is the Pfizer formulated insulin the only type that can be used with technosphere after approval?
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Post by spiro on Nov 14, 2013 20:31:55 GMT -5
Savzak,
It's nice to see that you have decided to join this message board. I am pretty sure that your opinions and comments will be respected and appreciated here. I also think that you don't have to worry about your personal registration information being outed by the Administrator. I think that there are a lot of good people posting here on this board. I am probably the craziest guy they let post here. Heck, just look at my picture. i am looking forward to reading your future posts.
Spiro
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Post by spiro on Nov 11, 2013 14:07:12 GMT -5
Liame,
Thanks for posting the George Rho response. It's interesting that virtually every negative article has to rely on the Exhubera comparison. The apparent weakness in these hit pieces is actually making me more confident in MNKD's ability to get Afrezza on the market. I think doctor's will be more concerned with helping their patients control their disease, rather than worrying about Exubera's failure. Let me add,and saving their patients lives by reducing severe hypoglycemic events.
Spiro
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Post by spiro on Nov 6, 2013 19:03:34 GMT -5
alethea,
I am not sure I buy tne manipulation theory. There is a lot of trading going on with MNKD every day. Both longs and shorts could be making money trading MNKD. I am sure both longs and some shorts have been hit with margin calls and stop losses the last 2 days. Weak hands will also give up and move on. I am not a trader, I am continuing to accumulate with most every big dip in MNKd's share price. I have probably spent several hundred hours reading every article out there about Afrezza. I have been convinced by my research, that Afrezza / Technosphere will become a mega drug in sales. It amazes me that the failure of Exubera continues to be one of the strongest arguments against Afrezza's potential success. I wonder if Pfizer had a survey showing that 86% of physicians surveyed would prescribe the scuba tank sized Exubera inhaler? I only invest what I can afford to lose. I also try to stay focused on the end game. If I am wrong, I will just call myself stupid, and move on. OK, maybe I will cry myself to sleep for a couple of month's.
Good luck to all longs,
Spiro
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Post by spiro on Nov 5, 2013 16:19:01 GMT -5
Wow, from $4.20 to $5.10, with a close at high for the day. I actually caught the falling knife by tyne handle today and picked up 30 contracts of the Jan 2015, $5 calls for $1,70. So does the runup continue tomorrow?
Spiro
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Post by spiro on Nov 5, 2013 14:21:16 GMT -5
thsloppy,
Nice post, but no golf, LOL. OK, saving your patients lives should be could enough.
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Post by spiro on Nov 2, 2013 13:12:14 GMT -5
Babaoriley,
Build it and they will come, doesn't seem to working so far. it looks like the BP's want the game to start first. It will probably cost them a lot more for the ticket, after the game starts. I try not to think about the corrupt FDA and their politics. It's sad that the FDA is letting people die from severe hypoglycemic events, when they know Afrezza could have already saved numerous lives. Hopefully, Greenhill will get this thing done soon.
Spiro
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Post by spiro on Nov 2, 2013 8:56:21 GMT -5
Reading Articles like these, keeps me focused on the long term prospects for MNKD and Afrezza. China "Perhaps even more alarming, the study, which involved testing almost 99,000 people, found that half had “prediabetic” blood glucose levels." www.nytimes.com/2013/09/10/health/diabetes-epidemic-grows-in-china.html?_r=0
U.S. 33% Pre-Dibetics in U.S. age 20 or older. Wow "Low Awareness of Pre-Diabetes Approximately 1 in 3 U.S. adults age 20 and older have pre-diabetes. Yet 89 percent are unaware of it, according to Doctor YanFeng Li, Division of Diabetes Translation, Centers for Disease Control and Prevention. Dr. Li and her colleagues concluded in their study that the critical first step to encourage people with pre-diabetes to make healthy lifestyle changes to prevent Type 2 diabetes is improving awareness of pre-diabetes. I disagree. I believe the first critical step is a name change and a change in our national conversation. If you are a health care provider, tell your next patient with pre-diabetes that he has Stage 1 diabetes. See what happens. I'm thinking he'll look up and listen hard. Let him know he's at the fork in the road. "Good day, Mr. Gottlieb, I have some bad news and some good news. The bad news is you have Stage 1 Type 2 diabetes. If you do nothing now you are working your way toward Stage 2. However, the good news is together we can work at reversing it, so you may never go on to Stage 2. In the worst case scenario we may be able to delay it for years." www.huffingtonpost.com/riva-greenberg/prediabetes_b_3023146.htmlSpiro
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Post by spiro on Nov 1, 2013 15:00:22 GMT -5
Good grief, an estimated 336 million people in the world have diabetes today, with that number expected to grow to over 552 million by 2030. Almost every major pharmaceutical company has it's eye on this market now. Do you think MNKD is in the right place, at the right time with it's potential game changing Afrezza. "YES" Longs will need some patience, but when our celebration occurs, it will be a big one. www.idf.org/diabetesatlas/5e/the-global-burden
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Post by spiro on Oct 31, 2013 15:47:32 GMT -5
Liane,
Your projections look good to me. The potential value of Afrezza in replacing oral meds and/or early intervention could be huge. Also, after reading that Metformin could be linked to Alzheimer's disease, I am surprised that doctors still prescribe it. Afrezza has a great future and by reducing severe hypoglycemic events, it will save lives. The manipulation taking place with MNKD's share price, hopefully will end soon.
Spiro
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Post by spiro on Oct 25, 2013 10:57:01 GMT -5
mdcenter61,
OK, I told the boys it was off, but they were a little disappointed. They had already formed a chopper gang.
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Post by spiro on Oct 25, 2013 9:41:14 GMT -5
mdcenter61,
So whatta are you trying to finger me. You wanna know too much. Maybe I should send some of the boys over there and have a little talk with you.
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Post by spiro on Oct 21, 2013 9:25:12 GMT -5
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Post by spiro on Oct 21, 2013 9:13:12 GMT -5
I thought doldrums were limited to the summer. OK, so just to keep us focused on why the FDA will approve the much needed Afrezza for both type 1 and type 2's, here is some data from 2011 ADA sheet. Also, check out the state of Michigan fact sheet below this info. Diabetes Fact Sheet Almost 26 million Americans have diabetes, including as many as seven million individuals who have diabetes and don’t know it. Diabetes kills more people than AIDS and breast cancer combined. In 2007, diabetes claimed more than 284,000 American lives. Diabetes costs the American people $218 billion each year, factoring together the total costs of diagnosed cases, undiagnosed diabetes, prediabetes, and gestational diabetes. Diabetes impacts all social, economic, and ethnic backgrounds. The World Health Organization (WHO) estimates that more than 180 million people world wide have diabetes. This number is likely to more than double by 2030. Diabetes is caused by the body’s inability to create or effectively use its own insulin, which is produced by islet cells found in the pancreas. Insulin helps regulate blood sugar (glucose) levels – providing energy to body cells and tissues. Without insulin, the body’s cells would be starved, causing dehydration and destruction of body tissue. Injecting insulin is not a cure for diabetes. It is a critical life-saving component of a daily treatment program. Diabetes is the seventh leading cause of death by disease among adults and reduces life expectancy by one-third. Approximately 4,110 new cases of diabetes are diagnosed each day. Almost three million Americans are hospitalized each year due to diabetes. Diabetes is the leading cause of new blindness in adults ages 20-74. Sixty-five percent of deaths among people with diabetes are due to heart disease and stroke. Persons with diabetes are two to four times more likely to develop heart disease than people without diabetes. More than 60 percent of all nontraumatic amputations occur among people with diabetes. Nearly 44 percent of all kidney failure is caused by diabetes. Diabetic patients are 17 times more prone to kidney disease than people who do not have the disease. Diabetes is also the leading cause of end stage renal disease. Women with diabetes face high-risk pregnancies, which can result in babies born with many health problems. Source: Centers for Disease Control; National Institutes of Health; American Diabetes Association From Michigan: www.michigan.gov/documents/mdch/Diabetes_in_Michigan_Update_2013_416620_7.pdfwww.michigan.gov/documents/mdch/Diabetes_in_Michigan_Update_2013_416620_7.pdf
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